Publications

Current Year Publications

November 30

Diagnostic stewardship and dermatology consultation in cellulitis management: a systematic literature review and meta-analysis. Lin V, Callado GY, Pardo I, Gutfreund M, Hsieh MK, Pereira AMR, Kwong BY, Aleshin M, Holubar M, Salinas JL, Diekema DJ, Marra AR. Arch Dermatol Res. 2024 Nov 30;317(1):61. doi: 10.1007/s00403-024-03515-x. PMID: 39614879

November 28

Outcomes of Device Extraction in Patients with Chronic Kidney Disease on Renal Replacement Therapy and Cardiac Implantable Electronic Device Infections. Alzahrani A, Lamont L, Mhanna M, Farjo P, Powers EM, Bailin S, Dominic P. Heart Rhythm. 2024 Nov 28:S1547-5271(24)03636-1. doi: 10.1016/j.hrthm.2024.11.052. PMID: 39615815

November 27

miRNA-6236 Regulation of Postischemic Skeletal Muscle Angiogenesis. Mani AM, Lamin V, Peach RC, Friesen EH, Wong T, Singh MV, Dokun AO. J Am Heart Assoc. 2024 Nov 27:e035923. doi: 10.1161/JAHA.124.035923. PMID: 39604034
Parameter Estimation and Identifiability in Kinetic Flux Profiling Models of Metabolism. Guppy B, Mitchell C, Taylor EB. Bull Math Biol. 2024 Nov 27;87(1):7. doi: 10.1007/s11538-024-01386-x. PMID: 39601930

November 26

Comparison of outcomes by race among a population-based matched sample of multiple myeloma patients. Greteman BB, Tomasson MH, Kahl AR, Wahlen MM, Bates ML, Strouse C, Charlton ME. Cancer Causes Control. 2024 Nov 26. doi: 10.1007/s10552-024-01938-5. PMID: 39586915

November 25

American College of Surgeons survival calculator for biliary tract cancers: using machine learning to individualize predictions. Janczewski LM, Cotler J, Zhu X, Palis B, Chan K, Merkow RP, Habermann EB, Weigel RJ, Boughey JC. Surgery. 2024 Nov 25:108919. doi: 10.1016/j.surg.2024.10.010. PMID: 39592334
Phenotypes and Trajectories of Tobacco-exposed Persons with Preserved Spirometry: Insights from Lung Volumes. Arjomandi M, Zeng S, Barjaktarevic I, Bleecker ER, Bowler RP, Criner GJ, Comellas AP, Couper DJ, Curtis JL, Dransfield MT, Drummond MB, Fortis S, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Kanner RE, Krishnan JA, Labaki W, Ortega VE, Peters SP, Rennard SI, Cooper CB, Tashkin DP, Paine R 3rd, Woodruff PG. Ann Am Thorac Soc. 2024 Nov 25. doi: 10.1513/AnnalsATS.202405-527OC. PMID: 39586032

November 22

Tracking autonomic nervous system activity using surface ECG: Personalized, multiparametric evaluation. Shusterman V, Swenne CA, Hoffman S, Strollo PJ, London B. J Electrocardiol. 2024 Nov 22;88:153837. doi: 10.1016/j.jelectrocard.2024.153837. PMID: 39615267

November 20

De novo missense variants in the PP2A regulatory subunit PPP2R2B in a neurodevelopmental syndrome: potential links to mitochondrial dynamics and spinocerebellar ataxias. Sandal P, Jong CJ, Merrill RA, Kollman GJ, Paden AH, Bend EG, Sullivan J, Spillmann RC, Shashi V, Vulto-van Silfhout AT, Pfundt R, de Vries BBA, Li PP, Bicknell LS, Strack S. Hum Mol Genet. 2024 Nov 20:ddae166. doi: 10.1093/hmg/ddae166. PMID: 39565297
Pregabalin produces analgesia in males but not females in an animal model of chronic widespread muscle pain. Plumb AN, Hayashi K, Janowski A, Smith A, Rasmussen L, Sluka KA, Lesnak JB. Pain Rep. 2024 Nov 20;9(6):e1207. doi: 10.1097/PR9.0000000000001207. PMID: 39574484

November 19

Secondary causal mediation analysis of a pragmatic clinical trial to evaluate the effect of chiropractic care for US active-duty military on biopsychosocial outcomes occurring through effects on low back pain interference and intensity. Shannon ZK, Long CR, Chrischilles E, Goertz C, Wallace R, Casteel C, Carnahan RM. BMJ Open. 2024 Nov 19;14(11):e083509. doi: 10.1136/bmjopen-2023-083509. PMID: 39566948. Clinical Trial.

