2022 Publications

January 2022

Jan 31

In-Hospital Cardiac Arrest Survival in the United States During and After the Initial Novel Coronavirus Disease 2019 Pandemic Surge. Chan PS, Spertus JA, Kennedy K, Nallamothu BK, Starks MA, Girotra S; American Heart Association’s Get With the Guidelines–Resuscitation Investigators. Circ Cardiovasc Qual Outcomes. 2022 Jan 31:CIRCOUTCOMES121008420. doi: 10.1161/CIRCOUTCOMES.121.008420. PMID: 35098727

Jan 28

Four-day food record macronutrient intake, with and without biomarker calibration, and chronic disease risk in postmenopausal women. Prentice RL, Pettinger M, Neuhouser ML, Raftery D, Zheng C, Gowda GAN, Huang Y, Tinker LF, Howard BV, Manson JAE, Wallace R, Mossavar-Rahmani Y, Johnson KC, Lampe JW. Am J Epidemiol. 2022 Jan 28:kwac017. doi: 10.1093/aje/kwac017. PMID: 35094071

Jan 27

Clinical Phenotypes of Cystic Fibrosis Carriers. Polgreen PM, Comellas AP. Annu Rev Med. 2022 Jan 27;73:563-574. doi: 10.1146/annurev-med-042120-020148. PMID: 35084992. Review.
COVID-19: Inflammatory Profile. Wang Y, Perlman S. Annu Rev Med. 2022 Jan 27;73:65-80. doi: 10.1146/annurev-med-042220-012417. Epub 2021 Aug 26. PMID: 34437814. Review.
Pulmonary Aspects of COVID-19. Doerschug KC, Schmidt GA. Annu Rev Med. 2022 Jan 27;73:81-93. doi: 10.1146/annurev-med-042220-014817. PMID: 35084996. Review.

Jan 26

Postoperative bleeding complications in patients with hemophilia undergoing major orthopedic surgery: A prospective multicenter observational study. Kleiboer B, Layer MA, Cafuir LA, Cuker A, Escobar M, Eyster ME, Kraut E, Leavitt AD, Lentz SR, Quon D, Ragni MV, Thornhill D, Wang M, Key NS, Buckner TW. J Thromb Haemost. 2022 Jan 26. doi: 10.1111/jth.15654. PMID: 35080347
Research Opportunities in Autonomic Neural Mechanisms of Cardiopulmonary Regulation: A Report From the National Heart, Lung, and Blood Institute and the National Institutes of Health Office of the Director Workshop. Mehra R, Tjurmina OA, Ajijola OA, Arora R, Bolser DC, Chapleau MW, Chen PS, Clancy CE, Delisle BP, Gold MR, Goldberger JJ, Goldstein DS, Habecker BA, Handoko ML, Harvey R, Hummel JP, Hund T, Meyer C, Redline S, Ripplinger CM, Simon MA, Somers VK, Stavrakis S, Taylor-Clark T, Undem BJ, Verrier RL, Zucker IH, Sopko G, Shivkumar K. JACC Basic Transl Sci. 2022 Jan 26;7(3):265-293. doi: 10.1016/j.jacbts.2021.11.003. PMID: 35411324. Review.
The Enticing Path of miR Therapeutics: Difficult but Not without Prospects. Vikram A. Cells. 2022 Jan 26;11(3):418. doi: 10.3390/cells11030418. PMID: 35159228
Transcutaneous Electrical Nerve Stimulation in Nerve Regeneration: A Systematic Review of In Vivo Animal Model Studies. Alarcón JB, Chuhuaicura PB, Sluka KA, Vance CGT, Fazan VPS, Godoy KA, Fuentes RE, Dias FJ. Neuromodulation. 2022 Jan 26:S1094-7159(21)06987-7. doi: 10.1016/j.neurom.2021.12.009. PMID: 35088718. Review

Jan 25

Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs. Yu W, Moninger TO, Thurman AL, Xie Y, Jain A, Zarei K, Powers LS, Pezzulo AA, Stoltz DA, Welsh MJ. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2119759119. doi: 10.1073/pnas.2119759119. PMID: 35046051
N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition. Pan R, Kindler E, Cao L, Zhou Y, Zhang Z, Liu Q, Ebert N, Züst R, Sun Y, Gorbalenya AE, Perlman S, Thiel V, Chen Y, Guo D. mBio. 2022 Jan 25:e0366221. doi: 10.1128/mbio.03662-21. PMID: 35073761

Jan 24

Jan 22

2021: The year in review. Ballas ZK. J Allergy Clin Immunol. 2022 Jan 22:S0091-6749(22)00074-4. doi: 10.1016/j.jaci.2022.01.006. PMID: 35077773

Jan 21

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters. Halfmann PJ, Iida S, Iwatsuki-Horimoto K, Maemura T, Kiso M, Scheaffer SM, Darling TL, Joshi A, Loeber S, Singh G, Foster SL, Ying B, Case JB, Chong Z, Whitener B, Moliva J, Floyd K, Ujie M, Nakajima N, Ito M, Wright R, Uraki R, Warang P, Gagne M, Li R, Sakai-Tagawa Y, Liu Y, Larson D, Osorio JE, Hernandez-Ortiz JP, Henry AR, Ciouderis K, Florek KR, Patel M, Odle A, Wong LR, Bateman AC, Wang Z, Edara VV, Chong Z, Franks J, Jeevan T, Fabrizio T, DeBeauchamp J, Kercher L, Seiler P, Gonzalez-Reiche AS, Sordillo EM, Chang LA, van Bakel H, Simon V; Consortium Mount Sinai Pathogen Surveillance (PSP) study group, Douek DC, Sullivan NJ, Thackray LB, Ueki H, Yamayoshi S, Imai M, Perlman S, Webby RJ, Seder RA, Suthar MS, García-Sastre A, Schotsaert M, Suzuki T, Boon ACM, Diamond MS, Kawaoka Y. Nature. 2022 Jan 21. doi: 10.1038/s41586-022-04441-6. PMID: 35062015

Jan 20

Blood-Based Markers of Neuronal Injury in Adult-Onset Myotonic Dystrophy Type 1. van der Plas E, Long JD, Koscik TR, Magnotta V, Monckton DG, Cumming SA, Gottschalk AC, Hefti M, Gutmann L, Nopoulos PC. Front Neurol. 2022 Jan 20;12:791065. doi: 10.3389/fneur.2021.791065. eCollection 2021. PMID: 35126292
Diagnostic delays in infectious diseases. Suneja M, Beekmann SE, Dhaliwal G, Miller AC, Polgreen PM. Diagnosis (Berl). 2022 Jan 20. doi: 10.1515/dx-2021-0092. PMID: 35073468

Jan 19

Associations of state-level and county-level hate crimes with individual-level cardiovascular risk factors in a prospective cohort study of middle-aged Americans: the National Longitudinal Survey of Youths 1979. Gero K, Noubary F, Kawachi I, Baum CF, Wallace RB, Briesacher BA, Kim D. BMJ Open. 2022 Jan 19;12(1):e054360. doi: 10.1136/bmjopen-2021-054360. PMID: 35046003
Features and methods to discriminate between mechanism-based categories of pain experienced in the musculoskeletal system: a Delphi expert consensus study. Shraim MA, Sluka KA, Sterling M, Arendt-Nielsen L, Argoff C, Bagraith KS, Baron R, Brisby H, Carr DB, Chimenti RL, Courtney CA, Curatolo M, Darnall BD, Ford JJ, Graven-Nielsen T, Kolski MC, Kosek E, Liebano RE, Merkle SL, Parker R, Reis FJJ, Smart K, Smeets RJEM, Svensson P, Thompson BL, Treede RD, Ushida T, Williamson OD, Hodges PW. Pain. 2022 Jan 19. doi: 10.1097/j.pain.0000000000002577. PMID: 35319501

Jan 18

Jan 17

Local Factor H production by human choroidal endothelial cells mitigates complement deposition: implications for macular degeneration. Mulfaul K, Mullin NK, Giacalone JC, Voigt AP, DeVore M, Stone EM, Tucker BA, Mullins RF. J Pathol. 2022 Jan 17. doi: 10.1002/path.5867. PMID: 35038170
Measuring hyperemic response to light flicker stimulus using continuous laser speckle flowgraphy in mice. Tamplin MR, Broadhurst KA, Vitale AH, Hashimoto R, Kardon RH, Grumbach IM. Exp Eye Res. 2022 Jan 17;216:108952. doi: 10.1016/j.exer.2022.108952. PMID: 35051429
MCU (Mitochondrial Ca²⁺ Uniporter) makes the calcium go round. Walters GC, Usachev YM. J Biol Chem. 2022 Jan 17:101604. doi: 10.1016/j.jbc.2022.101604. PMID: 35051417

Jan 15

MicroRNA regulation of BAG3. Singh MV, Dhanabalan K, Verry J, Dokun AO. Exp Biol Med (Maywood). 2022 Jan 15:15353702211066908. doi:10.1177/15353702211066908. PMID: 35037515

Jan 14

Care Outcomes for Chiropractic Outpatient Veterans (COCOV): a qualitative study with veteran stakeholders from a pilot trial of multimodal chiropractic care. Salsbury SA, Twist E, Wallace RB, Vining RD, Goertz CM, Long CR. Pilot Feasibility Stud. 2022 Jan 14;8(1):6. doi: 10.1186/s40814-021-00962-5. PMID: 35031072
Gene Therapy Potential for Genetic Disorders of Surfactant Dysfunction. Cooney AL, Wambach JA, Sinn PL, McCray PB Jr. Front Genome Ed. 2022 Jan 14;3:785829. doi: 10.3389/fgeed.2021.785829. eCollection 2021. PMID: 35098209

Jan 13

Advances and gaps in SARS-CoV-2 infection models. Muñoz-Fontela C, Widerspick L, Albrecht RA, Beer M, Carroll MW, de Wit E, Diamond MS, Dowling WE, Funnell SGP, García-Sastre A, Gerhards NM, de Jong R, Munster VJ, Neyts J, Perlman S, Reed DS, Richt JA, Riveros-Balta X, Roy CJ, Salguero FJ, Schotsaert M, Schwartz LM, Seder RA, Segalés J, Vasan SS, Henao-Restrepo AM, Barouch DH. PLoS Pathog. 2022 Jan 13;18(1):e1010161. doi: 10.1371/journal.ppat.1010161. PMID: 35025969
Controlled Hemorrhage Sensitizes Angiotensin II-Elicited Hypertension through Activation of the Brain Renin-Angiotensin System Independently of Endoplasmic Reticulum Stress. Wu GB, Du HB, Zhai JY, Sun S, Cui JL, Zhang Y, Zhao ZA, Wu JL, Johnson AK, Xue B, Zhao ZG, Zhang GS. Oxid Med Cell Longev. 2022 Jan 13;2022:6371048. doi: 10.1155/2022/6371048. eCollection 2022. PMID: 35069977
Peripheral Trigeminal Nerve Blocks for Chronic Orbital Pain: Clinical Features and Outcomes. Lee G, Pham CM, Kardon RH, Shriver EM. Ophthalmic Plast Reconstr Surg. 2022 Jan 13. doi: 10.1097/IOP.0000000000002120. PMID: 35030151

Jan 11

Community-Level Economic Distress, Race, and Risk of Adverse Outcomes After Heart Failure Hospitalization Among Medicare Beneficiaries. Mentias A, Desai MY, Vaughan-Sarrazin MS, Rao S, Morris AA, Hall JL, Menon V, Hockenberry J, Sims M, Fonarow GC, Girotra S, Pandey A. Circulation. 2022 Jan 11;145(2):110-121. doi: 10.1161/CIRCULATIONAHA.121.057756. PMID: 34743555
Development of a national pain management competency profile to guide entry-level physiotherapy education in Canada. Augeard N, Bostick G, Miller J, Walton D, Tousignant-Laflamme Y, Hudon A, Bussières A, Cooper L, McNiven N, Thomas A, Singer L, Fishman SM, Bement MH, Hush JM, Sluka KA, Watt-Watson J, Carlesso LC, Dufour S, Fletcher R, Harman K, Hunter J, Ngomo S, Pearson N, Perreault K, Shay B, Stilwell P, Tupper S, Wideman TH. Can J Pain. 2022 Jan 11;6(1):1-11. doi: 10.1080/24740527.2021.2004103. PMID: 35036823
Loss of the Protective Effect of Estrogen Contributes to Maternal Gestational Hypertension-Induced Hypertensive Response Sensitization Elicited by Postweaning High-Fat Diet in Female Offspring. Xue B, Yu Y, Beltz TG, Guo F, Wei SG, Johnson AK. J Am Heart Assoc. 2022 Jan 11:e023685. doi: 10.1161/JAHA.121.023685. PMID: 35014859
Metabolic Abnormalities in the Basal Ganglia and Cerebellum in Bipolar Disorder: A Multi-modal MR Study. Magnotta VA, Xu J, Fiedorowicz JG, Williams A, Shaffer J, Christensen G, Long JD, Taylor E, Sathyaputri L, Richards JG, Harmata G, Wemmie J J Affect Disord. 2022 Jan 11:S0165-0327(22)00056-8. doi: 10.1016/j.jad.2022.01.052. PMID: 35031333

Jan 10

Azole-resistant alleles of ERG11 in Candida glabrata trigger activation of the Pdr1 and Upc2A transcription factors. Vu BG, Moye-Rowley WS. Antimicrob Agents Chemother. 2022 Jan 10:AAC0209821. doi: 10.1128/AAC.02098-21. PMID: 35007132
Genes that Escape X Chromosome Inactivation Modulate Sex Differences in Valve Myofibroblasts. Aguado BA, Walker CJ, Grim JC, Schroeder ME, Batan D, Vogt BJ, Gonzalez Rodriguez A, Schwisow JA, Moulton KS, Weiss RM, Heistad DD, Leinwand LA, Anseth KS. Circulation. 2022 Jan 10. doi: 10.1161/CIRCULATIONAHA.121.054108. PMID: 35000411

Jan 7

Biomarkers for Components of Dietary Protein and Carbohydrate with Application to Chronic Disease Risk Among Postmenopausal Women. Prentice RL, Pettinger M, Zheng C, Neuhouser ML, Raftery D, Gowda GAN, Huang Y, Tinker LF, Howard BV, Manson JE, Van Horn L, Wallace R, Mossavar-Rahmani Y, Johnson KC, Snetselaar L, Lampe JW. J Nutr. 2022 Jan 7:nxac004. doi: 10.1093/jn/nxac004. PMID: 35015878

Jan 6

Unresolved questions in the zoonotic transmission of MERS. Peiris M, Perlman S. Curr Opin Virol. 2022 Jan 6;52:258-264. doi: 10.1016/j.coviro.2021.12.013. PMID: 34999369 Review.

Jan 5

AAV-mediated gene editing lights up the lung. Yan Z, Lynch TJ, Engelhardt JF. Mol Ther. 2022 Jan 5;30(1):7-9. doi: 10.1016/j.ymthe.2021.12.003. Epub 2021 Dec 10. PMID: 34895514
Resuscitation Using ECPR During In-Hospital Cardiac Arrest (RESCUE-IHCA) Mortality Prediction Score and External Validation. Tonna JE, Selzman CH, Girotra S, Presson AP, Thiagarajan RR, Becker LB, Zhang C, Rycus P, Keenan HT; American Heart Association Get With the Guidelines–Resuscitation Investigators. JACC Cardiovasc Interv. 2022 Jan 5:S1936-8798(21)01817-3. doi:10.1016/j.jcin.2021.09.032. PMID: 35033471

Jan 4

Effectiveness of a Novel ω-3 Krill Oil Agent in Patients With Severe Hypertriglyceridemia: A Randomized Clinical Trial. Mozaffarian D, Maki KC, Bays HE, Aguilera F, Gould G, Hegele RA, Moriarty PM, Robinson JG, Shi P, Tur JF, Lapointe JF, Aziz S, Lemieux P; TRILOGY (Study of CaPre in Lowering Very High Triglycerides) investigators. JAMA Netw Open. 2022 Jan 4;5(1):e2141898. doi: 10.1001/jamanetworkopen.2021.41898. PMID: 34989797
Inter-individual Variation in Receptor Expression Influences MERS-CoV Infection and Immune Responses in Airway Epithelia. Li K, Wohlford-Lenane C, Bartlett JA, McCray PB Jr. Front Public Health. 2022 Jan 4;9:756049. doi: 10.3389/fpubh.2021.756049. eCollection 2021. PMID: 35059374
Quantification of uptake in pelvis F-18 FLT PET-CT images using a 3D localization and segmentation CNN. Xiong X, Smith BJ, Graves SA, Sunderland JJ, Graham MM, Gross BA, Buatti JM, Beichel RR. Med Phys. 2022 Jan 4. doi: 10.1002/mp.15440. PMID: 34982836
Research-Relevant Conditions and Pathology of Laboratory Mice, Rats, Gerbils, Guinea Pigs, Hamsters, Naked Mole Rats, and Rabbits. Cooper TK, Meyerholz DK, Beck AP, Delaney MA, Piersigilli A, Southard TL, Brayton CF. ILAR J. 2022 Jan 4:ilab022. doi: 10.1093/ilar/ilab022. PMID: 34979559

Jan 1

February 2022

Feb 28

Novel CALM3 Variant Causing Calmodulinopathy With Variable Expressivity in a 4-Generation Family. Kato K, Isbell HM, Fressart V, Denjoy I, Debbiche A, Itoh H, Poinsot J, George AL Jr, Coulombe A, Shea MA, Guicheney P. Circ Arrhythm Electrophysiol. 2022 Feb 28:CIRCEP121010572. doi: 10.1161/CIRCEP.121.010572. PMID: 35225649

Feb 25

Neutrophil Dysfunction in the Pathogenesis of Cystic Fibrosis. Wang G, Nauseef WM. Blood. 2022 Feb 25:blood.2021014699. doi: 10.1182/blood.2021014699. PMID: 35213685

Feb 24

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Barc J, Tadros R, Glinge C, Chiang DY, Jouni M, Simonet F, Jurgens SJ, Baudic M, Nicastro M, Potet F, Offerhaus JA, Walsh R, Choi SH, Verkerk AO, Mizusawa Y, Anys S, Minois D, Arnaud M, Duchateau J, Wijeyeratne YD, Muir A, Papadakis M, Castelletti S, Torchio M, Ortuño CG, Lacunza J, Giachino DF, Cerrato N, Martins RP, Campuzano O, Van Dooren S, Thollet A, Kyndt F, Mazzanti A, Clémenty N, Bisson A, Corveleyn A, Stallmeyer B, Dittmann S, Saenen J, Noël A, Honarbakhsh S, Rudic B, Marzak H, Rowe MK, Federspiel C, Le Page S, Placide L, Milhem A, Barajas-Martinez H, Beckmann BM, Krapels IP, Steinfurt J, Winkel BG, Jabbari R, Shoemaker MB, Boukens BJ, Škorić-Milosavljević D, Bikker H, Manevy FC, Lichtner P, Ribasés M, Meitinger T, Müller-Nurasyid M; KORA-Study Group, Veldink JH, van den Berg LH, Van Damme P, Cusi D, Lanzani C, Rigade S, Charpentier E, Baron E, Bonnaud S, Lecointe S, Donnart A, Le Marec H, Chatel S, Karakachoff M, Bézieau S, London B, Tfelt-Hansen J, Roden D, Odening KE, Cerrone M, Chinitz LA, Volders PG, van de Berg MP, Laurent G, Faivre L, Antzelevitch C, Kääb S, Arnaout AA, Dupuis JM, Pasquie JL, Billon O, Roberts JD, Jesel L, Borggrefe M, Lambiase PD, Mansourati J, Loeys B, Leenhardt A, Guicheney P, Maury P, Schulze-Bahr E, Robyns T, Breckpot J, Babuty D, Priori SG, Napolitano C; Nantes Referral Center for inherited cardiac arrhythmia, de Asmundis C, Brugada P, Brugada R, Arbelo E, Brugada J, Mabo P, Behar N, Giustetto C, Molina MS, Gimeno JR, Hasdemir C, Schwartz PJ, Crotti L, McKeown PP, Sharma S, Behr ER, Haissaguerre M, Sacher F, Rooryck C, Tan HL, Remme CA, Postema PG, Delmar M, Ellinor PT, Lubitz SA, Gourraud JB, Tanck MW, George AL Jr, MacRae CA, Burridge PW, Dina C, Probst V, Wilde AA, Schott JJ, Redon R, Bezzina CR. Nat Genet. 2022 Feb 24. doi: 10.1038/s41588-021-01007-6. PMID: 35210625
γ Peptide Nucleic Acid-Based miR-122 Inhibition Rescues Vascular Endothelial Dysfunction in Mice Fed a High-Fat Diet. Gaddam RR, Dhuri K, Kim YR, Jacobs JS, Kumar V, Li Q, Irani K, Bahal R, Vikram A. J Med Chem. 2022 Feb 24;65(4):3332-3342. doi: 10.1021/acs.jmedchem.1c01831. PMID: 35133835

Feb 23

Aspergillus fumigatus ffmA Encodes a C₂H₂-Containing Transcriptional Regulator That Modulates Azole Resistance and Is Required for Normal Growth. Paul S, Bowyer P, Bromley M, Moye-Rowley WS. mSphere. 2022 Feb 23;7(1):e0093821. doi: 10.1128/msphere.00938-21. PMID: 35138125
Obesity induces resistance to central action of BMP8B through a mechanism involving the BBSome. Rial-Pensado E, Freire-Agulleiro O, Ríos M, Guo DF, Contreras C, Seoane-Collazo P, Tovar S, Nogueiras R, Diéguez C, Rahmouni K, López M. Mol Metab. 2022 Feb 23:101465. doi: 10.1016/j.molmet.2022.101465. PMID: 35218946
Origins of and lessons from quantitative functional X-Ray computed tomography of the lung. Hoffman EA. Br J Radiol. 2022 Feb 23:20211364. doi: 10.1259/bjr.20211364. PMID: 35193364 Review.

Feb 22

Approaches to Healthcare Personnel Exemption Requests from COVID Vaccination: Results of a National Survey. Talbot TR, Beekmann SE, Babcock HM, Polgreen PM. Infect Control Hosp Epidemiol. 2022 Feb 22:1-22. doi: 10.1017/ice.2022.47. PMID: 35190002
Histamine H₂ Receptor Antagonists and Heart Failure Risk in Postmenopausal Women: The Women's Health Initiative. Larson SR, Vasbinder AL, Reding KW, Leary PJ, Branch KR, Shadyab AH, Johnson KC, Haring B, Wallace R, Manson JE, Anderson G, Cheng RK. J Am Heart Assoc. 2022 Feb 22:e024270. doi: 10.1161/JAHA.121.024270. PMID: 35191329

Feb 21

Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency. De La Rossa A, Laporte MH, Astori S, Marissal T, Montessuit S, Sheshadri P, Ramos-Fernández E, Mendez P, Khani A, Quairiaux C, Taylor EB, Rutter J, Nunes JM, Carleton A, Duchen MR, Sandi C, Martinou JC. Elife. 2022 Feb 21;11:e72595. doi: 10.7554/eLife.72595. PMID: 35188099

Feb 19

Choroidal Endothelial and Macrophage Gene Expression in Atrophic and Neovascular Macular Degeneration. Voigt AP, Mullin NK, Mulfaul K, Lozano LP, Wiley LA, Flamme-Wiese MJ, Boese EA, Han IC, Scheetz TE, Stone EM, Tucker BA, Mullins RF. Hum Mol Genet. 2022 Feb 19:ddac043. doi: 10.1093/hmg/ddac043. PMID: 35181781
Non-invasive localization of premature ventricular focus: A prospective multicenter study. Chrispin J, Mazur A, Winterfield J, Nazeri A, Valderrabano M, Tandri H. J Electrocardiol. 2022 Feb 19;72:6-12. doi: 10.1016/j.jelectrocard.2022.02.007. PMID: 35220047

Feb 18

Ankle- and Toe-Brachial Index for Peripheral Artery Disease Identification: Unlocking Clinical Data Through Novel Methods. Friberg JE, Qazi AH, Boyle B, Franciscus C, Vaughan-Sarrazin M, Westerman D, Patterson OV, Parr SK, Matheny ME, Arya S, Smolderen KG, Lund BC, Gobbel GT, Girotra S. Circ Cardiovasc Interv. 2022 Feb 18: CIRCINTERVENTIONS121011092. doi: 10.1161/CIRCINTERVENTIONS.121.011092. PMID: 35176872

Feb 17

Professionalism of Admitting and Consulting Services and Trauma Patient Outcomes. Cooper WO, Hickson GB, Guillamondegui OD, Cannon JW, Charles AG, Hoth JJ, Alam HB, Tillou A, Luchette FA, Skeete DA, Domenico HJ, Meredith JW, Brennan TMH, Smith BP, Kelz RR, Biesterveld BE, Busuttil A, Jopling JK, Hopkins JR, Emory CL, Sullivan PG, Martin RS, Howerton RM, Cryer HM, Davidson HA, Gonzalez RP, Spain DA. Ann Surg. 2022 Feb 17. doi: 10.1097/SLA.0000000000005416. PMID: 35185124
Voluntary Exercise Prevents Hypertensive Response Sensitization Induced by Angiotensin II. Xue B, Cui JL, Guo F, Beltz TG, Zhao ZG, Zhang GS, Johnson AK. Front Neurosci. 2022 Feb 17;16:848079. doi: 10.3389/fnins.2022.848079. PMID: 35250473

Feb 16

Producing personalized statin treatment plans to optimize clinical outcomes using big data and machine learning. Chi CL, Wang J, Ying Yew P, Lenskaia T, Loth M, Mani Pradhan P, Liang Y, Kurella P, Mehta R, Robinson JG, Tonellato PJ, Adam TJ. J Biomed Inform. 2022 Feb 16:104029. doi: 10.1016/j.jbi.2022.104029. PMID: 35182785

Feb 15

Genes That Escape X Chromosome Inactivation Modulate Sex Differences in Valve Myofibroblasts. Aguado BA, Walker CJ, Grim JC, Schroeder ME, Batan D, Vogt BJ, Rodriguez AG, Schwisow JA, Moulton KS, Weiss RM, Heistad DD, Leinwand LA, Anseth KS. Circulation. 2022 Feb 15;145(7):513-530. doi: 10.1161/CIRCULATIONAHA.121.054108. PMID: 35000411
Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability. Teekakirikul P, Zhu W, Xu X, Young CB, Tan T, Smith AM, Wang C, Peterson KA, Gabriel GC, Ho S, Sheng Y, Moreau de Bellaing A, Sonnenberg DA, Lin JH, Fotiou E, Tenin G, Wang MX, Wu YL, Feinstein T, Devine W, Gou H, Bais AS, Glennon BJ, Zahid M, Wong TC, Ahmad F, Rynkiewicz MJ, Lehman WJ, Keavney B, Alastalo TP, Freckmann ML, Orwig K, Murray S, Ware SM, Zhao H, Feingold B, Lo CW. Cell Rep Med. 2022 Feb 15;3(2):100501. doi: 10.1016/j.xcrm.2021.100501. PMID: 35243414

Feb 14

Clinical and neuroradiological correlates of sleep in myotonic dystrophy type 1. Hamilton MJ, Atalaia A, McLean J, Cumming SA, Evans JJ, Ballantyne B, Jampana R, The Scottish Myotonic Dystrophy Consortium, Longman C, Livingston E, van der Plas E, Koscik T, Nopoulos P, Farrugia ME, Monckton DG. Neuromuscul Disord. 2022 Feb 14:S0960-8966(22)00036-0. doi: 10.1016/j.nmd.2022.02.003. PMID: 35361525
Intron Mutations and Early Transcription Termination in Duchenne and Becker muscular dystrophy. Waldrop MA, Moore SA, Mathews KD, Darbro BW, Medne L, Finkel R, Connolly AM, Crawford TO, Drachman D, Wein N, Habib AA, Krzesniak-Swinarska MA, Zaidman CM, Collins JJ, Jokela M, Udd B, Day JW, Ortiz-Guerrero G, Statland J, Butterfield RJ, Dunn DM, Weiss RB, Flanigan KM. Hum Mutat. 2022 Feb 14. doi: 10.1002/humu.24343. PMID: 35165973
Resuscitation Using ECPR During In-Hospital Cardiac Arrest (RESCUE-IHCA) Mortality Prediction Score and External Validation. Tonna JE, Selzman CH, Girotra S, Presson AP, Thiagarajan RR, Becker LB, Zhang C, Rycus P, Keenan HT; American Heart Association Get With the Guidelines–Resuscitation Investigators. JACC Cardiovasc Interv. 2022 Feb 14;15(3):237-247. doi: 10.1016/j.jcin.2021.09.032. PMID: 35033471

Feb 12

Modulation of miR-181 influences dopaminergic neuronal degeneration in a mouse model of Parkinson's disease. Stein CS, McLendon JM, Witmer NH, Boudreau RL. Mol Ther Nucleic Acids. 2022 Feb 12;28:1-15. doi: 10.1016/j.omtn.2022.02.007. PMID: 35280925

Feb 11

Perceptions of risk of SARS-CoV-2 transmission in social and educational activities by infectious diseases and general pediatric healthcare providers, a pre-vaccine risk perception cross-sectional survey. Janowski AB, Polgreen PM, Beekmann SE, Newland JG.PLoS One. 2022 Feb 11;17(2):e0263767. doi: 10.1371/journal.pone.0263767. eCollection 2022. PMID: 35148344
Rural-urban differences in secular trends of locoregional treatment for ductal carcinoma in situ: A patterns of care analysis. Riley D, Chrischilles EA, Lizarraga IM, Charlton M, Smith BJ, Lynch CF. Cancer Med. 2022 Feb 11. doi: 10.1002/cam4.4605. PMID: 3514694

Feb 10

Feb 9

Aspergillus fumigatus ffmA Encodes a C₂H₂-Containing Transcriptional Regulator That Modulates Azole Resistance and Is Required for Normal Growth. Paul S, Bowyer P, Bromley M, Moye-Rowley WS. mSphere. 2022 Feb 9:e0093821. doi: 10.1128/msphere.00938-21. PMID: 35138125
Development of a Single-Cycle Infectious SARS-CoV-2 Virus Replicon Particle System for Use in Biosafety Level 2 Laboratories. Malicoat J, Manivasagam S, Zuñiga S, Sola I, McCabe D, Rong L, Perlman S, Enjuanes L, Manicassamy B. J Virol. 2022 Feb 9;96(3):e0183721. doi: 10.1128/JVI.01837-21. PMID: 34851142
Increased interstage morbidity and mortality following stage 1 palliation in patients with genetic abnormalities. Pierick AR, Pierick TA, Scholz TD, Zimmerman MB, Reinking BE. Cardiol Young. 2022 Feb 9:1-6. doi: 10.1017/S1047951122000166. PMID: 35137681

Feb 8

The inflammatory pathology of dysferlinopathy is distinct from calpainopathy, Becker muscular dystrophy, and inflammatory myopathies. Becker N, Moore SA, Jones KA. Acta Neuropathol Commun. 2022 Feb 8;10(1):17. doi: 10.1186/s40478-022-01320-z. PMID: 35135626
γ Peptide Nucleic Acid-Based miR-122 Inhibition Rescues Vascular Endothelial Dysfunction in Mice Fed a High-Fat Diet. Gaddam RR, Dhuri K, Kim YR, Jacobs JS, Kumar V, Li Q, Irani K, Bahal R, Vikram A. J Med Chem. 2022 Feb 8. doi: 10.1021/acs.jmedchem.1c01831. PMID: 35133835

Feb 7

Umbilical Cord Blood Leptin and IL-6 in the Presence of Maternal Diabetes or Chorioamnionitis. Vasilakos LK, Steinbrekera B, Santillan DA, Santillan MK, Brandt DS, Dagle D, Roghair RD. Front Endocrinol (Lausanne). 2022 Feb 7;13:836541. doi: 10.3389/fendo.2022.836541. eCollection 2022. PMID: 35197933

Feb 4

Cross-sectional, Neuromuscular Phenotyping Study of Arhinia Patients With SMCHD1 Variants. Mohassel P, Chang N, Inoue K, Delaney A, Hu Y, Donkervoort S, Saade D, Billioux BJ, Meader B, Volochayev R, Konersman CG, Kaindl AM, Cho CH, Russell B, Rodriguez A, Foster KW, Foley AR, Moore SA, Jones PL, Bonnemann CG, Jones T, Shaw ND. Neurology. 2022 Feb 4:10.1212/WNL.0000000000200032. doi: 10.1212/WNL.0000000000200032. PMID: 35121673

Feb 2

Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort. Ronish BE, Couper DJ, Barjaktarevic IZ, Cooper CB, Kanner RE, Pirozzi CS, Kim V, Wells JM, Han MK, Woodruff PG, Ortega VE, Peters SP, Hoffman EA, Buhr RG, Dolezal BA, Tashkin DP, Liou TG, Bateman LA, Schroeder JD, Martinez FJ, Barr RG, Hansel NN, Comellas AP, Rennard SI, Arjomandi M, Paine Iii R. Chronic Obstr Pulm Dis. 2022 Feb 2. doi: 10.15326/jcopdf.2021.0241. PMID: 35114743

Feb 1

March 2022

March 31

Defining the risk of SARS-CoV-2 variants on immune protection. DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, Alisoltani A, Alter G, Amara RR, Baric RS, Barouch DH, Bloom JD, Bloyet LM, Bonenfant G, Boon ACM, Boritz EA, Bratt DL, Bricker TL, Brown L, Buchser WJ, Carreño JM, Cohen-Lavi L, Darling TL, Davis-Gardner ME, Dearlove BL, Di H, Dittmann M, Doria-Rose NA, Douek DC, Drosten C, Edara VV, Ellebedy A, Fabrizio TP, Ferrari G, Florence WC, Fouchier RAM, Franks J, García-Sastre A, Godzik A, Gonzalez-Reiche AS, Gordon A, Haagmans BL, Halfmann PJ, Ho DD, Holbrook MR, Huang Y, James SL, Jaroszewski L, Jeevan T, Johnson RM, Jones TC, Joshi A, Kawaoka Y, Kercher L, Koopmans MPG, Korber B, Koren E, Koup RA, LeGresley EB, Lemieux JE, Liebeskind MJ, Liu Z, Livingston B, Logue JP, Luo Y, McDermott AB, McElrath MJ, Meliopoulos VA, Menachery VD, Montefiori DC, Mühlemann B, Munster VJ, Munt JE, Nair MS, Netzl A, Niewiadomska AM, O'Dell S, Pekosz A, Perlman S, Pontelli MC, Rockx B, Rolland M, Rothlauf PW, Sacharen S, Scheuermann RH, Schmidt SD, Schotsaert M, Schultz-Cherry S, Seder RA, Sedova M, Sette A, Shabman RS, Shen X, Shi PY, Shukla M, Simon V, Stumpf S, Sullivan NJ, Thackray LB, Theiler J, Thomas PG, Trifkovic S, Türeli S, Turner SA, Vakaki MA, van Bakel H, VanBlargan LA, Vincent LR, Wallace ZS, Wang L, Wang M, Wang P, Wang W, Weaver SC, Webby RJ, Weiss CD, Wentworth DE, Weston SM, Whelan SPJ, Whitener BM, Wilks SH, Xie X, Ying B, Yoon H, Zhou B, Hertz T, Smith DJ, Diamond MS, Post DJ, Suthar MS. Nature. 2022 Mar 31. doi: 10.1038/s41586-022-04690-5. PMID: 35361968. Review.
Dural Immune Cells, CGRP, and Migraine. Balcziak LK, Russo AF. Front Neurol. 2022 Mar 31;13:874193. doi: 10.3389/fneur.2022.874193. PMID: 35432179

March 30

Risk factors for hemolysis with centrifugal pumps in pediatric extracorporeal membrane oxygenation: Is pump replacement an answer? Chu JH, Sarathy S, Ramesh S, Rudolph K, Raghavan ML, Badheka A. Perfusion. 2022 Mar 30:2676591221082499. doi: 10.1177/02676591221082499. PMID: 35354417
The voltage-gated Ca2+ channel subunit α2δ-4 regulates locomotor behavior and sensorimotor gating in mice. Klomp A, Omichi R, Iwasa Y, Smith RJ, Usachev YM, Russo AF, Narayanan NS, Lee A. PLoS One. 2022 Mar 30;17(3):e0263197. doi: 10.1371/journal.pone.0263197. eCollection 2022. PMID: 35353835

March 29

Cross-sectional Neuromuscular Phenotyping Study of Patients With Arhinia With SMCHD1 Variants. Mohassel P, Chang N, Inoue K, Delaney A, Hu Y, Donkervoort S, Saade D, Billioux BJ, Meader B, Volochayev R, Konersman CG, Kaindl AM, Cho CH, Russell B, Rodriguez A, Foster KW, Foley AR, Moore SA, Jones PL, Bonnemann CG, Jones T, Shaw ND. Neurology. 2022 Mar 29;98(13):e1384-e1396. doi: 10.1212/WNL.0000000000200032. PMID: 35121673
Elastic mucus strands impair mucociliary clearance in cystic fibrosis pigs. Pino-Argumedo MI, Fischer AJ, Hilkin BM, Gansemer ND, Allen PD, Hoffman EA, Stoltz DA, Welsh MJ, Abou Alaiwa MH. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2121731119. doi: 10.1073/pnas.2121731119. PMID: 35324331

March 28

Blocking Gi/o-Coupled Signaling Eradicates Cancer Stem Cells and Sensitizes Breast Tumors to HER2-Targeted Therapies to Inhibit Tumor Relapse. Lyu C, Ye Y, Weigel RJ, Chen S. Cancers (Basel). 2022 Mar 28;14(7):1719. doi: 10.3390/cancers14071719. PMID: 35406489
Clinical features and outcomes of patients in different age groups with non-valvular atrial fibrillation receiving oral anticoagulants. O UF, Chong TK, Wei Y, Paudel B, Giudici MC, Wong CW, Lei WK, Chen J, Wu W, Liu K. Int J Cardiol Heart Vasc. 2022 Mar 28;40:101009. doi: 10.1016/j.ijcha.2022.101009. PMID: 35372665

March 26

The 2022 AAAAI Foundation Faculty Development awardees. Ballas ZK. J Allergy Clin Immunol. 2022 Mar 26:S0091-6749(22)00384-0. doi: 10.1016/j.jaci.2022.03.012. PMID: 35351440

March 25

Longitudinal optical coherence tomography angiography (OCT-A) in a patient with radiation retinopathy following plaque brachytherapy for uveal melanoma. Binkley EM, Tamplin MR, Vitale AH, Boldt HC, Kardon RH, Grumbach IM. Am J Ophthalmol Case Rep. 2022 Mar 25;26:101508. doi: 10.1016/j.ajoc.2022.101508. PMID: 35392251

March 24

Resistance training protects against muscle pain through activation of androgen receptors in male and female mice. Lesnak JB, Fahrion A, Helton A, Rasmussen L, Andrew M, Cunard S, Huey M, Kreber A, Landon J, Siwiec T, Todd K, Frey-Law LA, Sluka KA. Pain. 2022 Mar 24. doi: 10.1097/j.pain.0000000000002638. PMID: 35353765
Translating outcomes from the clinical setting to preclinical models: chronic pain and functionality in chronic musculoskeletal pain. Lenert ME, Gomez R, Lane BT, Dailey DL, Vance CGT, Rakel BA, Crofford LJ, Sluka KA, Merriwether EN, Burton MD. Pain Med. 2022 Mar 24:pnac047. doi: 10.1093/pm/pnac047. PMID: 35325207

March 23

Angiotensin II Inhibits the A-type K⁺ Current of Hypothalamic Paraventricular Nucleus Neurons in Rats with Heart Failure: Role of MAPK-ERK1/2 Signaling. Roy RK, Ferreira-Neto HC, Felder RB, Stern JE. Am J Physiol Regul Integr Comp Physiol. 2022 Mar 23. doi: 10.1152/ajpregu.00308.2021. PMID: 35319903
Gene Therapy With the N-Terminus of Junctophilin-2 Improves Heart Failure in Mice. Wang J, Shi Q, Wang Y, Dawson LW, Ciampa G, Zhao W, Zhang G, Chen B, Weiss RM, Grueter CE, Hall DD, Song LS. Circ Res. 2022 Mar 23:CIRCRESAHA121320680. doi: 10.1161/CIRCRESAHA.121.320680. PMID: 35317607

March 21

Eicosanoid signaling blockade protects middle-aged mice from severe COVID-19. Wong LR, Zheng J, Wilhelmsen K, Li K, Ortiz ME, Schnicker NJ, Thurman A, Pezzulo AA, Szachowicz PJ, Li P, Pan R, Klumpp K, Aswad F, Rebo J, Narumiya S, Murakami M, Zuniga S, Sola I, Enjuanes L, Meyerholz DK, Fortney K, McCray PB Jr, Perlman S. Nature. 2022 Mar 21. doi: 10.1038/s41586-022-04630-3. PMID: 35314834
The Graded Prognostic Assessment (GPA) for Lung Cancer Patients with Brain Metastases: Initial Report of the Small Cell Lung Cancer GPA and Update of the Non-Small Cell Lung Cancer GPA including the Effect of Programmed Death Ligand-1 (PD-L1) and Other Prognostic Factors. Sperduto PW, De B, Li J, Carpenter D, Kirkpatrick J, Milligan M, Shih HA, Kutuk T, Kotecha R, Higaki H, Otsuka M, Aoyama H, Bourgoin M, Roberge D, Dajani S, Sachdev S, Gainey J, Buatti JM, Breen W, Brown PD, Ni L, Braunstein S, Gallitto M, Wang TJC, Shanley R, Lou E, Shiao J, Gaspar LE, Tanabe S, Nakano T, An Y, Chiang V, Zeng L, Soliman H, Elhalawani H, Cagney D, Thomas E, Boggs DH, Ahluwalia MS, Mehta MP. Int J Radiat Oncol Biol Phys. 2022 Mar 21:S0360-3016(22)00253-X. doi: 10.1016/j.ijrobp.2022.03.020. PMID: 35331827
Lipid nanoparticle-mRNA: another step in the fight against COVID-19. Verma AK, Perlman S.Cell Res. 2022 Mar 21. doi: 10.1038/s41422-022-00647-5. PMID: 35314770