November 18

A dynamical systems model for the total fission rate in Drp1-dependent mitochondrial fission. Leinheiser AK, Mitchell CC, Rooke E, Strack S, Grueter CE. PLoS Comput Biol. 2024 Nov 18;20(11):e1012596. doi: 10.1371/journal.pcbi.1012596. PMID: 39556606
Effects of Age and Diet on Triglyceride Metabolism in Mice. Spitler KM, Shetty SK, Davies BSJ. J Lipid Res. 2024 Nov 18:100706. doi: 10.1016/j.jlr.2024.100706. PMID: 39566846
Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs. Conway TP, Vu BG, Beattie SR, Krysan DJ, Moye-Rowley WS. mSphere. 2024 Nov 18:e0079224. doi: 10.1128/msphere.00792-24. PMID: 39555934

November 17

Impact of electronic health record updates and changes on the delivery and monitoring of interventions in embedded pragmatic clinical trials. Marsolo KA, Cheville A, Melnick ER, Jarvik JG, Simon GE, Sluka KA, Crofford LJ, Staman KL, Richesson RL, Schlaeger JM, Curtis LH. Contemp Clin Trials. 2024 Nov 17:107744. doi: 10.1016/j.cct.2024.107744. PMID: 39561918

November 15

The Effect of Chronic Altitude Exposure on Chronic Obstructive Pulmonary Disease Outcomes in the SPIROMICS Cohort: An Observational Cohort Study. Suri R, Markovic D, Woo H, Arjomandi M, Barr RG, Bowler RP, Criner G, Curtis JL, Dransfield MT, Drummond MB, Fortis S, Han MK, Hoffman EA, Kaner RJ, Kaufman JD, Krishnan JA, Martinez FJ, Ohar J, Ortega VE, Paine R 3rd, Soler X, Woodruff PG, Hansel NN, Cooper CB, Tashkin DP, Buhr RG, Barjaktarevic IZ. Am J Respir Crit Care Med. 2024 Nov 15;210(10):1210-1218. doi: 10.1164/rccm.202310-1965OC. PMID: 38507607

November 14

4DCT image artifact detection using deep learning. Carrizales JW, Flakus MJ, Fairbourn D, Shao W, Gerard SE, Bayouth JE, Christensen GE, Reinhardt JM. Med Phys. 2024 Nov 14. doi: 10.1002/mp.17513. PMID: 39540716
Saturation mutagenesis-reinforced functional assays for disease-related genes. Ma K, Huang S, Ng KK, Lake NJ, Joseph S, Xu J, Lek A, Ge L, Woodman KG, Koczwara KE, Cohen J, Ho V, O'Connor CL, Brindley MA, Campbell KP, Lek M. Cell. 2024 Nov 14;187(23):6707-6724.e22. doi: 10.1016/j.cell.2024.08.047. PMID: 39326416

November 8

Female specific interactions of serotonin and testosterone in the rostral ventromedial medulla after activity-induced muscle pain. Plumb AN, Lesnak JB, Rasmussen L, Sluka KA. J Pain. 2024 Nov 8:104723. doi: 10.1016/j.jpain.2024.104723. PMID: 39522853

November 7

Association of commission on cancer accreditation with receipt of guideline-concordant care and survival among patients with colon cancer. Chan K, Palis BE, Cotler JH, Janczewski LM, Weigel RJ, Bentrem DJ, Ko CY. World J Surg. 2024 Nov 7. doi: 10.1002/wjs.12391. PMID: 39511628
Integrating an industrial hygienist into the infection prevention and control program. Dains A, Baker S, Kobayashi T, Holley S, Diekema D, Brust K. Infect Control Hosp Epidemiol. 2024 Nov 7:1-2. doi: 10.1017/ice.2024.123. PMID: 39506488