March 19

Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR. Belz DC, Woo H, Putcha N, Paulin LM, Koehler K, Fawzy A, Alexis NE, Barr RG, Comellas AP, Cooper CB, Couper D, Dransfield M, Gassett AJ, Han M, Hoffman EA, Kanner RE, Krishnan JA, Martinez FJ, Paine R 3rd, Peng RD, Peters S, Pirozzi CS, Woodruff PG, Kaufman JD, Hansel NN; SPIROMICS Investigators. Sci Total Environ. 2022 Mar 19:154694. doi: 10.1016/j.scitotenv.2022.154694. PMID: 35318050
Cardiorespiratory Fitness in Adults Aged 18 to 34 Years and Long-Term Pericardial Adipose Tissue (from the Coronary Artery Risk Development in Young Adults Study). Oh M, Gabriel KP, Jacobs DR Jr, Bao W, Pierce GL, Carr LJ, Terry JG, Ding J, Carr JJ, Whitaker KM. Am J Cardiol. 2022 Mar 19:S0002-9149(22)00186-2. doi: 10.1016/j.amjcard.2022.02.031. PMID: 35317931

March 18

A Novel Bioreactor for Reconstitution of the Epithelium and Submucosal Glands in Decellularized Ferret Tracheas. Pai AC, Lynch TJ, Ahlers BA, Ievlev V, Engelhardt JF, Parekh KR. Cells. 2022 Mar 18;11(6):1027. doi: 10.3390/cells11061027. PMID: 35326478

March 17

Oxidation of ferumoxytol by ionizing radiation releases iron. An electron paramagnetic resonance study. Petronek MS, Spitz DR, Buettner GR, Allen BG. J Radiat Res. 2022 Mar 17:rrac008. doi: 10.1093/jrr/rrac008. PMID: 35301531
Pathogen Stimulation of Interleukin-8 from Human Vaginal Epithelial Cells through CD40. Schlievert PM, Kilgore SH, Benavides A, Klingelhutz AJ. Microbiol Spectr. 2022 Mar 17:e0010622. doi: 10.1128/spectrum.00106-22. PMID: 35297656

March 16

Clinical Implementational and Site-Specific Workflows for a 1.5T MR-Linac. Dunkerley DAP, Hyer DE, Snyder JE, St-Aubin JJ, Anderson CM, Caster JM, Smith MC, Buatti JM, Yaddanapudi S. J Clin Med. 2022 Mar 16;11(6):1662. doi: 10.3390/jcm11061662. PMID: 35329988

March 15

Azole-Resistant Alleles of ERG11 in Candida glabrata Trigger Activation of the Pdr1 and Upc2A Transcription Factors. Vu BG, Moye-Rowley WS. Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0209821. doi: 10.1128/AAC.02098-21. PMID: 35007132
Metabolic abnormalities in the basal ganglia and cerebellum in bipolar disorder: A multi-modal MR study. Magnotta VA, Xu J, Fiedorowicz JG, Williams A, Shaffer J, Christensen G, Long JD, Taylor E, Sathyaputri L, Richards JG, Harmata G, Wemmie J. J Affect Disord. 2022 Mar 15;301:390-399. doi: 10.1016/j.jad.2022.01.052. PMID: 35031333
Quantitative Chest CT Assessment of Small Airways Disease in Post-Acute SARS-CoV-2 Infection. Cho JL, Villacreses R, Nagpal P, Guo J, Pezzulo AA, Thurman AL, Hamzeh NY, Blount RJ, Fortis S, Hoffman EA, Zabner J, Comellas AP. Radiology. 2022 Mar 15:212170. doi: 10.1148/radiol.212170. PMID: 35289657

March 12

The Influence of Opioids on Transcutaneous Electrical Nerve Stimulation Effects in Women with Fibromyalgia. Dailey DL, Vance CG, Chimenti R, Rakel BA, Zimmerman MB, Williams JM, Sluka KA, Crofford LJ. J Pain. 2022 Mar 12:S1526-5900(22)00046-3. doi: 10.1016/j.jpain.2022.02.008. PMID: 35292378
Turoctocog alfa pegol (N8-GP) in severe hemophilia A: Long-term safety and efficacy in previously treated patients of all ages in the pathfinder8 study. Lentz SR, Kavakli K, Klamroth R, Misgav M, Nagao A, Tosetto A, Jørgensen PJ, Zak M, Nemes L. Res Pract Thromb Haemost. 2022 Mar 12;6(2):e12674. doi: 10.1002/rth2.12674. PMID: 35308099

March 8

Ferret models of alpha-1 antitrypsin deficiency develop lung and liver disease. He N, Liu X, Vegter AR, Evans TIA, Gray JS, Guo J, Moll SR, Guo LJ, Luo M, Ma N, Sun X, Liang B, Yan Z, Feng Z, Qi L, Joshi AS, Shahin W, Yi Y, Gibson-Corley KN, Hoffman EA, Wang K, Mueller C, Engelhardt JF, Rosen BH. JCI Insight. 2022 Mar 8;7(5):e143004. doi: 10.1172/jci.insight.143004. PMID: 35104244

March 7

Care Outcomes for Chiropractic Outpatient Veterans (COCOV):a single-arm, pragmatic, pilot trial of multimodal chiropractic care for U.S. veterans with chronic low back pain. Long CR, Salsbury SA, Vining RD, Lisi AJ, Corber L, Twist E, Abrams T, Wallace RB, Goertz CM. Pilot Feasibility Stud. 2022 Mar 7;8(1):54. doi: 10.1186/s40814-022-01008-0. PMID: 35256010
Cortical Features in Child and Adolescent Carriers of Mutant Huntingtin (mHTT). Reasoner EE, van der Plas E, Langbehn DR, Conrad AL, Koscik TR, Epping EA, Magnotta VA, Nopoulos PC. J Huntingtons Dis. 2022 Mar 7. doi: 10.3233/JHD-210512. PMID: 35275555

March 6

Prevalence and Risk Factors of Poor Sleep Quality in Collegiate Athletes during COVID-19 Pandemic: A Cross-Sectional Study. Melone MA, Tourny C, Gehlbach BK, Schmidt EL, Lalevée M, L'Hermette M. Int J Environ Res Public Health. 2022 Mar 6;19(5):3098. doi: 10.3390/ijerph19053098. PMID: 35270790

March 3

Lysosomes and the pathogenesis of merosin-deficient congenital muscular dystrophy. Smith SJ, Fabian L, Sheikh A, Noche R, Cui X, Moore SA, Dowling JJ. Hum Mol Genet. 2022 Mar 3;31(5):733-747. doi: 10.1093/hmg/ddab278. PMID: 34568901
Sensitive quantification of m.3243A>G mutational proportion in non-retinal tissues and its relationship with visual symptoms. Mullin NK, Anfinson KR, Riker MJ, Wieland KL, Tatro NJ, Scheetz TE, Mullins RF, Stone EM, Tucker BA. Hum Mol Genet. 2022 Mar 3;31(5):775-782. doi: 10.1093/hmg/ddab289. PMID: 34590675

March 2

A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis. Thurman AL, Li X, Villacreses R, Yu W, Gong H, Mather SE, Romano-Ibarra GS, Meyerholz DK, Stoltz DA, Welsh MJ, Thornell IM, Zabner J, Pezzulo AA. Am J Respir Cell Mol Biol. 2022 Mar 2. doi: 10.1165/rcmb.2021-0499OC. PMID: 35235762

March 1

April 2022

April 29

Evidence-based intraoperative infection control measures plus feedback are associated with attenuation of severe acute respiratory syndrome coronavirus-2 detection in operating rooms. Loftus RW, Dexter F, Evans L, Robinson A, Odle A, Perlman S. Br J Anaesth. 2022 Apr 29:S0007-0912(22)00200-8. doi: 10.1016/j.bja.2022.04.018. PMID: 35643533
Gene Therapy With the N-Terminus of Junctophilin-2 Improves Heart Failure in Mice. Wang J, Shi Q, Wang Y, Dawson LW, Ciampa G, Zhao W, Zhang G, Chen B, Weiss RM, Grueter CE, Hall DD, Song LS. Circ Res. 2022 Apr 29;130(9):1306-1317. doi: 10.1161/CIRCRESAHA.121.320680. PMID: 35317607
Myeloid Cell PKM2 Deletion Enhances Efferocytosis and Reduces Atherosclerosis. Doddapattar P, Dev R, Ghatge M, Patel RB, Jain M, Dhanesha N, Lentz SR, Chauhan AK. Circ Res. 2022 Apr 29;130(9):1289-1305. doi: 10.1161/CIRCRESAHA.121.320704. PMID: 35400205

April 28

Association Between Cardiorespiratory Fitness and Cerebrovascular Reactivity to a Breath Hold Stimulus in Older Adults: Influence of Aerobic Exercise Training. DuBose LE, Weng TB, Pierce GL, Wharff C, Reist L, Hamilton C, O'Deen A, Dubishar KM, Lane-Cordova AD, Voss MW. J Appl Physiol (1985). 2022 Apr 28. doi: 10.1152/japplphysiol.00599.2021. PMID: 35482329
Limb-Girdle Muscular Dystrophy R9 due to a Novel Complex Insertion/Duplication Variant in FKRP Gene. Willis E, Moore SA, Cox MO, Stefans V, Aravindhan A, Gokden M, Veerapandiyan A. Child Neurol Open. 2022 Apr 28;9:2329048X221097518. doi: 10.1177/2329048X221097518. PMID: 35557983
Neutrophil dysfunction in the pathogenesis of cystic fibrosis. Wang G, Nauseef WM. Blood. 2022 Apr 28;139(17):2622-2631. doi: 10.1182/blood.2021014699. PMID: 35213685

Apr 27

Melanocortin MC4R receptor is required for energy expenditure but not blood pressure effects of angiotensin II within the mouse brain. Oliveira V, Riedl RA, Claflin KE, Marin Mathieu N, Ritter ML, Balapattabi K, Wackman KK, Reho JJ, Brozoski DT, Morgan DA, Cui H, Rahmouni K, Burnett CML, Nakagawa P, Sigmund CD, Morselli LL, Grobe JL. Physiol Genomics. 2022 Apr 27. doi: 10.1152/physiolgenomics.00015.2022. PMID: 35476598
Pathogen Stimulation of Interleukin-8 from Human Vaginal Epithelial Cells through CD40. Schlievert PM, Kilgore SH, Benavides A, Klingelhutz AJ. Microbiol Spectr. 2022 Apr 27;10(2):e0010622. doi: 10.1128/spectrum.00106-22. PMID: 35297656
RBD-mRNA vaccine induces broadly neutralizing antibodies against Omicron and multiple other variants and protects mice from SARS-CoV-2 challenge. Shi J, Zheng J, Zhang X, Tai W, Odle AE, Perlman S, Du L. Transl Res. 2022 Apr 27:S1931-5244(22)00093-7. doi: 10.1016/j.trsl.2022.04.007. PMID: 35489692

April 26

Diet-Driven Inflammation and Insulinemia and Risk of Interval Breast Cancer. Zhang Z, Tabung FK, Jin Q, Curran G, Irvin VL, Shannon J, Velie EM, Manson JE, Simon MS, Vitolins M, Valencia CI, Snetselaar L, Jindal S, Schedin P. Nutr Cancer. 2022 Apr 26:1-15. doi: 10.1080/01635581.2022.2063350. PMID: 35471124
Quantitative CT Characteristics of Cluster Phenotypes in the Severe Asthma Research Program Cohorts. Trivedi AP, Hall C, Goss CW, Lew D, Krings JG, McGregor MC, Samant M, Sieren JP, Li H, Schechtman KB, Schirm J, McEleney S, Peterson S, Moore WC, Bleecker ER, Meyers DA, Israel E, Washko GR, Levy BD, Leader JK, Wenzel SE, Fahy JV, Schiebler ML, Fain SB, Jarjour NN, Mauger DT, Reinhardt JM, Newell JD Jr, Hoffman EA, Castro M, Sheshadri A; NHLBI Severe Asthma Research Program (SARP). Radiology. 2022 Apr 26:210363. doi: 10.1148/radiol.210363. PMID: 35471111

April 25

CGRP Administration Into the Cerebellum Evokes Light Aversion, Tactile Hypersensitivity, and Nociceptive Squint in Mice. Wang M, Duong TL, Rea BJ, Waite JS, Huebner MW, Flinn HC, Russo AF, Sowers LP. Front Pain Res (Lausanne). 2022 Apr 25;3:861598. doi: 10.3389/fpain.2022.861598. PMID: 35547239
Differential Functions of Individual Transcription Factor Binding Sites in the Tandem Repeats Found in Clinically Relevant cyp51A Promoters in Aspergillus fumigatus. Paul S, Verweij PE, Melchers WJG, Moye-Rowley WS. mBio. 2022 Apr 25:e0070222. doi: 10.1128/mbio.00702-22. PMID: 35467427
Multi-Site Observational Study to Assess Biomarkers for Susceptibility or Resilience to Chronic Pain: The Acute to Chronic Pain Signatures (A2CPS) Study Protocol. Berardi G, Frey-Law L, Sluka KA, Bayman EO, Coffey CS, Ecklund D, Vance CGT, Dailey DL, Burns J, Buvanendran A, McCarthy RJ, Jacobs J, Zhou XJ, Wixson R, Balach T, Brummett CM, Clauw D, Colquhoun D, Harte SE, Harris RE, Williams DA, Chang AC, Waljee J, Fisch KM, Jepsen K, Laurent LC, Olivier M, Langefeld CD, Howard TD, Fiehn O, Jacobs JM, Dakup P, Qian WJ, Swensen AC, Lokshin A, Lindquist M, Caffo BS, Crainiceanu C, Zeger S, Kahn A, Wager T, Taub M, Ford J, Sutherland SP, Wandner LD. Front Med (Lausanne). 2022 Apr 25;9:849214. doi: 10.3389/fmed.2022.849214. PMID: 35547202

April 24

Rural and urban differences in perceptions, behaviors, and health care disruptions during the COVID-19 pandemic. Greteman BB, Garcia-Auguste CJ, Gryzlak BM, Kahl AR, Lutgendorf SK, Chrischilles EA, Charlton ME. J Rural Health. 2022 Apr 24. doi: 10.1111/jrh.12667. PMID: 35466479

April 23

Frequency and Duration of, and Risk Factors for, Diagnostic Delays Associated with Histoplasmosis. Miller AC, Arakkal AT, Koeneman SH, Cavanaugh JE, Thompson GR, Baddley JW, Polgreen PM. J Fungi (Basel). 2022 Apr 23;8(5):438. doi: 10.3390/jof8050438. PMID: 35628693

April 20

Exploring unintended consequences of adult antimicrobial stewardship programs: An Emerging Infections Network survey. Durkin MJ, Lake J, Polgreen PM, Beekmann SE, Hersh AL, Newland JG. Infect Control Hosp Epidemiol. 2022 Apr 20:1-3. doi: 10.1017/ice.2022.104. PMID: 35441586
Pharmacological ascorbate improves the response to platinum-based chemotherapy in advanced stage non-small cell lung cancer. Furqan M, Abu-Hejleh T, Stephens LM, Hartwig SM, Mott SL, Pulliam CF, Petronek M, Henrich JB, Fath MA, Houtman JC, Varga SM, Bodeker KL, Bossler AD, Bellizzi AM, Zhang J, Monga V, Mani H, Ivanovic M, Smith BJ, Byrne MM, Zeitler W, Wagner BA, Buettner GR, Cullen JJ, Buatti JM, Spitz DR, Allen BG. Redox Biol. 2022 Apr 20;53:102318. doi: 10.1016/j.redox.2022.102318. PMID: 35525024

April 19

Inter-domain communication in SARS-CoV-2 spike proteins controls protease-triggered cell entry. Qing E, Li P, Cooper L, Schulz S, Jäck HM, Rong L, Perlman S, Gallagher T. Cell Rep. 2022 Apr 19:110786. doi: 10.1016/j.celrep.2022.110786. PMID: 35477024

April 18

D-Cysteine ethylester and D-cystine dimethylester reverse the deleterious effects of morphine on arterial blood-gas chemistry and Alveolar-arterial gradient in anesthetized rats. Getsy PM, Young AP, Grossfield A, Seckler JM, Wilson CG, Gaston B, Bates JN, Lewis SJ. Respir Physiol Neurobiol. 2022 Apr 18:103912. doi: 10.1016/j.resp.2022.103912. PMID: 35447347
Neurofilament Light Protein as a Potential Blood Biomarker for Huntington's Disease in Children. Byrne LM, Schultz JL, Rodrigues FB, van der Plas E, Langbehn D, Nopoulos PC, Wild EJ. Mov Disord. 2022 Apr 18. doi: 10.1002/mds.29027. PMID: 35437792

April 16

Gallbladder Disease and Risk of Type 2 Diabetes in Postmenopausal Women: A Women's Health Initiative Study. Ako AA, Michael YL, Robinson LF, Wactawski-Wende J, Shadyab AH, Garcia L, Nriagu BN, Saquib N, Nassir R, Liu S, Wallace RB. Am J Epidemiol. 2022 Apr 16:kwac074. doi: 10.1093/aje/kwac074. PMID: 35434732

April 15

Ferret Lung Transplantation Models Differential Lymphoid Aggregate Morphology Between Restrictive and Obstructive Forms of Chronic Lung Allograft Dysfunction. Lynch TJ, Ahlers BA, Swatek AM, Ievlev V, Pai AC, Brooks L, Tang Y, Evans IA, Meyerholz DK, Engelhardt JF, Parekh KR. Transplantation. 2022 Apr 15. doi: 10.1097/TP.0000000000004148. PMID: 35442232
Virus-Specific Regulatory T Cells Persist as Memory in a Neurotropic Coronavirus Infection. Sariol A, Zhao J, Abrahante JE, Perlman S. J Immunol. 2022 Apr 15;208(8):1989-1997. doi: 10.4049/jimmunol.2100794. PMID: 35365567

April 14

Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT3102. Brashears CB, Prudner BC, Rathore R, Caldwell KE, Dehner CA, Buchanan JL, Lange SES, Poulin N, Sehn JK, Roszik J, Spitzer D, Jones KB, O'Keefe RJ, Nielsen TO, Taylor EB, Held JM, Hawkins W, Van Tine BA. Clin Cancer Res. 2022 Apr 14:clincanres.0470.2022. doi: 10.1158/1078-0432.CCR-22-0470. PMID: 35421237

April 11

Myeloid Cell PKM2 Deletion Enhances Efferocytosis and Reduces Atherosclerosis. Doddapattar P, Dev R, Ghatge M, Patel RB, Jain M, Dhanesha N, Lentz SR, Chauhan AK. Circ Res. 2022 Apr 11:101161CIRCRESAHA121320704. doi: 10.1161/CIRCRESAHA.121.320704. PMID: 35400205

April 6

A Genotype-Phenotype Analysis of Glutathione Peroxidase 4 in Human Atrial Myocardium and Its Association with Postoperative Atrial Fibrillation. Berdaweel IA, Hart AA, Jatis AJ, Karlan N, Akhter SA, Gaine ME, Smith RM, Anderson EJ. Antioxidants (Basel). 2022 Apr 6;11(4):721. doi: 10.3390/antiox11040721. PMID: 35453406

April 9

Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo. Kohlmeyer JL, Kaemmer CA, Lingo JJ, Voigt E, Leidinger MR, McGivney GR, Scherer A, Koppenhafer SL, Gordon DJ, Breheny P, Meyerholz DK, Tanas MR, Dodd RD, Quelle DE. Neurooncol Adv. 2022 Apr 9;4(1):vdac047. doi: 10.1093/noajnl/vdac047. PMID: 35571990

April 7

Familial Glaucoma-A Pedigree Revisited With Genetic Testing After 70 Years. Quigley HA, Stone EM, Fingert JH. JAMA Ophthalmol. 2022 Apr 7. doi: 10.1001/jamaophthalmol.2022.0556. PMID: 35389460

April 4

Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events. Jacobs DR Jr, Woo JG, Sinaiko AR, Daniels SR, Ikonen J, Juonala M, Kartiosuo N, Lehtimäki T, Magnussen CG, Viikari JSA, Zhang N, Bazzano LA, Burns TL, Prineas RJ, Steinberger J, Urbina EM, Venn AJ, Raitakari OT, Dwyer T. N Engl J Med. 2022 Apr 4. doi: 10.1056/NEJMoa2109191. PMID: 35373933

April 1

May 2022

May 30

Association of multiple sclerosis with risk of mortality among a nationally representative sample of adults in the United States. Titcomb TJ, Bao W, Du Y, Liu B, Snetselaar LG, Wahls TL. Mult Scler J Exp Transl Clin. 2022 May 30;8(2):20552173221104009. doi: 10.1177/20552173221104009. PMID: 35665135

May 27

Large1 gene transfer in older myd mice with severe muscular dystrophy restores muscle function and greatly improves survival. Yonekawa T, Rauckhorst AJ, El-Hattab S, Cuellar MA, Venzke D, Anderson ME, Okuma H, Pewa AD, Taylor EB, Campbell KP. Sci Adv. 2022 May 27;8(21):eabn0379. doi: 10.1126/sciadv.abn0379. PMID: 35613260
Sox9 and Lef1 regulate the fate and behavior of airway glandular progenitors in response to injury. Ievlev V, Jensen-Cody C, Lynch TJ, Pai AC, Park S, Shahin W, Wang K, Parekh KR, Engelhardt JF. Stem Cells. 2022 May 27:sxac038. doi: 10.1093/stmcls/sxac038. PMID: 35639980

May 26

Dietary inorganic nitrate/nitrite supplementation reduces central and peripheral blood pressure in patients with type 2 diabetes mellitus. Bock JM, Hughes WE, Ueda K, Feider AJ, Hanada S, Casey DP. Am J Hypertens. 2022 May 26:hpac068. doi: 10.1093/ajh/hpac068. PMID: 35639721
S-Nitroso-L-Cysteine Stereoselectively Blunts the Deleterious Effects of Fentanyl on Breathing While Augmenting Antinociception in Freely-Moving Rats. Getsy PM, Baby SM, Gruber RB, Gaston B, Lewis THJ, Grossfield A, Seckler JM, Hsieh YH, Bates JN, Lewis SJ. Front Pharmacol. 2022 May 26;13:892307. doi: 10.3389/fphar.2022.892307. PMID: 3572120

May 24

Anion Transport Across Human Gallbladder Organoids and Monolayers. Zarei K, Thornell IM, Stoltz DA. Front Physiol. 2022 May 24;13:882525. doi: 10.3389/fphys.2022.882525. PMID: 35685290
Component Analysis of Nucleolar Protein Compartments using Xenopus laevis oocytes. Lavering ED, Petros IN, Weeks DL. Dev Growth Differ. 2022 May 24. doi: 10.1111/dgd.12794. PMID: 35607824
The Effect of Progressive Lateral Column Lengthening in a Novel Stage II-B Flatfoot Cadaveric Model Evaluated Using Software-Guided Radiographic Measurements of Foot Alignment. Femino JE, Kern A, Schumer R, Anthony C, Kruse AJ, Goetz J. Foot Ankle Int. 2022 May 24:10711007221091817. doi: 10.1177/10711007221091817. PMID: 35611474
MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells. Comar CE, Otter CJ, Pfannenstiel J, Doerger E, Renner DM, Tan LH, Perlman S, Cohen NA, Fehr AR, Weiss SR. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2123208119. doi: 10.1073/pnas.2123208119. PMID: 35594398

May 23

Behavioral features in child and adolescent huntingtin gene-mutation carriers. Reasoner EE, van der Plas E, Al-Kaylani HM, Langbehn DR, Conrad AL, Schultz JL, Epping EA, Magnotta VA, Nopoulos PC. Brain Behav. 2022 May 23:e2630. doi: 10.1002/brb3.2630. PMID: 35604958

May 20

Cytokine receptor gp130 promotes postnatal proliferation of cardiomyocytes required for the normal functional development of the heart. Kawagishi H, Nakada T, Numaga-Tomita T, Larrañaga M, Guo A, Song LS, Yamada M. Am J Physiol Heart Circ Physiol. 2022 May 20. doi: 10.1152/ajpheart.00698.2021. PMID: 35594067
MRAP2 inhibits β-arrestin recruitment to the ghrelin receptor by preventing GHSR1a phosphorylation. Rouault AAJ, Buscaglia P, Sebag JA. J Biol Chem. 2022 May 20:102057. doi: 10.1016/j.jbc.2022.102057. PMID: 35605660

May 19

Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events. Jacobs DR Jr, Woo JG, Sinaiko AR, Daniels SR, Ikonen J, Juonala M, Kartiosuo N, Lehtimäki T, Magnussen CG, Viikari JSA, Zhang N, Bazzano LA, Burns TL, Prineas RJ, Steinberger J, Urbina EM, Venn AJ, Raitakari OT, Dwyer T. N Engl J Med. 2022 May 19;386(20):1877-1888. doi: 10.1056/NEJMoa2109191. PMID: 35373933
Effective Interferon Lambda Treatment Regimen To Control Lethal MERS-CoV Infection in Mice. Dijkman R, Verma AK, Selvaraj M, Ghimire R, Gad HH, Hartmann R, More S, Perlman S, Thiel V, Channappanavar R. J Virol. 2022 May 19:e0036422. doi: 10.1128/jvi.00364-22. PMID: 35588276
Redox Mechanisms of Platelet Activation in Aging. Gu SX, Dayal S. Antioxidants (Basel). 2022 May 19;11(5):995. doi: 10.3390/antiox11050995. PMID: 35624860

May 18

Associations of coffee/caffeine consumption with postmenopausal breast cancer risk and their interactions with postmenopausal hormone use. Yaghjyan L, McLaughlin E, Lehman A, Neuhouser ML, Rohan T, Lane DS, Snetselaar L, Paskett E. Eur J Nutr. 2022 May 18. doi: 10.1007/s00394-022-02899-8. PMID: 35583696
Oxidation of ferumoxytol by ionizing radiation releases iron. An electron paramagnetic resonance study. Petronek MS, Spitz DR, Buettner GR, Allen BG. J Radiat Res. 2022 May 18;63(3):378-384. doi: 10.1093/jrr/rrac008. PMID: 35301531

May 15

Favorable Outcomes with Early Component Separation, Primary Closure of Necrotizing Soft Tissue Infections of the Genitalia (Fournier's Gangrene) Debridement Wound Defects. Sandberg JM, Warner HL, Flynn KJ, Sexton SM, Pham HT, Kandler BW, Polgreen PM, Erickson BA. Urology. 2022 May 15:S0090-4295(22)00366-1. doi: 10.1016/j.urology.2022.03.042. PMID: 35584736

May 14

Posterior Fossa Sub-Arachnoid Cysts Observed in Patients with Bipolar Disorder: a Retrospective Cohort Study. Ewald VAM, Purnell JR, Bruss JE, Barsotti EJ, Aldine AS, Mahachi KG, Wemmie JA, Magnotta VA, Boes AD, Parker KL, Fiedorowicz JG. Cerebellum. 2022 May 14. doi: 10.1007/s12311-022-01408-1. PMID: 35568792

May 13

COVID-19 breakthrough infections in rheumatic diseases patients after vaccination. Alshukairi AN, Al-Omari A, Albeity A, Alandijany TA, Hassan AM, El-Kafrawy SA, Dada A, Al Hroub MK, El-Saed A, Bissar LS, Daghmush RM, Al-Ghamdi SMG, Perlman S, Azhar EI, Halabi H. J Infect Public Health. 2022 May 13;15(6):685-688. doi: 10.1016/j.jiph.2022.05.005. PMID: 35623243

May 12

Body-mass index trajectories from childhood to mid-adulthood and their sociodemographic predictors: Evidence from the International Childhood Cardiovascular Cohort (i3C) Consortium. Cleland V, Tian J, Buscot MJ, Magnussen CG, Bazzano L, Burns TL, Daniels S, Dwyer T, Hutri-Kahonen N, Ikonen J, Jacobs D, Juonala M, Prineas R, Raitakari O, Sinaiko A, Steinberger J, Urbina EM, Woo JG, Venn A. EClinicalMedicine. 2022 May 12;48:101440. doi: 10.1016/j.eclinm.2022.101440. PMID: 35706485
Long-term follow-up of smokers following lung and colorectal cancer diagnosis. Park ER, Skurla SE, Caballero GYJ, Friedman ER, Ponzani C, Wallace R, Malin J, Keating NL. Support Care Cancer. 2022 May 12. doi: 10.1007/s00520-022-07111-5. PMID: 35552828

May 10

An open source and convenient method for the wide-spread testing of COVID-19 using deep throat sputum samples. Huang SC, Pak TK, Graber CP, Searby CC, Liu G, Marcy J, Yaszemski AK, Bedell K, Bui E, Perlman S, Zhang Q, Wang K, Sheffield VC, Carter CS. PeerJ. 2022 May 10;10:e13277. doi: 10.7717/peerj.13277. PMID: 35573180
CGRP and the Calcitonin Receptor are Co-Expressed in Mouse, Rat and Human Trigeminal Ganglia Neurons. Rees TA, Russo AF, O'Carroll SJ, Hay DL, Walker CS. Front Physiol. 2022 May 10;13:860037. doi: 10.3389/fphys.2022.860037. eCollection 2022. PMID: 35620595
Postpartum ambulatory and home blood pressure monitoring in women with history of preeclampsia: Diagnostic agreement and detection of masked hypertension. Nuckols VR, Stroud AK, Armstrong MK, Brandt DS, Santillan MK, Santillan DA, Pierce GL. Pregnancy Hypertens. 2022 May 10;29:23-29. doi: 10.1016/j.preghy.2022.05.003. PMID: 35671544

May 6

Tany-Seq: Integrated Analysis of the Mouse Tanycyte Transcriptome. Sullivan AI, Potthoff MJ, Flippo KH. Cells. 2022 May 6;11(9):1565. doi: 10.3390/cells11091565. PMID: 35563871

May 5

Racial/Ethnic Disparities in Alzheimer's Disease Risk: Role of Exposure to Ambient Fine Particles. Younan D, Wang X, Gruenewald T, Gatz M, Serre ML, Vizuete W, Braskie MN, Woods NF, Kahe K, Garcia L, Lurmann F, Manson JE, Chui HC, Wallace RB, Espeland MA, Chen JC. J Gerontol A Biol Sci Med Sci. 2022 May 5;77(5):977-985. doi: 10.1093/gerona/glab231. PMID: 34383042

May 4

Blood Pressure Variability and Heart Failure Hospitalization: Results From the Women's Health Initiative. Haring B, Hunt RP, Manson JE, LaMonte MJ, Klein L, Allison MA, Wild RA, Wallace RB, Shadyab AH, Breathett K, Eaton C, Wassertheil-Smoller S, Shimbo D. Am J Prev Med. 2022 May 4:S0749-3797(22)00159-3. doi: 10.1016/j.amepre.2022.03.007. PMID: 35525685
Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis. Li Y, Talbot CL, Chandravanshi B, Ksiazek A, Sood A, Chowdhury KH, Maschek JA, Cox J, Babu AKS, Paz HA, Babu PVA, Meyerholz DK, Wankhade UD, Holland W, Shyong Tai E, Summers SA, Chaurasia B. Sci Rep. 2022 May 4;12(1):7273. doi:10.1038/s41598-022-11219-3. PMID: 35508667
Pathways Linking Nicotinamide Adenine Dinucleotide Phosphate Production to Endoplasmic Reticulum Protein Oxidation and Stress. Gansemer ER, Rutkowski DT. Front Mol Biosci. 2022 May 4;9:858142. doi: 10.3389/fmolb.2022.858142. eCollection 2022. PMID: 35601828. Review

May 3

Inter-domain communication in SARS-CoV-2 spike proteins controls protease-triggered cell entry. Qing E, Li P, Cooper L, Schulz S, Jäck HM, Rong L, Perlman S, Gallagher T. Cell Rep. 2022 May 3;39(5):110786. doi: 10.1016/j.celrep.2022.110786. PMID: 35477024

May 2

Alveolar macrophages protect mice from MERS-CoV-induced pneumonia and severe disease. Channappanavar R, Selvaraj M, More S, Perlman S. Vet Pathol. 2022 May 2:3009858221095270. doi: 10.1177/03009858221095270. PMID: 35499307
PCB Sulfates in Serum from Mothers and Children in Urban and Rural U.S. Communities. Zhang D, Saktrakulkla P, Marek RF, Lehmler HJ, Wang K, Thorne PS, Hornbuckle KC, Duffel MW. Environ Sci Technol. 2022 May 2. doi: 10.1021/acs.est.2c00223. PMID: 35500099

May 1

June 2022

June 29

Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Antioxidants (Basel). 2022 Jun 29;11(7):1297. doi: 10.3390/antiox11071297. PMID: 35883787
Delivery of therapeutic carbon monoxide by gas-entrapping materials. Byrne JD, Gallo D, Boyce H, Becker SL, Kezar KM, Cotoia AT, Feig VR, Lopes A, Csizmadia E, Longhi MS, Lee JS, Kim H, Wentworth AJ, Shankar S, Lee GR, Bi J, Witt E, Ishida K, Hayward A, Kuosmanen JLP, Jenkins J, Wainer J, Aragon A, Wong K, Steiger C, Jeck WR, Bosch DE, Coleman MC, Spitz DR, Tift M, Langer R, Otterbein LE, Traverso G. Sci Transl Med. 2022 Jun 29;14(651):eabl4135. doi: 10.1126/scitranslmed.abl4135. PMID: 35767653
Sex-Specific Differences in Endothelial Function Are Driven by Divergent Mitochondrial Ca²⁺ Handling. Damacena de Angelis C, Endoni BT, Nuno D, Lamping K, Ledolter J, Koval OM, Grumbach IM. J Am Heart Assoc. 2022 Jun 29:e023912. doi: 10.1161/JAHA.121.023912. PMID: 35766269

June 28

Differential Functions of Individual Transcription Factor Binding Sites in the Tandem Repeats Found in Clinically Relevant cyp51A Promoters in Aspergillus fumigatus. Paul S, Verweij PE, Melchers WJG, Moye-Rowley WS. mBio. 2022 Jun 28;13(3):e0070222. doi: 10.1128/mbio.00702-22. PMID: 35467427
Quantification of lung ventilation defects on hyperpolarized MRI: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD study. Zhang X, Angelini ED, Haghpanah FS, Laine AF, Sun Y, Hiura GT, Dashnaw SM, Prince MR, Hoffman EA, Ambale-Venkatesh B, Lima JA, Wild JM, Hughes EW, Barr RG, Shen W. Magn Reson Imaging. 2022 Jun 28;92:140-149. doi: 10.1016/j.mri.2022.06.016. PMID: 35777684
Reduced blood flow by laser speckle flowgraphy after ¹²⁵I-plaque brachytherapy for uveal melanoma. Tamplin MR, Wang JK, Vitale AH, Hashimoto R, Garvin MK, Binkley EM, Hyer DE, Buatti JM, Boldt HC, Kardon RH, Grumbach IM. BMC Ophthalmol. 2022 Jun 28;22(1):285. doi: 10.1186/s12886-022-02505-9. PMID: 35765019

June 25

Utility of CD138/syndecan-1 immunohistochemistry for localization of plasmacytes is tissue-dependent in B6 mice. Meyerholz DK, Leidinger MR, Goeken JA, Businga TR, Akers A, Vizuett S, Kaemmer CA, Kohlmeyer JL, Dodd RD, Quelle DE. BMC Res Notes. 2022 Jun 25;15(1):219. doi: 10.1186/s13104-022-06100-5. PMID: 35752869

June 24

Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function. Sheikh MO, Capicciotti CJ, Liu L, Praissman J, Ding D, Mead DG, Brindley MA, Willer T, Campbell KP, Moremen KW, Wells L, Boons GJ. Nat Commun. 2022 Jun 24;13(1):3617. doi: 10.1038/s41467-022-31205-7. PMID: 35750689
Management of Histoplasmosis by Infectious Disease Physicians. Mazi PB, Arnold SR, Baddley JW, Bahr NC, Beekmann SE, McCarty TP, Polgreen PM, Rauseo AM, Spec A. Open Forum Infect Dis. 2022 Jun 24;9(7):ofac313. doi: 10.1093/ofid/ofac313. PMID: 35899286
Psychotropic medication use and Parkinson's disease risk amongst older women. Beydoun HA, Saquib N, Wallace RB, Chen JC, Coday M, Naughton MJ, Beydoun MA, Shadyab AH, Zonderman AB, Brunner RL. Ann Clin Transl Neurol. 2022 Jun 24. doi: 10.1002/acn3.51614. PMID: 35748105

June 23

D-Cysteine Ethyl Ester Reverses the Deleterious Effects of Morphine on Breathing and Arterial Blood-Gas Chemistry in Freely-Moving Rats. Getsy PM, Baby SM, May WJ, Young AP, Gaston B, Hodges MR, Forster HV, Bates JN, Wilson CG, Lewis THJ, Hsieh YH, Lewis SJ. Front Pharmacol. 2022 Jun 23;13:883329. doi: 10.3389/fphar.2022.883329. PMID: 35814208
Stimulation of CGRP-expressing neurons in the medial cerebellar nucleus induces light and touch sensitivity in mice. Wang M, Castonguay WC, Duong TL, Huebner MW, Flinn HC, Greenway AM, Russo AF, Sowers LP. Neurobiol Pain. 2022 Jun 23;12:100098. doi: 10.1016/j.ynpai.2022.100098. PMID: 35782531

June 22

A Task-Specific Algorithm to Estimate Occupational (1→3)-β-D-glucan Exposure for Farmers in the Biomarkers of Exposure and Effect in Agriculture Study. Friesen MC, Hung F, Xie S, Viet SM, Deziel NC, Locke SJ, Josse PR, Sauvé JF, Andreotti G, Thorne PS, Beane-Freeman LE, Hofmann JN. Ann Work Expo Health. 2022 Jun 22:wxac041. doi: 10.1093/annweh/wxac041. PMID: 35731645
Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice. McLendon JM, Zhang X, Matasic DS, Kumar M, Koval OM, Grumbach IM, Sadayappan S, London B, Boudreau RL. J Am Heart Assoc. 2022 Jun 22:e025687. doi: 10.1161/JAHA.122.025687. PMID: 35730644
Voluntary Exercise Eliminates Maternal Gestational Hypertension-Induced Hypertensive Response Sensitization to Postweaning High-Fat Diet in Male Adult Offspring. Xue B, Yu Y, Beltz TG, Guo F, Wei SG, Kim Johnson A. Hypertension. 2022 Jun 22:101161HYPERTENSIONAHA12219608. doi: 10.1161/HYPERTENSIONAHA.122.19608. PMID: 35730432

June 21

Inappropriate Sinus Tachycardia: Etiology, Pathophysiology, and Management: JACC Review Topic of the Week. Ahmed A, Pothineni NVK, Charate R, Garg J, Elbey M, de Asmundis C, LaMeir M, Romeya A, Shivamurthy P, Olshansky B, Russo A, Gopinathannair R, Lakkireddy D. J Am Coll Cardiol. 2022 Jun 21;79(24):2450-2462. doi: 10.1016/j.jacc.2022.04.019. PMID: 35710196. Review.