November 4

Additive Effects of Cu-ATSM and Radiation on Survival of Diffuse Intrinsic Pontine Glioma Cells. King SA, Solst SR, Graham CH, Fiore LZ, Rheem R, Tomanek-Chalkley A, Fath MA, Caster JM, Spitz DR, Howard ME. Radiat Res. 2024 Nov 4. doi: 10.1667/RADE-24-00076.1. PMID: 39492578
Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study. Hermann EA, Motahari A, Hoffman EA, Sun Y, Allen N, Angelini ED, Bertoni AG, Bluemke DA, Gerard SE, Guo J, Kaczka DW, Laine A, Michos E, Nagpal P, Pankow JS, Sack CS, Smith B, Stukovsky KH, Watson KE, Wysoczanski A, Barr RG. Thorax. 2024 Nov 4:thorax-2024-222002. doi: 10.1136/thorax-2024-222002. PMID: 39496494
Evaluating machine learning model bias and racial disparities in non-small cell lung cancer using SEER registry data. Trentz C, Engelbart J, Semprini J, Kahl A, Anyimadu E, Buatti J, Casavant T, Charlton M, Canahuate G. Health Care Manag Sci. 2024 Nov 4. doi: 10.1007/s10729-024-09691-6. PMID: 39495385

November 3

A pineal region mass in a 55-year-old female. McConeghey A, Abdullaev Z, Aldape K, Moore SA, Lopes Abath Neto O. Brain Pathol. 2024 Nov 3:e13315. doi: 10.1111/bpa.13315. PMID: 39489486

November 1

October 29

Gallbladder mucoceles in dogs: A novel form of acquired CFTR dysfunction causing localized cystic fibrosis-like disease. Meyerholz DK, Stoltz DA. Am J Physiol Gastrointest Liver Physiol. 2024 Oct 29. doi: 10.1152/ajpgi.00302.2024. PMID: 39470598
The Role of Acid-Sensing Ion Channel 1A (ASIC1A) in the Behavioral and Synaptic Effects of Oxycodone and Other Opioids. Fuller MJ, Andrys NRR, Gupta SC, Ghobbeh A, Kreple CJ, Fan R, Taugher-Hebl RJ, Radley JJ, Lalumiere RT, Wemmie JA. Int J Mol Sci. 2024 Oct 29;25(21):11584. doi: 10.3390/ijms252111584. PMID: 39519136

October 28

Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells. Kulhankova K, Cheng AX, Traore S, Auger M, Pelletier M, Hervault M, Wells KD, Green JA, Byrne A, Nelson B, Sponchiado M, Boosani C, Heffner CS, Snow KJ, Murray SA, Villacreses RA, Rector MV, Gansemer ND, Stoltz DA, Allamargot C, Couture F, Hemez C, Hallée S, Barbeau X, Harvey M, Lauvaux C, Gaillet B, Newby GA, Liu DR, McCray PB Jr, Guay D. Nucleic Acids Res. 2024 Oct 28;52(19):11911-11925. doi: 10.1093/nar/gkae819. PMID: 39315713

October 25

A hierarchical hepatic de novo lipogenesis substrate supply network utilizing pyruvate, acetate, and ketones. Rauckhorst AJ, Sheldon RD, Pape DJ, Ahmed A, Falls-Hubert KC, Merrill RA, Brown RF, Deshmukh K, Vallim TA, Deja S, Burgess SC, Taylor EB. Cell Metab. 2024 Oct 25:S1550-4131(24)00409-1. doi: 10.1016/j.cmet.2024.10.013. PMID: 39471817
SARS-CoV-2 seropositivity among healthcare professionals in a rural state. Wright B, Kang D, Schuette A, Ward MA, Krasowski MD, Scherer AM, Diekema DJ, Cavanaugh J, Herwaldt L. Antimicrob Steward Healthc Epidemiol. 2024 Oct 25;4(1):e190. doi: 10.1017/ash.2024.420. PMID: 39465214

October 24

Automated CT-based Decoupling of the Effects of Airway Narrowing and Wall Thinning on Airway Counts in Chronic Obstructive Pulmonary Disease. Nadeem SA, Zhang X, Nagpal P, Hoffman EA, Chan KS, Comellas AP, Saha PK. Br J Radiol. 2024 Oct 24:tqae211. doi: 10.1093/bjr/tqae211. PMID: 39447037
Patient, facility, and environmental factors associated with obesity treatment in US Veterans. Kamalumpundi V, Smith JK, Robinson KM, Saad Eddin A, Alatoum A, Kasasbeh G, Correia MLG, Vaughan Sarrazin M. Obes Sci Pract. 2024 Oct 24;10(5):e70014. doi: 10.1002/osp4.70014. PMID: 39450266
Radiation-Induced Macrovessel/Microvessel Disease. Abe JI, Allen BG, Beyer AM, Lewandowski D, Mapuskar KA, Subramanian V, Tamplin MR, Grumbach IM. Arterioscler Thromb Vasc Biol. 2024 Oct 24. doi: 10.1161/ATVBAHA.124.319866. PMID: 39445428. Review.