June 17

Extracellular biomolecular free radical formation during injury. Hines MR, Goetz JE, Gomez-Contreras PC, Rodman SN 3rd, Liman S, Femino EL, Kluz PN, Wagner BA, Buettner GR, Kelley EE, Coleman MC. Free Radic Biol Med. 2022 Jun 17:S0891-5849(22)00450-6. doi: 10.1016/j.freeradbiomed.2022.06.223. PMID: 35724853
L-NAC reverses of the adverse effects of fentanyl infusion on ventilation and blood-gas chemistry. Getsy PM, Baby SM, May WJ, Lewis THJ, Bates JN, Hsieh YH, Gaston B, Lewis SJ. Biomed Pharmacother. 2022 Jun 17;153:113277. doi: 10.1016/j.biopha.2022.113277. PMID: 35724513
Outcomes of In-Hospital Cardiac Arrest Among Hospitals With and Without Telemedicine Critical Care. Ofoma UR, Drewry AM, Maddox TM, Boyle W, Deych E, Kollef M, Girotra S, Joynt Maddox KE; American Heart Association's Get With The Guidelines®- Resuscitation Investigators. Resuscitation. 2022 Jun 17:S0300-9572(22)00570-6. doi: 10.1016/j.resuscitation.2022.06.008. PMID: 35724851

June 16

Mice expressing P301S mutant human tau have deficits in interval timing. Larson T, Khandelwal V, Weber MA, Leidinger MR, Meyerholz DK, Narayanan NS, Zhang Q. Behav Brain Res. 2022 Jun 16:113967. doi: 10.1016/j.bbr.2022.113967. PMID: 35718229

June 15

Effectiveness and acceptability of intranasal povidone-iodine decolonization among fracture fixation surgery patients to reduce Staphylococcus aureus nasal colonization. Schweizer ML, Herwaldt LA, Boyken L, Pottinger J, Quinn R, Diekema DJ, Armstrong-Pavlik F, Ward M, Sekar P, Willey MC. Infect Control Hosp Epidemiol. 2022 Jun 15:1-3. doi: 10.1017/ice.2022.134. PMID: 35701860

June 13

Time course of pulmonary inflammation and trace element biodistribution during and after sub-acute inhalation exposure to copper oxide nanoparticles in a murine model. Areecheewakul S, Adamcakova-Dodd A, Haque E, Jing X, Meyerholz DK, O'Shaughnessy PT, Thorne PS, Salem AK. Part Fibre Toxicol. 2022 Jun 13;19(1):40. doi: 10.1186/s12989-022-00480-z. PMID: 35698146

June 10

Challenges and Inclusive Practices for LGBTQIA2S+ Scientists in the American Physiological Society. Moreira JD, Bates ML, Roepke TA. Am J Physiol Heart Circ Physiol. 2022 Jun 10. doi: 10.1152/ajpheart.00234.2022. PMID: 35687502
rAAV-MEDIATED EDITING OF THE G551D CFTR MUTATION IN FERRET AIRWAY BASAL CELLS. Yan Z, Vorhies K, Feng Z, Park SY, Choi SH, Zhang Y, Winter M, Sun X, Engelhardt JF. Hum Gene Ther. 2022 Jun 10. doi: 10.1089/hum.2022.036. PMID: 35686451

June 9

Serum antioxidant vitamins and respiratory morbidity and mortality: a pooled analysis. Salo PM, Mendy A, Wilkerson J, Molsberry SA, Feinstein L, London SJ, Fessler MB, Thorne PS, Zeldin DC. Respir Res. 2022 Jun 9;23(1):150. doi: 10.1186/s12931-022-02059-w. PMID: 35681205
Upper and Lower Airway Dysanapsis and Airflow Obstruction Among Older Adults. Smith BM, Wiemken A, Hoffman EA, Keenan BT, Allen NB, Bertoni AG, Jacobs DR Jr, Michos ED, Watson KE, Redline S, Schwab RJ, Barr RG, Heckbert SR. Am J Respir Crit Care Med. 2022 Jun 9. doi: 10.1164/rccm.202202-0353LE. PMID: 35679318

June 8

Effective Interferon Lambda Treatment Regimen To Control Lethal MERS-CoV Infection in Mice. Dijkman R, Verma AK, Selvaraj M, Ghimire R, Gad HH, Hartmann R, More S, Perlman S, Thiel V, Channappanavar R. J Virol. 2022 Jun 8;96(11):e0036422. doi: 10.1128/jvi.00364-22. PMID: 35588276

June 6

Engineering viral genomics and nano-liposomes in microfluidic platforms for patient-specific analysis of SARS-CoV-2 variants. Satta S, Shahabipour F, Gao W, Lentz SR, Perlman S, Ashammakhi N, Hsiai T. Theranostics. 2022 Jun 6;12(10):4779-4790. doi: 10.7150/thno.72339. eCollection 2022. PMID: 35832078. Review.
Vitamin D-mediated effects on airway innate immunity in vitro. Stapleton EM, Keck K, Windisch R, Stroik MR, Thurman AL, Zabner J, Thornell IM, Pezzulo AA, Klesney-Tait J, Comellas AP. PLoS One. 2022 Jun 6;17(6):e0269647. doi: 10.1371/journal.pone.0269647. eCollection 2022. PMID: 35666753

June 4

NMR resonance assignments of the DNA binding domain of mouse Junctophilin-2. Yu L, Hall DD, Zhao W, Song LS. Biomol NMR Assign. 2022 Jun 4. doi: 10.1007/s12104-022-10091-6. PMID: 35665900

June 3

TP53 Sequencing and p53 Immunohistochemistry Predict Outcomes When Bevacizumab Is Added to Frontline Chemotherapy in Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study. Thiel KW, Devor EJ, Filiaci VL, Mutch D, Moxley K, Alvarez Secord A, Tewari KS, McDonald ME, Mathews C, Cosgrove C, Dewdney S, Aghajanian C, Samuelson MI, Lankes HA, Soslow RA, Leslie KK. J Clin Oncol. 2022 Jun 3:JCO2102506. doi: 10.1200/JCO.21.02506. PMID: 35658479

June 2

Coronavirus Disease-2019 (COVID-19) among Non-physician Healthcare Personnel by Work Location at a Tertiary Care Center, Iowa, 2020-2021. Kobayashi T, Heinemann J, Trannel A, Marra AR, Alsuhaibani M, Etienne W, Sheeler LL, Abosi O, Holley S, Kukla MB, Dains A, Jenn KE, Meacham H, Hanna B, Ford B, Brust K, Wellington M, Hartley PG, Diekema DJ, Salinas JL. Infect Control Hosp Epidemiol. 2022 Jun 2:1-11. doi: 10.1017/ice.2022.148. PMID: 35652600

June 1

July 2022

July 28

A Computed Tomography Imaging-based Subject-Specific Whole-Lung Deposition Model. Zhang X, Li F, Rajaraman PK, Choi J, Comellas AP, Hoffman EA, Smith BM, Lin CL. Eur J Pharm Sci. 2022 Jul 28:106272. doi: 10.1016/j.ejps.2022.106272. PMID: 35908637
Mitochondrial Ca²⁺ Uptake Drives Endothelial Injury By Radiation Therapy. Ait-Aissa K, Koval OM, Lindsey NR, Grumbach IM. Arterioscler Thromb Vasc Biol. 2022 Jul 28:101161ATVBAHA122317869. doi: 10.1161/ATVBAHA.122.317869. PMID: 35899616

July 26

College students report less physical activity and more sedentary behavior during the COVID-19 pandemic. Dziewior J, Carr LJ, Pierce GL, Whitaker K. J Am Coll Health. 2022 Jul 26:1-9. doi: 10.1080/07448481.2022.2100708. PMID: 35881778

July 25

Disruption of dopamine receptor 1 localization to primary cilia impairs signaling in striatal neurons. Stubbs T, Koemeter-Cox A, Bingman JI, Zhao F, Kalyanasundaram A, Rowland LA, Periasamy M, Carter CS, Sheffield VC, Askwith CC, Mykytyn K. J Neurosci. 2022 Jul 25:JN-RM-0497-22. doi: 10.1523/JNEUROSCI.0497-22.2022. PMID: 35882560

July 23

Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501Y_MA30 Strain of SARS-CoV-2. Kibler KV, Szczerba M, Lake D, Roeder AJ, Rahman M, Hogue BG, Roy Wong LY, Perlman S, Li Y, Jacobs BL. Vaccines (Basel). 2022 Jul 23;10(8):1172. doi: 10.3390/vaccines10081172. PMID: 35893821

July 21

Choroidal endothelial and macrophage gene expression in atrophic and neovascular macular degeneration. Voigt AP, Mullin NK, Mulfaul K, Lozano LP, Wiley LA, Flamme-Wiese MJ, Boese EA, Han IC, Scheetz TE, Stone EM, Tucker BA, Mullins RF. Hum Mol Genet. 2022 Jul 21;31(14):2406-2423. doi: 10.1093/hmg/ddac043. PMID: 35181781

July 19

Editorial: Calcitonin Gene-Related Peptide: Novel Biology and Treatments. Brain SD, Russo AF, Hay DL. Front Physiol. 2022 Jul 19;13:964568. doi: 10.3389/fphys.2022.964568. PMID: 35928563

July 18

WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia. Rehman T, Karp PH, Thurman AL, Mather SE, Jain A, Cooney AL, Sinn PL, Pezzulo AA, Duffey ME, Welsh MJ. Am J Respir Cell Mol Biol. 2022 Jul 18. doi: 10.1165/rcmb.2022-0172OC. PMID: 35849656

July 16

The Role of Platelet-Derived Extracellular Vesicles in Immune-Mediated Thrombosis. Eustes AS, Dayal S. Int J Mol Sci. 2022 Jul 16;23(14):7837. doi: 10.3390/ijms23147837. PMID: 35887184. Review.

July 15

Atrial-paced, exercise-similar heart rate envelope induces myocardial protection from ischaemic injury. Zhu Z, Gao Z, Chen B, Hall DD, Minerath R, Koval O, Sierra A, Subbotina E, Zhu X, Kim YR, Yang J, Grumbach I, Irani K, Grueter C, Song LS, Hodgson-Zingman DM, Zingman LV. Europace. 2022 Jul 15;24(6):1025-1035. doi: 10.1093/europace/euab273. PMID: 34792112
Direct Caverno-Pleural Fistula Closure using an Amplatzer Vascular Plug. Gross TJ, Recker T, Keech JC, Horwitz PA. J Bronchology Interv Pulmonol. 2022 Jul 15. doi: 10.1097/LBR.0000000000000846. PMID: 35838177

July 12

Guidance for Cardiopulmonary Resuscitation of Children With Suspected or Confirmed COVID-19. Morgan RW, Atkins DL, Hsu A, Kamath-Rayne BD, Aziz K, Berg RA, Bhanji F, Chan M, Cheng A, Chiotos K, de Caen A, Duff JP, Fuchs S, Joyner BL Jr, Kleinman M, Lasa JJ, Lee HC, Lehotzky RE, Levy A, McBride ME, Meckler G, Nadkarni V, Raymond T, Roberts K, Schexnayder SM, Sutton RM, Terry M, Walsh B, Zelop CM, Sasson C, Topjian A. Pediatrics. 2022 Jul 12. doi: 10.1542/peds.2021-056043. PMID: 35818123
Long-term dietary intervention influence on physical activity in the Women's Health Initiative Dietary Modification randomized trial. Pan K, Aragaki AK, Michael Y, Thomson CA, Snetselaar LG, Wactawski-Wende J, Garcia DO, Dieli-Conwright CM, Shadyab AH, Saquib N, Chlebowski RT. Breast Cancer Res Treat. 2022 Jul 12. doi: 10.1007/s10549-022-06655-8. PMID: 35821536

July 8

More Evidence Links Microglia and Neuroinflammation With Hypertension. Cheng L, Correia MLG. Am J Hypertens. 2022 Jul 8:hpac081. doi: 10.1093/ajh/hpac081. PMID: 35815792
Sphingosine Phosphate Lyase Is Upregulated in Duchenne Muscular Dystrophy, and Its Inhibition Early in Life Attenuates Inflammation and Dystrophy in Mdx Mice. De la Garza-Rodea AS, Moore SA, Zamora-Pineda J, Hoffman EP, Mistry K, Kumar A, Strober JB, Zhao P, Suh JH, Saba JD. Int J Mol Sci. 2022 Jul 8;23(14):7579. doi: 10.3390/ijms23147579. PMID: 35886926
Ten-Year Changes in Television Viewing and Physical Activity Are Associated With Concurrent 10-Year Change in Pericardial Adiposity: The Coronary Artery Risk Development in Young Adults Study. Oh M, Jacobs DR, Gabriel KP, Bao W, Pierce GL, Carr LJ, Terry JG, Ding J, Carr JJ, Whitaker KM. J Phys Act Health. 2022 Jul 8:1-9. doi: 10.1123/jpah.2021-0726. PMID: 35894964

July 6

Assessing predictors of rheumatoid arthritis-associated interstitial lung disease using quantitative lung densitometry. Alevizos MK, Danoff SK, Pappas DA, Lederer DJ, Johnson C, Hoffman EA, Bernstein EJ, Bathon JM, Giles JT. Rheumatology (Oxford). 2022 Jul 6;61(7):2792-2804. doi: 10.1093/rheumatology/keab828. PMID: 34747452
Biomarker-Calibrated Red and Combined Red and Processed Meat Intakes with Chronic Disease Risk in a Cohort of Postmenopausal Women. Zheng C, Pettinger M, Gowda GAN, Lampe JW, Raftery D, Tinker LF, Huang Y, Navarro SL, O'Brien DM, Snetselaar L, Liu S, Wallace RB, Neuhouser ML, Prentice RL. J Nutr. 2022 Jul 6;152(7):1711-1720. doi: 10.1093/jn/nxac067. PMID: 35289908
Hypertensive disorders of pregnancy among women with a history of leukemia or lymphoma. Anand ST, Ryckman KK, Baer RJ, Charlton ME, Breheny PJ, Terry WW, McLemore MR, Karasek DA, Jelliffe-Pawlowski LL, Chrischilles EA. Pregnancy Hypertens. 2022 Jul 6;29:101-107. doi: 10.1016/j.preghy.2022.07.002. PMID: 35853379

July 5

Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice. McLendon JM, Zhang X, Matasic DS, Kumar M, Koval OM, Grumbach IM, Sadayappan S, London B, Boudreau RL. J Am Heart Assoc. 2022 Jul 5;11(13):e025687. doi: 10.1161/JAHA.122.025687. PMID: 35730644
Oxidative stress and impaired insulin secretion in cystic fibrosis pig pancreas. O'Malley Y, Coleman MC, Sun X, Lei J, Yao J, Pulliam CF, Kluz P, McCormick ML, Yi Y, Imai Y, Engelhardt JF, Norris AW, Spitz DR, Uc A. Adv Redox Res. 2022 Jul;5:100040. doi: 10.1016/j.arres.2022.100040. PMID: 35903252
Sex-Specific Differences in Endothelial Function Are Driven by Divergent Mitochondrial Ca²⁺ Handling. Damacena de Angelis C, Endoni BT, Nuno D, Lamping K, Ledolter J, Koval OM, Grumbach IM. J Am Heart Assoc. 2022 Jul 5;11(13):e023912. doi: 10.1161/JAHA.121.023912. PMID: 35766269

July 2

Associations of Health-Related Quality of Life and Sleep Disturbance With Cardiovascular Disease Risk in Postmenopausal Breast Cancer Survivors. Vasbinder A, Zaslavsky O, Heckbert SR, Thompson H, Cheng RK, Saquib N, Wallace RB, Haque R, Paskett ED, Reding KW. Cancer Nurs. 2022 Jul 2. doi: 10.1097/NCC.0000000000001133. PMID: 35816026

July 1

August 2022

August 31

Optimal Urine Culture Diagnostic Stewardship Practice-Results from an Expert Modified-Delphi Procedure. Claeys KC, Trautner BW, Leekha S, Coffey KC, Crnich CJ, Diekema DJ, Fakih MG, Goetz MB, Gupta K, Jones MM, Leykum L, Liang SY, Pineles L, Pleiss A, Spivak ES, Suda KJ, Taylor JM, Rhee C, Morgan DJ. Clin Infect Dis. 2022 Aug 31;75(3):382-389. doi: 10.1093/cid/ciab987. PMID: 348496379+

August 30

The effects of antidepressants on depressive symptoms in manifest Huntington's disease. Ogilvie AC, Carnahan RM, Chrischilles EA, Schultz JL. J Psychosom Res. 2022 Aug 30;162:111023. doi: 10.1016/j.jpsychores.2022.111023. PMID: 36063627
Hospital Rurality and Gene Expression Profiling for Early-Stage Breast Cancer among Iowa Residents (2010-2018). Riley D, Charlton M, Chrischilles EA, Lizarraga IM, Phadke S, Smith BJ, Skibbe A, Lynch CF. Breast J. 2022 Aug 30;2022:8582894. doi: 10.1155/2022/8582894. PMID: 36111211
A Pilot randomized trial to examine effects of a hybrid closed-loop insulin delivery system on neurodevelopmental and cognitive outcomes in adolescents with type 1 diabetes. Reiss AL, Jo B, Arbelaez AM, Tsalikian E, Buckingham B, Weinzimer SA, Fox LA, Cato A, White NH, Tansey M, Aye T, Tamborlane W, Englert K, Lum J, Mazaika P, Foland-Ross L, Marzelli M, Mauras N; Diabetes Research in Children Network (DirecNet) Consortium. Nat Commun. 2022 Aug 30;13(1):4940. doi: 10.1038/s41467-022-32289-x. PMID: 36042217

August 29

The Fibromyalgia Transcutaneous Electrical Nerve Stimulation in Physical Therapy Study (FM-TIPS) Protocol: A Multisite Embedded Pragmatic Trial. Post AA, Dailey DL, Bayman EO, Chimenti RL, Costigan M, Franck C, Huff T, Johnson E, Koepp M, Lafontant DE, McCabe ME, Neill-Hudson T, Vance CGT, Van Gorp B, Zimmerman BM, Ecklund D, Crofford LJ, Sluka KA. Phys Ther. 2022 Aug 29:pzac116. doi: 10.1093/ptj/pzac116. PMID: 36036838

August 25

Sox9 and Lef1 Regulate the Fate and Behavior of Airway Glandular Progenitors in Response to Injury. Ievlev V, Jensen-Cody CC, Lynch TJ, Pai AC, Park S, Shahin W, Wang K, Parekh KR, Engelhardt JF. Stem Cells. 2022 Aug 25;40(8):778-790. doi: 10.1093/stmcls/sxac038. PMID: 35639980
Understanding the Prodrome of Necrotizing Soft Tissue Infections of the Genitalia (Fournier's Gangrene) and the Incidence, Duration, and Risk Factors Associated with Potential Missed Opportunities for an Earlier Diagnosis: A Population-Based Longitudinal Study. Erickson BA, Miller AC, Warner HL, Drobish JN, Koeneman SH, Cavanaugh JE, Polgreen PM. J Urol. 2022 Aug 25:101097JU0000000000002920. doi: 10.1097/JU.0000000000002920. PMID: 36006046

August 23

Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity-related cancer risk and mortality in Black and Latina Women's Health Initiative participants. Pichardo MS, Esserman D, Ferrucci LM, Molina Y, Chlebowski RT, Pan K, Garcia DO, Lane DS, Shadyab AH, Lopez-Pentecost M, Luo J, Kato I, Springfield S, Rosal MC, Bea JW, Cespedes Feliciano EM, Qi L, Nassir R, Snetselaar L, Manson J, Bird C, Irwin ML. Cancer. 2022 Aug 23. doi: 10.1002/cncr.34428. PMID: 35996861
Central FGF21 production regulates memory but not peripheral metabolism. Zhou B, Claflin KE, Flippo KH, Sullivan AI, Asghari A, Tadinada SM, Jensen-Cody SO, Abel T, Potthoff MJ. Cell Rep. 2022 Aug 23;40(8):111239. doi: 10.1016/j.celrep.2022.111239. PMID: 36001982

August 22

The effect of gender and obesity in modulating cross-bridge function in cardiac muscle fibers. Xi J, Ye Y, Mokadem M, Yuan J, Kawai M. J Muscle Res Cell Motil. 2022 Aug 22. doi: 10.1007/s10974-022-09627-z. PMID: 35994221
Extracellular matrix stiffness controls cardiac valve myofibroblast activation through epigenetic remodeling. Walker CJ, Batan D, Bishop CT, Ramirez D, Aguado BA, Schroeder ME, Crocini C, Schwisow J, Moulton K, Macdougall L, Weiss RM, Allen MA, Dowell R, Leinwand LA, Anseth KS. Bioeng Transl Med. 2022 Aug 22;7(3):e10394. doi: 10.1002/btm2.10394. eCollection 2022 Sep. PMID: 36176599
FXYD3 facilitates Na⁺ and liquid absorption across human airway epithelia by increasing the transport capacity of the Na/K ATPase. Cano Portillo C, Villacreses R, Thurman AL, Pezzulo AA, Zabner J, Thornell IM. Am J Physiol Cell Physiol. 2022 Aug 22. doi: 10.1152/ajpcell.00047.2022. PMID: 35993520
Pharmacological ascorbate as a novel therapeutic strategy to enhance cancer immunotherapy. Zaher A, Stephens LM, Miller AM, Hartwig SM, Stolwijk JM, Petronek MS, Zacharias ZR, Wadas TJ, Monga V, Cullen JJ, Furqan M, Houtman JCD, Varga SM, Spitz DR, Allen BG.Front Immunol. 2022 Aug 22;13:989000. doi: 10.3389/fimmu.2022.989000. eCollection 2022. PMID: 36072595
Use of Glycolysis-Enhancing Drugs and Risk of Parkinson's Disease. Simmering JE, Welsh MJ, Schultz J, Narayanan NS. Mov Disord. 2022 Aug 22. doi: 10.1002/mds.29184. PMID: 36054705

August 19

Selective Serotonin Reuptake Inhibitor Use in Pregnancy and Protective Mechanisms in Preeclampsia. Vignato JA, Gumusoglu SB, Davis HA, Scroggins SM, Hamilton WS, Brandt DS, Pierce GL, Knosp BA, Santillan DA, Santillan MK. Reprod Sci. 2022 Aug 19. doi: 10.1007/s43032-022-01065-z. PMID: 35984571
Sustained over-expression of calpain-2 induces age-dependent dilated cardiomyopathy in mice through aberrant autophagy. Ji XY, Zheng D, Ni R, Wang JX, Shao JQ, Vue Z, Hinton A Jr, Song LS, Fan GC, Chakrabarti S, Su ZL, Peng TQ. Acta Pharmacol Sin. 2022 Aug 19. doi: 10.1038/s41401-022-00965-9. PMID: 35986214

August 17

Dynamin-Independent Mechanisms of Endocytosis and Receptor Trafficking. Gundu C, Arruri VK, Yadav P, Navik U, Kumar A, Amalkar VS, Vikram A, Gaddam RR. Cells. 2022 Aug 17;11(16):2557. doi: 10.3390/cells11162557. PMID: 36010634 Review.

August 16

A Glycosylated RBD Protein Induces Enhanced Neutralizing Antibodies against Omicron and Other Variants with Improved Protection against SARS-CoV-2 Infection. Shi J, Zheng J, Tai W, Verma AK, Zhang X, Geng Q, Wang G, Guan X, Malisheni MM, Odle AE, Zhang W, Li F, Perlman S, Du L. J Virol. 2022 Aug 16:e0011822. doi: 10.1128/jvi.00118-22. PMID: 35972290

August 15

Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102. Brashears CB, Prudner BC, Rathore R, Caldwell KE, Dehner CA, Buchanan JL, Lange SES, Poulin N, Sehn JK, Roszik J, Spitzer D, Jones KB, O'Keefe R, Nielsen TO, Taylor EB, Held JM, Hawkins W, Van Tine BA. Clin Cancer Res. 2022 Aug 15;28(16):3573-3589. doi: 10.1158/1078-0432.CCR-22-0470. PMID: 35421237
Vascular Findings in the Choriocapillaris in a Case of Radiation Retinopathy Secondary to Choroidal Melanoma. Binkley EM, Lozano LP, Riker MJ, Pennington EC, Tucker BA, Stone EM, Boldt HC, Mullins RF. Case Rep Ophthalmol. 2022 Aug 15;13(2):589-598. doi: 10.1159/000525568. eCollection 2022 May-Aug. PMID: 36160486

August 13

Proton Pump Inhibitor Use and Obesity-Associated Cancer in the Women's Health Initiative. Ballinger TJ, Djuric Z, Sardesai S, Hovey KM, Andrews CA, Brasky TM, Zhang JT, Rohan TE, Saquib N, Shadyab AH, Simon M, Wactawski-Wende J, Wallace R, Kato I. Nutr Cancer. 2022 Aug 13:1-11. doi: 10.1080/01635581.2022.2108467. PMID: 35968582

August 12

ASO Visual Abstract: Analysis of Breast Cancer Patients' Understanding and Worry About Lymphedema. Uhlmann RA, Mott SL, Curry M, Phadke S, Sugg SL, Erdahl LM, Weigel RJ, Lizarraga IM. Ann Surg Oncol. 2022 Aug 12. doi: 10.1245/s10434-022-12244-2. PMID: 35960453
Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with TRAF3 mutations. Rae W, Sowerby JM, Verhoeven D, Youssef M, Kotagiri P, Savinykh N, Coomber EL, Boneparth A, Chan A, Gong C, Jansen MH, du Long R, Santilli G, Simeoni I, Stephens J, Wu K, Zinicola M, Allen HL, Baxendale H, Kumararatne D, Gkrania-Klotsas E, Scheffler Mendoza SC, Yamazaki-Nakashimada MA, Ruiz LB, Rojas-Maruri CM, Lugo Reyes SO, Lyons PA, Williams AP, Hodson DJ, Bishop GA, Thrasher AJ, Thomas DC, Murphy MP, Vyse TJ, Milner JD, Kuijpers TW, Smith KGC. Sci Immunol. 2022 Aug 12;7(74):eabn3800. doi: 10.1126/sciimmunol.abn3800. PMID: 35960817
The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications. Selvadurai LP, Perlman SL, Wilmot GR, Subramony SH, Gomez CM, Ashizawa T, Paulson HL, Onyike CU, Rosenthal LS, Sair HI, Kuo SH, Ratai EM, Zesiewicz TA, Bushara KO, Öz G, Dietiker C, Geschwind MD, Nelson AB, Opal P, Yacoubian TA, Nopoulos PC, Shakkottai VG, Figueroa KP, Pulst SM, Morrison PE, Schmahmann JD. Cerebellum. 2022 Aug 12. doi: 10.1007/s12311-022-01424-1. PMID: 35962273

August 11

Association of low serum albumin with venous thrombosis in pediatric patients. Bhasin N, Roe DJ, Saboda K, Journeycake J, Moreno V, Lentz SR. Thromb Res. 2022 Aug 11;218:48-51. doi: 10.1016/j.thromres.2022.08.008. PMID: 35988444
Meal skipping and shorter meal intervals are associated with increased risk of all-cause and cardiovascular disease mortality among U.S. adults. Sun Y, Rong S, Liu B, Du Y, Wu Y, Chen L, Xiao Q, Snetselaar L, Wallace R, Bao W. J Acad Nutr Diet. 2022 Aug 11:S2212-2672(22)00874-7. doi: 10.1016/j.jand.2022.08.119. PMID: 35964910

August 10

E-cigarette or vaping product use-associated lung injury: A review of clinico-radio-pathological characteristics. Garg I, Vidholia A, Garg A, Singh S, Agahi A, Laroia A, Saboo SS, Comellas AP, Hoffman EA, Nagpal P. Respir Investig. 2022 Aug 10:S2212-5345(22)00092-2. doi: 10.1016/j.resinv.2022.06.011. PMID: 35963780. Review.
Lay rescuer use of automated external defibrillators in infants, children and adolescents: A systematic review. Atkins DL, Acworth J, Chung SP, Reis A, Van de Voorde P; International Liaison Committee on Resuscitation (ILCOR) Pediatric and Basic Life Support Task Forces. Resusc Plus. 2022 Aug 10;11:100283. doi: 10.1016/j.resplu.2022.100283. PMID: 35992959. Review

August 9

ASTRO supports access to evidence-based cancer care for all patients, regardless of pregnancy status, and protection for physicians recommending and providing evidence-based care. Jacobson GM, Bajaj GK, Buatti JM, Dawson L, Deville C, Eichler TJ, Erickson B, Ford E, Gibbs IC, Mantz C, Marples B, Michalski JM, Sandler H, Smith B, Vapiwala N, Yashar C. Int J Radiat Oncol Biol Phys. 2022 Aug 9:S0360-3016(22)02602-5. doi: 10.1016/j.ijrobp.2022.07.1844. PMID: 35963472

August 8

Pediatric infectious disease physician perceptions of antimicrobial stewardship programs. Lake JG, Durkin MJ, Polgreen PM, Beekmann SE, Hersh AL, Newland JG. Infect Control Hosp Epidemiol. 2022 Aug 8:1-4. doi: 10.1017/ice.2022.183. PMID: 35938450
Pulmonary Blood Volume Among Older Adults in the Community: The MESA Lung Study. Hermann EA, Motahari A, Hoffman EA, Allen N, Bertoni AG, Bluemke DA, Eskandari A, Gerard SE, Guo J, Hiura GT, Kaczka DW, Michos ED, Nagpal P, Pankow J, Shah S, Smith BM, Hinckley Stukovsky K, Sun Y, Watson K, Barr RG. Circ Cardiovasc Imaging. 2022 Aug 8:101161CIRCIMAGING122014380. doi: 10.1161/CIRCIMAGING.122.014380. PMID: 35938411

August 6

Effect of the STRIDE fall injury prevention intervention on falls, fall injuries, and health-related quality of life. Ganz DA, Yuan AH, Greene EJ, Latham NK, Araujo K, Siu AL, Magaziner J, Gurwitz JH, Wu AW, Alexander NB, Wallace RB, Greenspan SL, Rich J, Volpi E, Waring SC, Dykes PC, Ko F, Resnick NM, McMahon SK, Basaria S, Wang R, Lu C, Esserman D, Dziura J, Miller ME, Travison TG, Peduzzi P, Bhasin S, Reuben DB, Gill TM. J Am Geriatr Soc. 2022 Aug 6. doi: 10.1111/jgs.17964. PMID: 35932279
Pharmacological FGF21 Signals to Glutamatergic Neurons to Enhance Leptin Action and Lower Body Weight During Obesity. Claflin KE, Sullivan AI, Naber MC, Flippo KH, Morgan DA, Neff TJ, Jensen-Cody SO, Zhu Z, Zingman LV, Rahmouni K, Potthoff MJ. Mol Metab. 2022 Aug 6:101564. doi: 10.1016/j.molmet.2022.101564. PMID: 35944896

August 4

Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition. Li Y, Balakrishnan VK, Rowse M, Wu CG, Bravos AP, Yadav VK, Ivarsson Y, Strack S, Novikova IV, Xing Y. Elife. 2022 Aug 4;11:e79736. doi: 10.7554/eLife.79736. PMID: 35924897
Scylla, Charybdis, and navigating antimicrobial action in the neutrophil phagosome. Nauseef WM. J Leukoc Biol. 2022 Aug 4. doi: 10.1002/JLB.4CE0422-232R. PMID: 35929044
"Where are they now"? Catching up with the 2017 AAAAI Faculty Development Awardees. Ballas ZK. J Allergy Clin Immunol. 2022 Aug 4:S0091-6749(22)00994-0. doi: 10.1016/j.jaci.2022.06.026. PMID: 35934086

August 2

Association of Low-Density Lipoprotein Cholesterol Levels with More than 20-Year Risk of Cardiovascular and All-Cause Mortality in the General Population. Rong S, Li B, Chen L, Sun Y, Du Y, Liu B, Robinson JG, Bao W. J Am Heart Assoc. 2022 Aug 2;11(15):e023690. doi: 10.1161/JAHA.121.023690. PMID: 35904192
Occurrence and spatial distribution of individual polychlorinated biphenyl congeners in residential soils from East Chicago, southwest Lake Michigan. Martinez A, Hua J, Haque E, Hornbuckle KC, Thorne PS. Sci Total Environ. 2022 Aug 2:157705. doi: 10.1016/j.scitotenv.2022.157705. PMID: 35931157
Sex Differences in Airways at Chest CT: Results from the COPDGene Cohort. Bhatt SP, Bodduluri S, Nakhmani A, Kim YI, Reinhardt JM, Hoffman EA, Motahari A, Wilson CG, Humphries SM, Regan EA, DeMeo DL. Radiology. 2022 Aug 2:212985. doi: 10.1148/radiol.212985. PMID: 35916677

August 1

September 2022

September 30

Clinical Decision Support Systems to Reduce Unnecessary Clostridioides difficile Testing Across Multiple Hospitals. Rock C, Abosi O, Bleasdale S, Colligan E, Diekema DJ, Dullabh P, Gurses AP, Heaney-Huls K, Jacob JT, Kandiah S, Lama S, Leekha S, Mayer J, Mena Lora AJ, Morgan DJ, Osei P, Pau S, Salinas JL, Spivak E, Wenzler E, Cosgrove SE. Clin Infect Dis. 2022 Sep 30;75(7):1187-1193. doi: 10.1093/cid/ciac074. PMID: 35100620
Nonidentical function of Upc2A binding sites in the Candida glabrata CDR1 promoter. Vu BG, Moye-Rowley WS. Genetics. 2022 Sep 30;222(2):iyac135. doi: 10.1093/genetics/iyac135. PMID: 36063046
The Rapid Reduction of Infection-Related Visits and Antibiotic Use Among People With Cystic Fibrosis After Starting Elexacaftor-Tezacaftor-Ivacaftor. Miller AC, Harris LM, Cavanaugh JE, Abou Alaiwa M, Stoltz DA, Hornick DB, Polgreen PM. Clin Infect Dis. 2022 Sep 30;75(7):1115-1122. doi: 10.1093/cid/ciac117. PMID: 35142340
Translating Outcomes from the Clinical Setting to Preclinical Models: Chronic Pain and Functionality in Chronic Musculoskeletal Pain. Lenert ME, Gomez R, Lane BT, Dailey DL, Vance CGT, Rakel BA, Crofford LJ, Sluka KA, Merriwether EN, Burton MD. Pain Med. 2022 Sep 30;23(10):1690-1707. doi: 10.1093/pm/pnac047. PMID: 35325207

September 29

Characterization of a novel Pde6b-deficient rat model of retinal degeneration and treatment with adeno-associated virus (AAV) gene therapy. Han IC, Wiley LA, Ochoa D, Lang MJ, Harman BE, Sheehan KM, Mullins RF, Stone EM, Tucker BA. Gene Ther. 2022 Sep 29. doi: 10.1038/s41434-022-00365-y. PMID: 36175490
Striatal Development in Early-Onset Huntington's Disease. Schultz JL, Epping EA, van der Plas E, Magnotta VA, Nopoulos PC. Mov Disord. 2022 Sep 29. doi: 10.1002/mds.29227. PMID: 36177602

September 28

L-cysteine methyl ester overcomes the deleterious effects of morphine on ventilatory parameters and arterial blood-gas chemistry in unanesthetized rats. Getsy PM, Baby SM, May WJ, Bates JN, Ellis CR, Feasel MG, Wilson CG, Lewis THJ, Gaston B, Hsieh YH, Lewis SJ. Front Pharmacol. 2022 Sep 28;13:968378. doi: 10.3389/fphar.2022.968378. eCollection 2022. PMID: 36249760
OPA1 Regulates Lipid Metabolism and Cold-Induced Browning of White Adipose Tissue in Mice. Pereira RO, Olvera AC, Marti A, Fang S, White JR, Westphal M, Hewezi R, AshShareef ST, Pena LMG, Koneru J, Potthoff MJ, Abel ED. Diabetes. 2022 Sep 28:db220450. doi: 10.2337/db22-0450. PMID: 36170659

September 27

TRAF3 enhances type I interferon receptor signaling in T cells by modulating the phosphatase PTPN22. Hornick EL, Wallis AM, Bishop GA. Sci Signal. 2022 Sep 27;15(753):eabn5507. doi: 10.1126/scisignal.abn5507. PMID: 36166512

September 26

Hypoxia Offsets the Decline in Brachial Artery Flow-mediated Dilation Following Acute Inactivity. Hanson BE, Iwamoto E, Mouser BL, Miller KA, Casey DP. Am J Physiol Regul Integr Comp Physiol. 2022 Sep 26. doi: 10.1152/ajpregu.00161.2022. PMID: 36154488
Pulmonary neuroendocrine cells sense succinate to stimulate myoepithelial cell contraction. Yu W, Moninger TO, Rector MV, Stoltz DA, Welsh MJ. Dev Cell. 2022 Sep 26;57(18):2221-2236.e5. doi: 10.1016/j.devcel.2022.08.010. PMID: 36108628

September 25

The Role of Incarceration as a Risk Factor for Cognitive Impairment. Cox RJA, Wallace RB. J Gerontol B Psychol Sci Soc Sci. 2022 Sep 25:gbac138. doi: 10.1093/geronb/gbac138. PMID: 36153747

September 23

Aortic pressure-only wave separation analysis in adolescents: accuracy and associations with left ventricular mass index. Armstrong MK, Chirinos JA, Kapuku GK, Pierce GL. J Hum Hypertens. 2022 Sep 23. doi: 10.1038/s41371-022-00757-y. PMID: 36151308
Sleep, circadian rhythm characteristics and melatonin levels in later life adults with and without coronary artery disease. Moon C, Benson CJ, Albashayreh A, Perkhounkova Y, Burgess HJ. J Clin Sleep Med. 2022 Sep 23. doi: 10.5664/jcsm.10308. PMID: 36148612

September 22

Effect of marijuana smoking on lung function change in older ever tobacco smokers. Barjaktarevic I, Cooper CB, Shing T, Buhr RG, Hoffman EA, Woodruff PG, Drummond MB, Kanner RE, Han MK, Hansel NN, Bowler RP, Kinney GL, Jacobson S, Morris MA, Martinez FJ, Ohar J, Couper D, Tashkin DP. Eur Respir J. 2022 Sep 22;60(3):2201133. doi: 10.1183/13993003.01133-2022. PMID: 36137583
Using TENS for Pain Control: Update on the State of the Evidence. Vance CGT, Dailey DL, Chimenti RL, Van Gorp BJ, Crofford LJ, Sluka KA. Medicina (Kaunas). 2022 Sep 22;58(10):1332. doi: 10.3390/medicina58101332. PMID: 36295493

September 21

A clinically-guided unsupervised clustering approach to recommend symptoms of disease associated with diagnostic opportunities. Miller AC, Arakkal AT, Koeneman SH, Cavanaugh JE, Polgreen PM. Diagnosis (Berl). 2022 Sep 21. doi: 10.1515/dx-2022-0044. PMID: 36127310
miR204 potentially promotes non-alcoholic fatty liver disease by inhibition of cpt1a in mouse hepatocytes. Kim S, Lee I, Piao S, Nagar H, Choi SJ, Kim YR, Irani K, Jeon BH, Kim CS. Commun Biol. 2022 Sep 21;5(1):1002. doi: 10.1038/s42003-022-03945-1. PMID: 36130994
Proviral role of caspase-6 in coronavirus infections. Wong LR, Perlman S. Cell Res. 2022 Sep 21. doi: 10.1038/s41422-022-00728-5. PMID: 36131099

September 20

Characterizing Subjects Exposed to Humidifier Disinfectants Using Computed-Tomography-Based Latent Traits: A Deep Learning Approach. Li F, Choi J, Zhang X, Rajaraman PK, Lee CH, Ko H, Chae KJ, Park EK, Comellas AP, Hoffman EA, Lin CL. Int J Environ Res Public Health. 2022 Sep 20;19(19):11894. doi: 10.3390/ijerph191911894. PMID: 36231196
Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart. Riehle C, Weatherford ET, McCarty NS, Seei A, Jaishy BP, Manivel R, Galuppo P, Allamargot C, Hameed T, Boudreau RL, Bauersachs J, Weiss RM, Abel ED. Mol Cell Biol. 2022 Sep 20:e0016322. doi: 10.1128/mcb.00163-22. PMID: 36125265
Knockout of Bbs10 results in lack of cone electrical function and progressive retinal degeneration of rods and cones. Mayer SK, Thomas J, Helms M, Kothapalli A, Cherascu I, Salesevic A, Stalter E, Wang K, Datta P, Searby C, Seo S, Hsu Y, Bhattarai S, Sheffield VC, Drack AV. Dis Model Mech. 2022 Sep 20:dmm.049473. doi: 10.1242/dmm.049473. PMID: 36124545
Role of Calcitonin Gene-Related Peptide on the Gastrointestinal Symptoms of Migraine-Clinical Considerations: A Narrative Review. Ailani J, Kaiser EA, Mathew PG, McAllister P, Russo AF, Vélez C, Ramajo AP, Abdrabboh A, Xu C, Rasmussen S, Tepper SJ. Neurology. 2022 Sep 20:10.1212/WNL.0000000000201332. doi: 10.1212/WNL.0000000000201332. PMID: 36127137

September 19

SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice. El-Kafrawy SA, Odle A, Abbas AT, Hassan AM, Abdel-Dayem UA, Qureshi AK, Wong LR, Zheng J, Meyerholz DK, Perlman S, Zumla A, Azhar EI. PLoS Pathog. 2022 Sep 19;18(9):e1010782. doi: 10.1371/journal.ppat.1010782. PMID: 36121829

September 16

Modeling Human Cerebellar Development In Vitro in 2D Structure. Madencioglu DA, Kruth KA, Wassink TH, Magnotta VA, Wemmie JA, Williams AJ. J Vis Exp. 2022 Sep 16;(187). doi: 10.3791/64462. PMID: 36190246

September 15

Validation of a semi-automatic software for optical coherence tomography - analysis in heart transplanted patients. Jensen NM, Chen Z, Clemmensen TS, Neghabat O, Holck EN, Pazdernik M, Mogensen LJH, Wahle A, Sonka M, Eiskjær H. Int J Cardiovasc Imaging. 2022 Sep 15. doi: 10.1007/s10554-022-02722-9. PMID: 36109445
The Essential Role of the Choriocapillaris in Vision: Novel Insights from Imaging and Molecular Biology. Mulfaul K, Russell JF, Voigt AP, Stone EM, Tucker BA, Mullins RF. Annu Rev Vis Sci. 2022 Sep 15;8:33-52. doi: 10.1146/annurev-vision-100820-085958. PMID: 36108103. Review.