October 18

Liver iron stores and effectors of ferroptosis are dependent on age and sex. Bloomer SA, Wagner BA, Buettner GR, Brown KE. Exp Physiol. 2024 Oct 18. doi: 10.1113/EP092035. PMID: 39422319
Load-Dependent Mechanisms Contribute to Increased Aortic Stiffness Among Women with a History of Preeclampsia: Relation with Cardiovagal Baroreflex Sensitivity. Davis KG, Armstrong MK, Nuckols VR, Smith MN, Pewowaruk R, Gimblet CJ, Santillan DA, Santillan MK, Pierce GL. Am J Physiol Heart Circ Physiol. 2024 Oct 18. doi: 10.1152/ajpheart.00556.2024. PMID: 39423036
Loss of endogenous Nox2-NADPH oxidase does not prevent age-induced platelet activation and arterial thrombosis in mice. Ahmed A, Patil G, Sonkar VK, Jensen M, Streeter J, Dayal S. Res Pract Thromb Haemost. 2024 Oct 18;8(7):102597. doi: 10.1016/j.rpth.2024.102597. PMID: 39582807
Sertraline-Induced 5-HT Dysregulation in Mouse Cardiomyocytes and the Impact on Calcium Handling. Lu Y, Kenkel E, Zimmerman K, Weiss RM, Roghair RD, Haskell SE. Am J Physiol Heart Circ Physiol. 2024 Oct 18. doi: 10.1152/ajpheart.00692.2023. PMID: 39423037

October 16

Ghost vessels in the eye: Cell free choriocapillaris domains in atrophic age-related macular degeneration. Mullins RF, Flamme-Wiese MJ, Navratil EM, Boese EA, Varzavand K, Riker MJ, Wang K, Stone EM, Tucker BA. Exp Eye Res. 2024 Oct 16;248:110128. doi: 10.1016/j.exer.2024.110128. PMID: 39419369
Interplay between cannabinoids and the neuroimmune system in migraine. Zorrilla E, Della Pietra A, Russo AF. J Headache Pain. 2024 Oct 16;25(1):178. doi: 10.1186/s10194-024-01883-3. PMID: 39407099. Review.

October 15

Associations between the incidence of Fuchs' endothelial corneal dystrophy and menopausal hormone therapy use and exposure to endogenous estrogen. Millen AE, Nie J, Yue Y, Andrews CA, Wactawski-Wende J, Wallace RB, Shadyab AH, Patel SP. Maturitas. 2024 Oct 15;191:108132. doi: 10.1016/j.maturitas.2024.108132. PMID: 39522475
CT Radiomics Features Predict Change in Lung Density and Rate of Emphysema Progression. Saha P, Bodduluri S, Nakhmani A, Chaudhary MFA, Amudala Puchakalaya PR, Sthanam V, San Jose Estepar R, Reinhardt JM, Zhang C, Bhatt SP. Ann Am Thorac Soc. 2024 Oct 15. doi: 10.1513/AnnalsATS.202401-009OC. PMID: 39404745
Genomic and Serological Rheumatoid Arthritis Biomarkers, MUC5B Promoter Variant, and Interstitial Lung Abnormalities. Kim JS, Flack KF, Malik V, Manichaikul A, Sakaue S, Luo Y, McGroder CF, Salvatore M, Anderson MR, Hoffman EA, Podolanczuk AJ, Yun JH, McDermott GC, Sparks JA, Putman R, Moll M, Rich SS, Rotter JI, Noth I, Raghu G, Giles JT, Winchester R, Raychaudhuri S, Hunninghake GM, Cho MH, Garcia CK, Barr RG, Bernstein EJ. Ann Am Thorac Soc. 2024 Oct 15. doi: 10.1513/AnnalsATS.202403-238OC. PMID: 39405163
Overnutrition causes insulin resistance and metabolic disorder through increased sympathetic nervous system activity. Sakamoto K, Butera MA, Zhou C, Maurizi G, Chen B, Ling L, Shawkat A, Patlolla L, Thakker K, Calle V, Morgan DA, Rahmouni K, Schwartz GJ, Tahiri A, Buettner C. Cell Metab. 2024 Oct 15:S1550-4131(24)00376-0. doi: 10.1016/j.cmet.2024.09.012. PMID: 39437790
Tissue resident memory T cells contribute to protectionagainst heterologousSARS-CoV-2 challenge. Odle A, Kar M, Verma AK, Sariol A, Meyerholz DK, Suthar MS, Wong LR, Perlman S. JCI Insight. 2024 Oct 15:e184074. doi: 10.1172/jci.insight.184074. PMID: 39405115