September 14

A Glycosylated RBD Protein Induces Enhanced Neutralizing Antibodies against Omicron and Other Variants with Improved Protection against SARS-CoV-2 Infection. Shi J, Zheng J, Tai W, Verma AK, Zhang X, Geng Q, Wang G, Guan X, Malisheni MM, Odle AE, Zhang W, Li F, Perlman S, Du L. J Virol. 2022 Sep 14;96(17):e0011822. doi: 10.1128/jvi.00118-22. PMID: 35972290
BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease. Mani AM, Dhanabalan K, Lamin V, Wong T, Singh MV, Dokun AO. Int J Mol Sci. 2022 Sep 14;23(18):10715. doi: 10.3390/ijms231810715. PMID: 36142618

September 13

Mapping Alveolar Oxygen Partial Pressure in COPD Using Hyperpolarized Helium-3: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study. Taskiran NP, Hiura GT, Zhang X, Barr RG, Dashnaw SM, Hoffman EA, Malinsky D, Oelsner EC, Prince MR, Smith BM, Sun Y, Sun Y, Wild JM, Shen W, Hughes EW. Tomography. 2022 Sep 13;8(5):2268-2284. doi: 10.3390/tomography8050190. PMID: 36136886
Pharmacological Ascorbate Enhances Chemotherapies in Pancreatic Ductal Adenocarcinoma. O'Leary BR, Ruppenkamp EK, Steers GJ, Du J, Carroll RS, Wagner BA, Buettner GR, Cullen JJ. Pancreas. 2022 Sep 13. doi: 10.1097/MPA.0000000000002086. PMID: 36099493

September 12

Effectiveness and Optimal Duration of Adjunctive Rifampin Treatment in the Management of Staphylococcus aureus Prosthetic Joint Infections After Debridement, Antibiotics, and Implant Retention. Suzuki H, Goto M, Nair R, Livorsi DJ, Sekar P, Ohl ME, Diekema DJ, Perencevich EN, Alexander B, Jones MP, McDaniel JS, Schweizer ML. Open Forum Infect Dis. 2022 Sep 12;9(9):ofac473. doi: 10.1093/ofid/ofac473. PMID: 36196299
Task-based validation and application of a scanner-specific CT simulator using an anthropomorphic phantom. Shankar SS, Felice N, Hoffman EA, Atha J, Sieren JC, Samei E, Abadi E. Med Phys. 2022 Sep 12. doi: 10.1002/mp.15967. PMID: 36097259

September 10

Days of Antibiotic Spectrum Coverage: A Novel Metric for Inpatient Antibiotic Consumption. Kakiuchi S, Livorsi DJ, Perencevich EN, Diekema DJ, Ince D, Prasidthrathsint K, Kinn P, Percival K, Heintz BH, Goto M. Clin Infect Dis. 2022 Sep 10;75(4):567-576. doi: 10.1093/cid/ciab1034. PMID: 34910130
Mouse tissue harvest-induced hypoxia rapidly alters the in vivo metabolome, between-genotype metabolite level differences, and ¹³C-tracing enrichments. Rauckhorst AJ, Borcherding N, Pape DJ, Kraus AS, Scerbo DA, Taylor EB. Mol Metab. 2022 Sep 10:101596. doi: 10.1016/j.molmet.2022.101596. PMID: 36100179
Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. Chheda PR, Nieto N, Kaur S, Beck JM, Beck JR, Honzatko R, Kerns RJ, Nelson SW. Eur J Med Chem. 2022 Sep 10;243:114751. doi: 10.1016/j.ejmech.2022.114751. PMID: 36191407

September 9

A Rare Presentation of New-Onset Type 1 Diabetes Mellitus in a Developmentally Delayed Child With an Overlap of Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State. Parra Villasmil MG, Patel S, Tansey M, Badheka A, Chegondi M. Cureus. 2022 Sep 9;14(9):e28983. doi: 10.7759/cureus.28983. PMID: 36237743

September 8

Pulmonary neuroendocrine cells sense succinate to stimulate myoepithelial cell contraction. Yu W, Moninger TO, Rector MV, Stoltz DA, Welsh MJ. Dev Cell. 2022 Sep 8:S1534-5807(22)00596-2. doi: 10.1016/j.devcel.2022.08.010. PMID: 36108628
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment. Sponagel J, Jones JK, Frankfater C, Zhang S, Tung O, Cho K, Tinkum KL, Gass H, Nunez E, Spitz DR, Chinnaiyan P, Schaefer J, Patti GJ, Graham MS, Mauguen A, Grkovski M, Dunphy MP, Krebs S, Luo J, Rubin JB, Ippolito JE. Med (N Y). 2022 Sep 8:S2666-6340(22)00365-8. doi: 10.1016/j.medj.2022.08.005. PMID: 36108629

September 7

KCB-Net: A 3D knee cartilage and bone segmentation network via sparse annotation. Peng Y, Zheng H, Liang P, Zhang L, Zaman F, Wu X, Sonka M, Chen DZ. Med Image Anal. 2022 Sep 7;82:102574. doi: 10.1016/j.media.2022.102574. PMID: 36126403
Sensitization of Hypertension: The Impact of Earlier Life Challenges: Excellence Award for Hypertension Research 2021. Xue B, Johnson AK. Hypertension. 2022 Sep 7:101161HYPERTENSIONAHA12218550. doi: 10.1161/HYPERTENSIONAHA.122.18550. PMID: 36069195. Review.

September 6

PRC2 loss drives MPNST metastasis and matrix remodeling. Brockman QR, Scherer A, McGivney GR, Gutierrez WR, Voigt AP, Isaacson AL, Laverty EA, Roughton G, Knepper-Adrian V, Darbro B, Tanas MR, Stipp CS, Dodd RD. JCI Insight. 2022 Sep 6:e157502. doi: 10.1172/jci.insight.157502. PMID: 36066973

September 5

A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia. Rodden LN, Rummey C, Dong YN, Lagedrost S, Regner S, Brocht A, Bushara K, Delatycki MB, Gomez CM, Mathews K, Murray S, Perlman S, Ravina B, Subramony SH, Wilmot G, Zesiewicz T, Bolotta A, Domissy A, Jespersen C, Ji B, Soragni E, Gottesfeld JM, Lynch DR. Front Mol Biosci. 2022 Sep 5;9:933788. doi: 10.3389/fmolb.2022.933788. PMID: 36133907
Nonidentical function of Upc2A binding sites in the Candida glabrata CDR1 promoter. Vu BG, Moye-Rowley WS. Genetics. 2022 Sep 5:iyac135. doi: 10.1093/genetics/iyac135. PMID: 36063046

September 2

PERSPECTIVE: A Proposal To Name Four Coronaviruses of Limited Virulence "Common Cold Coronaviruses". McIntosh K, Perlman S, Monto A, Englund JA. J Infect Dis. 2022 Sep 2:jiac355. doi: 10.1093/infdis/jiac355. PMID: 36052654

September 1

October 2022

October 31

Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses. Gaziano L, Sun L, Arnold M, Bell S, Cho K, Kaptoge SK, Song RJ, et al…..Wallace RB, Emerging Risk Factors Collaboration/EPIC-CVD/Million Veteran Program. Circulation. 2022 Oct 31. doi: 10.1161/CIRCULATIONAHA.122.060700. PMID: 36314129

October 25

Effects of Combined Inorganic Nitrate and Nitrite Supplementation on Cardiorespiratory Fitness and Skeletal Muscle Oxidative Capacity in Type 2 Diabetes: A Pilot Randomized Controlled Trial. Turner KD, Kronemberger A, Bae D, Bock, JM, Hughes WE, Ueda K, Feider AJ, Hanada S, de Sousa LGO, Harris, MP, Anderson EJ, Bodine SC, Zimmerman MB, Casey DP, Lira VA. Nutrients. 2022 Oct 25;14(21):4479. doi: 10.3390/nu14214479. PMID: 36364742
Elucidating the role of Rgs2 expression in the PVN for metabolic homeostasis in mice. Deng Y, Dickey JE, Saito K, Deng G, Singh U, Jiang J, Toth BA, Zhu Z, Zingman LV, Resch JM, Grobe JL, Cui H. Mol Metab. 2022 Oct 25:101622. doi: 10.1016/j.molmet.2022.101622. PMID: 36307046

October 24

PRC2 loss drives MPNST metastasis and matrix remodeling. Brockman QR, Scherer A, McGivney GR, Gutierrez WR, Voigt AP, Isaacson AL, Laverty EA, Roughton G, Knepper-Adrian V, Darbro B, Tanas MR, Stipp CS, Dodd RD. JCI Insight. 2022 Oct 24;7(20):e157502. doi: 10.1172/jci.insight.157502. PMID: 36066973

October 23

Hypomorphism of a Novel Long ERα Isoform Causes Severe Reproductive Dysfunctions in Female Mice. Saito K, Dickey JE, Rodeghiero SR, Toth BA, Kelly MJ, Deng Y, Singh U, Deng G, Jiang J, Cui H. Endocrinology. 2022 Oct 23;163(12):bqac160. doi: 10.1210/endocr/bqac160. PMID: 36181426

October 21

Development and Characterization of a New Monoclonal Antibody against SARS-CoV-2 NSP12. Meng W, Guo S, Cao S, Shuda M, Robinson-McCarthy LR, McCarthy KR, Shuda Y, Paniz Mondolfi AE, Bryce C, Grimes Z, Sordillo EM, Cordon-Cardo C, Li P, Zhang H, Perlman S, Guo H, Gao SJ, Chang Y, Moore PS. J Med Virol. 2022 Oct 21. doi: 10.1002/jmv.28246. PMID: 36271490
Introduction to Special Collection Issue Interdisciplinary Aging Research to Address Health Disparities in Alzheimer's Disease and Related Dementias: A Scientific Training Program for Early-Career Scholars. Aranda MP, Wallace RB. J Gerontol B Psychol Sci Soc Sci. 2022 Oct 21:gbac170. doi: 10.1093/geronb/gbac170. PMID: 36268780
Plasticity of Cerebral Microvascular Structure and Mechanics During Hypertension and Following Recovery of Arterial Pressure. Sabharwal R, Chapleau MW, Gerhold TD, Baumbach GL, Faraci FM. Am J Physiol Heart Circ Physiol. 2022 Oct 21. doi: 10.1152/ajpheart.00292.2022. PMID: 36269650
SRC-RAC1 signaling drives drug resistance to BRAF inhibition in de-differentiated cutaneous melanomas. Zhu EY, Riordan JD, Vanneste M, Henry MD, Stipp CS, Dupuy AJ. NPJ Precis Oncol. 2022 Oct 21;6(1):74. doi: 10.1038/s41698-022-00310-7. PMID: 36271142

October 20

Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart. Riehle C, Weatherford ET, McCarty NS, Seei A, Jaishy BP, Manivel R, Galuppo P, Allamargot C, Hameed T, Boudreau RL, Bauersachs J, Weiss RM, Abel ED. Mol Cell Biol. 2022 Oct 20;42(10):e0016322. doi: 10.1128/mcb.00163-22. PMID: 36125265

October 19

Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice. Ritter ML, Deng G, Reho JJ, Deng Y, Sapouckey SA, Opichka MA, Balapattabi K, Wackman KK, Brozoski DT, Lu KT, Paradee WJ, Gibson-Corley KN, Cui H, Nakagawa P, Morselli LL, Sigmund CD, Grobe JL. Hypertension. 2022 Oct 19. doi: 10.1161/HYPERTENSIONAHA.122.20169. PMID: 36259376
Metabolic clearance of oxaloacetate and mitochondrial complex II respiration: Divergent control in skeletal muscle and brown adipose tissue. Yu L, Fink BD, Som R, Rauckhorst AJ, Taylor EB, Sivitz WI. Biochim Biophys Acta Bioenerg. 2022 Oct 19:148930. doi: 10.1016/j.bbabio.2022.148930. PMID: 36272463

October 18

Efficacy of Diet on Fatigue and Quality of Life in Multiple Sclerosis: A Systematic Review and Network Meta-analysis of Randomized Trials. Snetselaar L, Cheek JJ, Fox SS, Healy HS, Schweizer ML, Bao W, Kamholz J, Titcomb TJ. Neurology. 2022 Oct 18:10.1212/WNL.0000000000201371. doi: 10.1212/WNL.0000000000201371. PMID: 36257717
Pandemic origins and a One Health approach to preparedness and prevention: Solutions based on SARS-CoV-2 and other RNA viruses. Keusch GT, Amuasi JH, Anderson DE, Daszak P, Eckerle I, Field H, Koopmans M, Lam SK, Das Neves CG, Peiris M, Perlman S, Wacharapluesadee S, Yadana S, Saif L. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2202871119. doi: 10.1073/pnas.2202871119. PMID: 36215506. Review.

October 17

CT-derived vessel segmentation for analysis of post-radiation therapy changes in vasculature and perfusion. Wuschner AE, Flakus MJ, Wallat EM, Reinhardt JM, Shanmuganayagam D, Christensen GE, Gerard SE, Bayouth JE. Front Physiol. 2022 Oct 17;13:1008526. doi: 10.3389/fphys.2022.1008526. PMID: 36324304

October 15

Intoxicating effects of alcohol depend on acid-sensing ion channels. Harmata GIS, Chan AC, Merfeld MJ, Taugher-Hebl RJ, Harijan AK, Hardie JB, Fan R, Long JD, Wang GZ, Dlouhy BJ, Bera AK, Narayanan NS, Wemmie JA. Neuropsychopharmacology. 2022 Oct 15. doi: 10.1038/s41386-022-01473-4. PMID: 36243771

October 14

The Tumor Suppressor Protein TRAF3 Modulates GSK3 Activity and Susceptibility of B Lymphoma Cells to GSK3 Inhibition. Hornick EL, Stunz LL, Sabree S, Wu X, Witzig TE, Bishop GA. Cancers (Basel). 2022 Oct 14;14(20):5029. doi: 10.3390/cancers14205029. PMID: 36291813

October 13

Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism. Gutierrez WR, Scherer A, Rytlewski JD, Laverty EA, Sheehan AP, McGivney GR, Brockman QR, Knepper-Adrian V, Roughton GA, Quelle DE, Gordon DJ, Monga V, Dodd RD. JCI Insight. 2022 Oct 13:e159419. doi: 10.1172/jci.insight.159419. PMID: 36227698
Brain Interleukin-17A contributes to neuroinflammation and cardiac dysfunction in rats with myocardial infarction. Yu Y, Weiss RM, Wei SG. Front Neurosci. 2022 Oct 13;16:1032434. doi: 10.3389/fnins.2022.1032434. eCollection 2022. PMID: 36312009
Involvement of the cerebellum in migraine. Wang M, Tutt JO, Dorricott NO, Parker KL, Russo AF, Sowers LP. Front Syst Neurosci. 2022 Oct 13;16:984406. doi: 10.3389/fnsys.2022.984406. eCollection 2022. PMID: 36313527

October 12

A saturated map of common genetic variants associated with human height. Yengo L, London B, et al, 23andMe Research Team; VA Million Veteran Program; DiscovEHR (DiscovEHR and MyCode Community Health Initiative); eMERGE (Electronic Medical Records and Genomics Network); Lifelines Cohort Study; PRACTICAL Consortium; Understanding Society Scientific Group, Chasman DI, Cho YS, Heid IM, McCarthy MI, Ng MCY, O'Donnell CJ, Rivadeneira F, Thorsteinsdottir U, Sun YV, Tai ES, Boehnke M, Deloukas P, Justice AE, Lindgren CM, Loos RJF, Mohlke KL, North KE, Stefansson K, Walters RG, Winkler TW, Young KL, Loh PR, Yang J, Esko T, Assimes TL, Auton A, Abecasis GR, Willer CJ, Locke AE, Berndt SI, Lettre G, Frayling TM, Okada Y, Wood AR, Visscher PM, Hirschhorn JN. Nature. 2022 Oct 12. doi: 10.1038/s41586-022-05275-y. PMID: 36224396

October 11

Contrastive learning and subtyping of post-COVID-19 lung computed tomography images. Li F, Zhang X, Comellas AP, Hoffman EA, Yang T, Lin CL. Front Physiol. 2022 Oct 11;13:999263. doi: 10.3389/fphys.2022.999263. eCollection 2022. PMID: 36304574
A Task-Specific Algorithm to Estimate Occupational (1→3)-β-D-glucan Exposure for Farmers in the Biomarkers of Exposure and Effect in Agriculture Study. Friesen MC, Hung F, Xie S, Viet SM, Deziel NC, Locke SJ, Josse PR, Sauvé JF, Andreotti G, Thorne PS, Beane-Freeman LE, Hofmann JN. Ann Work Expo Health. 2022 Oct 11;66(8):974-984. doi: 10.1093/annweh/wxac041. PMID: 35731645

October 10

Manipulation of Redox Metabolism using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-sensitization by ATM Inhibitors in Colorectal Cancer. Callaghan CM, Abukhiran IM, Masaadeh A, Van Rheeden RV, Kalen AL, Rodman SN 3rd, Petronek MS, Mapuskar KA, George BN, Coleman MC, Goswami PC, Allen BG, Spitz DR, Caster JM. Int J Radiat Oncol Biol Phys. 2022 Oct 10:S0360-3016(22)03438-1. doi: 10.1016/j.ijrobp.2022.10.012. PMID: 36228747
A Matched Survival Analysis of Lung Transplant Recipients with Covid-19-related Respiratory Failure. Freischlag K, Lynch TJ, Ievlev V, Gries C, Keech JC, Arshava EV, Pena T, Klesney-Tait JA, Parekh KR. Ann Thorac Surg. 2022 Oct 10:S0003-4975(22)01314-5. doi: 10.1016/j.athoracsur.2022.09.039. PMID: 36228676

October 7

Autonomic changes in Huntington's disease correlate with altered central autonomic network connectivity. Schultz JL, Heinzerling AE, Brinker AN, Harshman LA, Magnotta VA, Kamholz JA, Boes AD, Nopoulos PC. Brain Commun. 2022 Oct 7;4(5):fcac253. doi: 10.1093/braincomms/fcac253. PMID: 36324870
Targeting Cholesterol Homeostasis Improves Recovery in Experimental Optic Neuritis. Godwin CR, Anders JJ, Cheng L, Elwood BW, Kardon RH, Gramlich OW. Biomolecules. 2022 Oct 7;12(10):1437. doi: 10.3390/biom12101437. PMID: 36291646

October 4

CT-based lung motion differences in patients with usual interstitial pneumonia and nonspecific interstitial pneumonia. Choi J, Chae KJ, Jin GY, Lin CL, Laroia AT, Hoffman EA, Lee CH. Front Physiol. 2022 Oct 4;13:867473. doi: 10.3389/fphys.2022.867473. eCollection 2022. PMID: 36267579
Skeletal Muscle Adiposity and Lung Function Trajectory in the Severe Asthma Research Program (SARP). Tattersall MC, Lee KE, Tsuchiya N, Osman F, Korcarz CE, Hansen KM, Peters MC, Fahy JV, Longhurst CA, Dunican E, Wentzel SE, Leader JK, Israel E, Levy BD, Castro M, Erzurum SC, Lempel J, Moore W, Bleecker E, Phillips BR, Mauger DT, Hoffman EA, Fain SB, Reeder SB, Sorkness RL, Jarjour NN, Denlinger LC, Schiebler ML. Am J Respir Crit Care Med. 2022 Oct 4. doi: 10.1164/rccm.202203-0597OC. PMID: 36194556

October 1

November 2022

November 29

Efficacy of Omaveloxolone in Friedreich's Ataxia: Delayed-Start Analysis of the MOXIe Extension. Lynch DR, Chin MP, Boesch S, Delatycki MB, Giunti P, Goldsberry A, Hoyle JC, Mariotti C, Mathews KD, Nachbauer W, O'Grady M, Perlman S, Subramony SH, Wilmot G, Zesiewicz T, Meyer CJ.Mov Disord. 2022 Nov 29. doi: 10.1002/mds.29286. PMID: 36444905

November 28

Lipoprotein(a) in Youth and Prediction of Major Cardiovascular Outcomes in Adulthood. Raitakari O, Kartiosuo N, Pahkala K, Hutri-Kähönen N, Bazzano LA, Chen W, Urbina EM, Jacobs DR Jr, Sinaiko A, Steinberger J, Burns T, Daniels SR, Venn A, Woo JG, Dwyer T, Juonala M, Viikari J. Circulation. 2022 Nov 28. doi: 10.1161/CIRCULATIONAHA.122.060667. PMID: 36440577

November 23

The Fatty Acid Imbalance of Cystic Fibrosis Exists at Birth Independent of Feeding, in Pig and Ferret Models. Uc A, Strandvik B, Yao J, Liu X, Yi Y, Sun X, Welti R, Engelhardt JF, Norris AW. Clin Sci (Lond). 2022 Nov 23:CS20220450. doi: 10.1042/CS20220450. PMID: 36416119

November 22

Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism. Gutierrez WR, Scherer A, Rytlewski JD, Laverty EA, Sheehan AP, McGivney GR, Brockman QR, Knepper-Adrian V, Roughton GA, Quelle DE, Gordon DJ, Monga V, Dodd RD. JCI Insight. 2022 Nov 22;7(22):e159419. doi: 10.1172/jci.insight.159419. PMID: 36227698

November 18

Carbonic anhydrase 4 disruption decreases synaptic and behavioral adaptations induced by cocaine withdrawal. Gupta SC, Ghobbeh A, Taugher-Hebl RJ, Fan R, Hardie JB, LaLumiere RT, Wemmie JA. Sci Adv. 2022 Nov 18;8(46):eabq5058. doi: 10.1126/sciadv.abq5058. Epub 2022 Nov 16. PMID: 36383659

November 17

Anesthesia and the renal sympathetic nervous system in perioperative AKI. Franzén S, DiBona G, Frithiof R. Semin Nephrol. 2022 Nov 17:151283. doi: 10.1016/j.semnephrol.2022.10.009. PMID: 36404210. Review.