October 14

Pathogenic T cells in post-viral lung disease in mice. Perlman S, Sariol A. Nat Immunol. 2024 Oct 14. doi: 10.1038/s41590-024-01983-x. PMID: 39402153
Steering Toward New Horizons: A Vision for the Future of The American Journal of Physiology - Regulatory, Integrative and Comparative Physiology. Rahmouni K. Am J Physiol Regul Integr Comp Physiol. 2024 Oct 14. doi: 10.1152/ajpregu.00252.2024. PMID: 39400578

October 11

Feasibility and assessment of self-reported dietary recalls among newly diagnosed multiple sclerosis: a quasi-experimental pilot study. Saxby SM, Ehlinger MA, Brooks L, Titcomb TJ, Ten Eyck P, Rubenstein LM, Bisht B, Shemirani F, Gill C, Kamholtz J, Snetselaar LG, Wahls TL. Front Nutr. 2024 Oct 11;11:1369700. doi: 10.3389/fnut.2024.1369700. PMID: 39464680
Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells. Monroe TB, Hertzel AV, Dickey DM, Hagen T, Santibanez SV, Berdaweel IA, Halley C, Puchalska P, Anderson EJ, Camell CD, Robbins PD, Bernlohr DA. Aging Cell. 2024 Oct 11:e14367. doi: 10.1111/acel.14367. PMID: 39394673

October 9

AptamerRunner: An accessible aptamer structure prediction and clustering algorithm for visualization of selected aptamers. Ruiz-Ciancio D, Veeramani S, Singh R, Embree E, Ortman C, Thiel KW, Thiel WH. Mol Ther Nucleic Acids. 2024 Oct 9;35(4):102358. doi: 10.1016/j.omtn.2024.102358. PMID: 39507401
Multi-omics inhalation toxicity assessment of urban soil dusts contaminated by multiple legacy sources of lead (Pb).Haque E, Adamcakova-Dodd A, Jing X, Wang H, Jarmusch AK, Thorne PS. J Hazard Mater. 2024 Oct 9;480:136120. doi: 10.1016/j.jhazmat.2024.136120. PMID: 39405708

October 8

Association Between Neuromuscular Blocking Agents and Outcomes of Emergency Tracheal Intubation: A Secondary Analysis of Randomized Trials. DeMasi SC, Self WH, Aggarawal NR, April MD, Andrea L, Barnes CR, Brainard J, Blinder V, Dagan A, Driver B, Doerschug KC, Douglas I, Exline M, Fein DG, Gaillard JP, Gandotra S, Gibbs KW, Ginde AA, Halliday SJ, Han JH, Herbert T, High K, Hughes CG, Khan A, Latimer AJ, Maiga AW, Mitchell SH, Muhs AL, Mohamed A, Moskowitz A, Page DB, Palakshappa JA, Prekker ME, Qian ET, Resnick-Ault D, Rice TW, Russel DW, Schauer SG, Seitz KP, Shapiro NI, Smith LM, Sottile P, Stempek S, Trent SA, Vonderhaar DJ, Walker JE, Wang L, Whitson MR, Casey JD, Semler MW; Pragmatic Critical Care Research Group. Ann Emerg Med. 2024 Oct 8:S0196-0644(24)00962-4. doi: 10.1016/j.annemergmed.2024.08.509. PMID: 39387758
CT strain metrics allow for earlier diagnosis of bronchiolitis obliterans syndrome after hematopoietic cell transplant. Sharifi H, Bertini CD, Alkhunaizi M, Hernandez M, Musa Z, Borges C, Turk I, Bashoura L, Dickey BF, Cheng GS, Yanik G, Galban CJ, Guo HH, Godoy MCB, Reinhardt JM, Hoffman EA, Castro M, Rondon G, Alousi AM, Champlin RE, Shpall EJ, Lu Y, Peterson S, Datta K, Nicolls MR, Hsu J, Sheshadri A. Blood Adv. 2024 Oct 8;8(19):5156-5165. doi: 10.1182/bloodadvances.2024013748. PMID: 39163616

October 5

Effects of 28-day nose-only inhalation of PCB52 (2,2',5,5'-Tetrachlorobiphenyl) on the brain transcriptome. Bullert AJ, Wang H, Linahon MJ, Chimenti MS, Adamcakova-Dodd A, Li X, Dailey ME, Klingelhutz AJ, Ankrum JA, Stevens HE, Thorne PS, Lehmler HJ. Toxicology. 2024 Oct 5;509:153965. doi: 10.1016/j.tox.2024.153965. PMID: 39369937