November 16

Acute Left Atrial Appendage Thrombus Formation During Transcatheter Mitral Valve Edge-to-Edge Repair. Sharma V, Horwitz PA, Rossen JD, El Accaoui RN. JACC Case Rep. 2022 Nov 16;4(22):1475-1479. doi: 10.1016/j.jaccas.2022.08.046. PMID: 36444181
Miyoshi Muscular Dystrophy Due to Novel Splice Site Variants in DYSF Gene. Bryant G, Moore SA, Nix JS, Rice G, Gokden M, Veerapandiyan A. Child Neurol Open. 2022 Nov 16;9:2329048X221140298. doi: 10.1177/2329048X221140298. PMID: 36419651
Robust Measures of Image-Registration-Derived Lung Biomechanics in SPIROMICS. Pan Y, Wang D, Chaudhary MFA, Shao W, Gerard SE, Durumeric OC, Bhatt SP, Barr RG, Hoffman EA, Reinhardt JM, Christensen GE. J Imaging. 2022 Nov 16;8(11):309. doi: 10.3390/jimaging8110309. PMID: 36422058

November 15

November 14

Biochemical Identification of a Nuclear Coactivator Protein Required for AtrR-Dependent Gene Regulation in Aspergillus fumigatus. Paul S, Ror S, McDonald WH, Moye-Rowley WS. mSphere. 2022 Nov 14:e0047622. doi: 10.1128/msphere.00476-22. PMID: 36374043
Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS. Tejwani V, Woo H, Liu C, Tillery AK, Gassett AJ, Kanner RE, Hoffman EA, Martinez FJ, Woodruff PG, Barr RG, Fawzy A, Koehler K, Curtis JL, Freeman CM, Cooper CB, Comellas AP, Pirozzi C, Paine R, Tashkin D, Krishnan JA, Sack C, Putcha N, Paulin LM, Zusman M, Kaufman JD, Alexis NE, Hansel NN. Respir Res. 2022 Nov 14;23(1):310. doi: 10.1186/s12931-022-02225-0. PMID: 36376879
Bronchodilator Responsiveness in Tobacco-Exposed Persons with or without COPD. Fortis S, Quibrera PM, Comellas AP, Bhatt SP, Tashkin DP, Hoffman EA, Criner GJ, Han MK, Barr RG, Arjomandi M, Dransfield MB, Peters SP, Dolezal BA, Kim V, Putcha N, Rennard SI, Paine R 3rd, Kanner RE, Curtis JL, Bowler RP, Martinez FJ, Hansel NN, Krishnan JA, Woodruff PG, Barjaktarevic IZ, Couper D, Anderson WH, Cooper CB. Chest. 2022 Nov 14:S0012-3692(22)04077-6. doi: 10.1016/j.chest.2022.11.009. PMID: 36395858

November 13

Earlier treatment in adults with high lifetime risk of cardiovascular diseases: What prevention trials are feasible and could change clinical practice? Report of a National Heart, Lung, and Blood Institute (NHLBI) Workshop. Navar AM, Fine LJ, Ambrosius WT, Brown A, Douglas PS, Johnson K, Khera AV, Lloyd-Jones D, Michos ED, Mujahid M, Muñoz D, Nasir K, Redmond N, Ridker PM, Robinson J, Schopfer D, Tate DF, Lewis CE. Am J Prev Cardiol. 2022 Nov 13;12:100430. doi: 10.1016/j.ajpc.2022.100430. PMID: 36439649

November 11

Influenza vaccination during pregnancy and risk of selected major structural congenital heart defects, National Birth Defects Prevention Study 2006-2011. Palmsten K, Suhl J, Conway KM, Kharbanda EO, Scholz TD, Ailes EC, Cragan JD, Nestoridi E, Papadopoulos EA, Kerr SM, Young SG, Olson C, Romitti PA; National Birth Defects Prevention Study. Birth Defects Res. 2022 Nov 11. doi: 10.1002/bdr2.2114. PMID: 36369789
Isolated Effects of Plasma Freezing versus Thawing on Metabolite Stability. Buchanan JL, Tormes Vaquerano J, Taylor EB. Metabolites. 2022 Nov 11;12(11):1098. doi: 10.3390/metabo12111098. PMID: 36422241
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment. Sponagel J, Jones JK, Frankfater C, Zhang S, Tung O, Cho K, Tinkum KL, Gass H, Nunez E, Spitz DR, Chinnaiyan P, Schaefer J, Patti GJ, Graham MS, Mauguen A, Grkovski M, Dunphy MP, Krebs S, Luo J, Rubin JB, Ippolito JE. Med (N Y). 2022 Nov 11;3(11):792-811.e12. doi: 10.1016/j.medj.2022.08.005. PMID: 36108629

November 10

Changes in Dietary Intake of Methionine, Folate/Folic Acid and Vitamin B12 and Survival in Postmenopausal Women with Breast Cancer: A Prospective Cohort Study. Sun Y, Fowke JH, Liang X, Mozhui K, Sen S, Bao W, Liu B, Snetselaar LG, Wallace RB, Shadyab AH, Saquib N, Cheng TD, Johnson KC. Nutrients. 2022 Nov 10;14(22):4747. doi: 10.3390/nu14224747. PMID: 36432434

November 9

Reducing brain TACE activity improves neuroinflammation and cardiac function in heart failure rats. Yu Y, Xue B, Irfan NM, Beltz T, Weiss RM, Johnson AK, Felder RB, Wei SG. Front Physiol. 2022 Nov 9;13:1052304. doi: 10.3389/fphys.2022.1052304. PMID: 36439267

November 7

Dietary patterns and urinary phthalate exposure among postmenopausal women of the Women's Health Initiative. Vieyra G, Hankinson SE, Oulhote Y, Vandenberg L, Tinker L, Mason J, Shadyab AH, Wallace R, Arcan C, Chen JC, Reeves KW. Environ Res. 2022 Nov 7;216(Pt 3):114727. doi: 10.1016/j.envres.2022.114727. PMID: 36356671
Initial clinical applications treating pediatric and adolescent patients using MR-guided radiotherapy. Kozak MM, Crompton D, Gross BA, Harshman L, Dickens D, Snyder J, Shepard A, St-Aubin J, Dunkerley D, Hyer D, Buatti JM. Front Oncol. 2022 Nov 7;12:962926. doi: 10.3389/fonc.2022.962926. PMID: 36419881
Prepregnancy exposure to dietary arsenic and congenital heart defects. Suhl J, Conway KM, Rhoads A, Langlois PH, Feldkamp ML, Michalski AM, Oleson J, Sidhu A, Scholz TD, Kancherla V, Obrycki J, Mazumdar M, Romitti PA; National Birth Defects Prevention Study. Birth Defects Res. 2022 Nov 7. doi: 10.1002/bdr2.2110. PMID: 36341763

November 5

Elucidating the neurological mechanism of the FLASH effect in juvenile mice exposed to hypofractionated radiotherapy. Allen BD, Alaghband Y, Kramár EA, Ru N, Petit B, Grilj V, Petronek MS, Pulliam CF, Kim RY, Doan NL, Baulch JE, Wood MA, Bailat C, Spitz DR, Vozenin MC, Limoli CL. Neuro Oncol. 2022 Nov 5:noac248. doi: 10.1093/neuonc/noac248. PMID: 36334265

November 3

Eight weeks of inorganic nitrate/nitrite supplementation improves aerobic exercise capacity and the gas exchange threshold in patients with type 2 diabetes. Bock JM, Hanson BE, Miller KA, Seaberg NT, Ueda K, Feider AJ, Hanada S, Lira VA, Casey DP. J Appl Physiol (1985). 2022 Nov 3. doi: 10.1152/japplphysiol.00478.2022. Online ahead of print. PMID: 36326473
Endogenous SOD2 (Superoxide Dismutase) Regulates Platelet-Dependent Thrombin Generation and Thrombosis During Aging. Sonkar VK, Eustes AS, Ahmed A, Jensen M, Solanki MV, Swamy J, Kumar R, Fidler TP, Houtman JCD, Allen BG, Spitz DR, Abel ED, Dayal S. Arterioscler Thromb Vasc Biol. 2022 Nov 3. doi: 10.1161/ATVBAHA.121.317735. PMID: 36325902
Energy metabolism and syncope. Rahmouni K. Clin Auton Res. 2022 Nov 3. doi: 10.1007/s10286-022-00906-w. PMID: 36326945
Generating Practice-Based Evidence in the Use of Guideline-Recommended Combination Therapy for Secondary Prevention of Acute Myocardial Infarction. Schroeder MC, Chapman CG, Chrischilles EA, Wilwert J, Schneider KM, Robinson JG, Brooks JM. Pharmacy (Basel). 2022 Nov 3;10(6):147. doi: 10.3390/pharmacy10060147. PMID: 36412823

November 1

December 2022

December 29

Interdisciplinary Aging Research to Address Health Disparities in Alzheimer's Disease and Related Dementias: A Scientific Training Program for Early-Career Scholars. Aranda MP, Wallace RB. J Gerontol B Psychol Sci Soc Sci. 2022 Dec 29;77(12):e199-e202. doi: 10.1093/geronb/gbac170. PMID: 36268780
The Role of Incarceration as a Risk Factor for Cognitive Impairment. Cox RJA, Wallace RB. J Gerontol B Psychol Sci Soc Sci. 2022 Dec 29;77(12):e247-e262. doi: 10.1093/geronb/gbac138. PMID: 36153747
The role of mitochondria in pharmacological ascorbate-induced toxicity. Du J, Pope AN, O'Leary BR, Wagner BA, Goswami PC, Buettner GR, Cullen JJ. Sci Rep. 2022 Dec 29;12(1):22521. doi: 10.1038/s41598-022-27185-9. PMID: 36581766

December 27

Rigid respiration: fulminant pulmonary fibrosis after COVID-19. Meyerholz DK. EBioMedicine. 2022 Dec 27;87:104428. doi: 10.1016/j.ebiom.2022.104428. PMID: 36580850

December 22

The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models. Uc A, Strandvik B, Yao J, Liu X, Yi Y, Sun X, Welti R, Engelhardt JF, Norris AW. Clin Sci (Lond). 2022 Dec 22;136(24):1773-1791. doi: 10.1042/CS20220450. PMID: 36416119
SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways. Verma AK, Zheng J, Meyerholz DK, Perlman S. JCI Insight. 2022 Dec 22;7(24):e160277. doi: 10.1172/jci.insight.160277. PMID: 36378534

December 21

Biochemical Identification of a Nuclear Coactivator Protein Required for AtrR-Dependent Gene Regulation in Aspergillus fumigatus. Paul S, Ror S, McDonald WH, Moye-Rowley WS. mSphere. 2022 Dec 21;7(6):e0047622. doi: 10.1128/msphere.00476-22. PMID: 36374043

December 20

Development and Validation of a Western Blot Method to Quantify Mini-Dystrophin in Human Skeletal Muscle Biopsies. Soderstrom CI, Larsen J, Owen C, Gifondorwa D, Beidler D, Yong FH, Conrad P, Neubert H, Moore SA, Hassanein M. AAPS J. 2022 Dec 20;25(1):12. doi: 10.1208/s12248-022-00776-0. PMID: 36539515
JAHA: The End of the Beginning. London B. J Am Heart Assoc. 2022 Dec 20;11(24):e028938. doi: 10.1161/JAHA.122.028938. PMID: 36515234
Novel Machine Learning Approach to Predict and Personalize Length of Stay for Patients Admitted with Syncope from the Emergency Department. Lee S, Reddy Mudireddy A, Kumar Pasupula D, Adhaduk M, Barsotti EJ, Sonka M, Statz GM, Bullis T, Johnston SL, Evans AZ, Olshansky B, Gebska MA. J Pers Med. 2022 Dec 20;13(1):7. doi: 10.3390/jpm13010007. PMID: 36675668

December 19

Childhood adiposity, serum metabolites and breast density in young women. Dorgan JF, Baer HJ, Bertrand KA, LeBlanc ES, Jung S, Magder LS, Snetselaar LG, Stevens VJ, Zhang Y, Van Horn L. Breast Cancer Res. 2022 Dec 19;24(1):91. doi: 10.1186/s13058-022-01588-y.PMID: 36536390
Chocolate consumption in relation to all-cause and cause-specific mortality in women: the Women's Health Initiative. Sun Y, Liu B, Snetselaar LG, Wallace RB, Shadyab AH, Chen GC, Shikany JM, Manson JE, Bao W. J Acad Nutr Diet. 2022 Dec 19:S2212-2672(22)01256-4. doi: 10.1016/j.jand.2022.12.007. PMID: 36549566
Comparison of the ketogenic ratio of macronutrients with the low-carbohydrate diet score and their association with risk of type 2 diabetes in postmenopausal women: A secondary analysis of the women's health initiative. Titcomb TJ, Liu B, Wahls TL, Snetselaar LG, Shadyab AH, Tabung FK, Saquib N, Arcan C, Tinker LF, Wallace RB, Bao W. J Acad Nutr Diet. 2022 Dec 19:S2212-2672(22)01253-9. doi: 10.1016/j.jand.2022.12.004. PMID: 36549565
Effective vaccination strategy using SARS-CoV-2 spike cocktail against Omicron and other variants of concern. Shi J, Wang G, Zheng J, Verma AK, Guan X, Malisheni MM, Geng Q, Li F, Perlman S, Du L. NPJ Vaccines. 2022 Dec 19;7(1):169. doi: 10.1038/s41541-022-00580-z.PMID: 36535987
T Cell-Specific Deficiency in BBSome Component BBS1 Interferes with Selective Immune Responses. Stump M, Guo DF, Rahmouni K. Am J Physiol Regul Integr Comp Physiol. 2022 Dec 19. doi: 10.1152/ajpregu.00243.2022. PMID: 36534590

December 17

Activation of Amygdala Prokineticin receptor 2 neurons drives the anorexigenic activity of the neuropeptide PK2. Yin TC, Mittal A, Buscaglia P, Li W, Sebag JA. J Biol Chem. 2022 Dec 17:102814. doi: 10.1016/j.jbc.2022.102814. PMID: 36539034

December 16

Characterization of Antibodies against Receptor Activity-Modifying Protein 1 (RAMP1): A Cautionary Tale. Hendrikse ER, Rees TA, Tasma Z, Garelja ML, Siow A, Harris PWR, Pawlak JB, Caron KM, Blakeney ES, Russo AF, Sowers LP, Lutz TA, Le Foll C, Walker CS, Hay DL. Int J Mol Sci. 2022 Dec 16;23(24):16035. doi: 10.3390/ijms232416035. PMID: 36555690

December 14

Choroidal Neovascularization is Common in Best Vitelliform Macular Dystrophy and Plays a Role in Vitelliform Lesion Evolution. Han IC, Coussa RG, Mansoor M, Critser DB, Sohn EH, Russell JF, Stone EM. Ophthalmol Retina. 2022 Dec 14:S2468-6530(22)00606-6. doi: 10.1016/j.oret.2022.11.014. PMID: 36528270

December 13

A Proposal to Refer to Four Coronaviruses of Limited Human Virulence "Common Cold Coronaviruses". McIntosh K, Perlman S, Monto A, Englund JA. J Infect Dis. 2022 Dec 13;226(12):2047-2049. doi: 10.1093/infdis/jiac355. PMID: 36052654
Artificially sweetened beverages and urinary incontinence-a secondary analysis of the Women's Health Initiative Observational Study. Ringel NE, Hovey KM, Andrews CA, Mossavar-Rahmani Y, Shadyab AH, Snetselaar LG, Howard BV, Iglesia CB. Menopause. 2022 Dec 13. doi: 10.1097/GME.0000000000002129. PMID: 36515559
Krt14 and Krt15 differentially regulate regenerative properties and differentiation potential of airway basal cells. Ievlev V, Lynch TJ, Freischlag KW, Gries CB, Shah A, Pai AC, Ahlers BA, Park SY, Engelhardt JF, Parekh KR. JCI Insight. 2022 Dec 13:e162041. doi: 10.1172/jci.insight.162041. PMID: 36512409
Stability of Phenyl-Modified Triphenylphosphonium Conjugates and Interactions with DTPA. Gruenwald HK, Kerns RJ. ACS Omega. 2022 Dec 13;7(51):48332-48339. doi: 10.1021/acsomega.2c06525. PMID: 36591157

December 11

Evidence of within-facility patient-patient Clostridiodes difficile infection spread across diverse settings. Justice S, Sewell DK, Li H, Miller AC, Polgreen PM. Epidemiol Infect. 2022 Dec 11:1-23. doi: 10.1017/S0950268822001893. PMID: 36502810

December 10

The BBSome regulates mitochondria dynamics and function. Guo DF, Merrill RA, Qian L, Hsu Y, Zhang Q, Lin Z, Thedens DR, Usachev YM, Grumbach I, Sheffield VC, Strack S, Rahmouni K. Mol Metab. 2022 Dec 10:101654. doi: 10.1016/j.molmet.2022.101654. PMID: 36513220

December 9

Incidence and severity of thrombocytopenia associated with use of intravascular microaxial ventricular assist devices for treatment of cardiogenic shock. Goetz J, O'Brien M, Bream-Rouwenhorst H, Toyoda A, Hobbs R, Horwitz PA. Catheter Cardiovasc Interv. 2022 Dec 9. doi: 10.1002/ccd.30520. PMID: 36490219
Selective androgen receptor modulator microparticle formulation reverses muscle hyperalgesia in a mouse model of widespread muscle pain. Lesnak JB, Nakhla DS, Plumb AN, McMillan A, Saha S, Gupta N, Xu Y, Phruttiwanichakun P, Rasmussen L, Meyerholz DK, Salem AK, Sluka KA. Pain. 2022 Dec 9. doi: 10.1097/j.pain.0000000000002841. PMID: 36508167

December 8

Machine-learning based investigation of prognostic indicators for oncological outcome of pancreatic ductal adenocarcinoma. Chang J, Liu Y, Saey SA, Chang KC, Shrader HR, Steckly KL, Rajput M, Sonka M, Chan CHF. Front Oncol. 2022 Dec 8;12:895515. doi: 10.3389/fonc.2022.895515. PMID: 36568148
Postnatal Leptin Levels Correlate with Breast Milk Leptin Content in Infants Born before 32 Weeks Gestation. Chatmethakul T, Schmelzel ML, Johnson KJ, Walker JR, Santillan DA, Colaizy TT, Roghair RD. Nutrients. 2022 Dec 8;14(24):5224. doi: 10.3390/nu14245224. PMID: 36558383

December 6

Cardiac Adverse Events Associated With Chemo-Radiation Versus Chemotherapy for Resectable Stage III Non-Small-Cell Lung Cancer: A Surveillance, Epidemiology and End Results-Medicare Study. Herbach E, O'Rorke MA, Carnahan RM, McDowell BD, Allen B, Grumbach I, London B, Smith BJ, Spitz DR, Seaman A, Chrischilles EA. J Am Heart Assoc. 2022 Dec 6;11(23):e027288. doi: 10.1161/JAHA.122.027288. PMID: 36453633

December 5

Federated learning enables big data for rare cancer boundary detection. Pati S,…Allen B, Buatti JM,….Bakas S. Nat Commun. 2022 Dec 5;13(1):7346. doi: 10.1038/s41467-022-33407-5. PMID: 36470898
Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. Chheda PR, Nieto N, Kaur S, Beck JM, Beck JR, Honzatko R, Kerns RJ, Nelson SW. Eur J Med Chem. 2022 Dec 5;243:114751. doi: 10.1016/j.ejmech.2022.114751. PMID: 3619140

December 2

Prohibiting MG53 Phosphorylation Optimizes its Therapeutic Potential in Diabetes. Hall DD, Shi Q, Song LS. Circ Res. 2022 Dec 2;131(12):977-979. doi: 10.1161/CIRCRESAHA.122.322132. PMID: 36454851

December 1