October 2

A randomized trial of pharmacological ascorbate, gemcitabine, and nab-paclitaxel for metastatic pancreatic cancer. Bodeker KL, Smith BJ, Berg DJ, Chandrasekharan C, Sharif S, Fei N, Vollstedt S, Brown H, Chandler M, Lorack A, McMichael S, Wulfekuhle J, Wagner BA, Buettner GR, Allen BG, Caster JM, Dion B, Kamgar M, Buatti JM, Cullen JJ. Redox Biol. 2024 Oct 2;77:103375. doi: 10.1016/j.redox.2024.103375. PMID: 39369582

October 1

September 30

Exonic splice variant discovery using in vitro models of inherited retinal disease. Mullin NK, Bohrer LR, Anfinson KR, Andorf JL, Mullins RF, Tucker BA, Stone EM. HGG Adv. 2024 Sep 30:100357. doi: 10.1016/j.xhgg.2024.100357. PMID: 39354715

September 27

Identification of blood lipid markers of docetaxel treatment in prostate cancer patients. Finnerty MC, Leach FE 3rd, Zakharia Y, Nepple KG, Bartlett MG, Henry MD, Cummings BS. Sci Rep. 2024 Sep 27;14(1):22069. doi: 10.1038/s41598-024-73074-8. PMID: 39333185

September 26

Airway Tapering in Chronic Obstructive Pulmonary Disease. Bodduluri S, Nakhmani A, Kizhakke Puliyakote AS, Reinhardt JM, Dransfield MT, Bhatt SP. Eur Respir J. 2024 Sep 26:2400191. doi: 10.1183/13993003.00191-2024. PMID: 39326917
Characterization of FGF21 Sites of Production and Signaling in Mice. Sullivan AI, Jensen-Cody SO, Claflin KE, Vorhies KE, Flippo KH, Potthoff MJ. Endocrinology. 2024 Sep 26;165(11):bqae120. doi: 10.1210/endocr/bqae120. PMID: 39253796
METTL23 Variants and Patients With Normal-Tension Glaucoma. Scheetz TE, Tollefson MR, Roos BR, Boese EA, Pouw AE, Stone EM, Schnieders MJ, Fingert JH. JAMA Ophthalmol. 2024 Sep 26:e243829. doi: 10.1001/jamaophthalmol.2024.3829. PMID: 39325437
Structure-guided in vitro evolution of nanobodies targeting new viral variants. Ye G, Bu F, Pan R, Mendoza A, Yang G, Spiller B, Wadzinski BE, Du L, Perlman S, Liu B, Li F. PLoS Pathog. 2024 Sep 26;20(9):e1012600. doi: 10.1371/journal.ppat.1012600. PMID: 39325826

September 25

Survey of the Landscape of Society Practice Guidelines for Genetic Testing of Neurodevelopmental Disorders. Srivastava S, Cole JJ, Cohen JS, Chopra M, Smith HS, Deardorff MA, Pedapati E, Corner B, Anixt JS, Jeste S, Sahin M, Gurnett CA, Campbell CA; Intellectual and Developmental Disabilities Research Center (IDDRC) Workgroup on Advocating for Access to Genomic Testing. Ann Neurol. 2024 Sep 25. doi: 10.1002/ana.27045. PMID: 39319594. Review.

September 24

Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells. Kulhankova K, Cheng AX, Traore S, Auger M, Pelletier M, Hervault M, Wells KD, Green JA, Byrne A, Nelson B, Sponchiado M, Boosani C, Heffner CS, Snow KJ, Murray SA, Villacreses RA, Rector MV, Gansemer ND, Stoltz DA, Allamargot C, Couture F, Hemez C, Hallée S, Barbeau X, Harvey M, Lauvaux C, Gaillet B, Newby GA, Liu DR, McCray PB Jr, Guay D. Nucleic Acids Res. 2024 Sep 24:gkae819. doi: 10.1093/nar/gkae819. PMID: 39315713

September 23

ATF4-dependent and independent mitokine secretion from OPA1 deficient skeletal muscle in mice is sexually dimorphic. Streeter J, Persaud L, Gao J, Deeraj M, Fairman W, Miguel García-Peña L, Marti A, Manika C, Gaddi S, Schickling B, Pereira RO, Abel ED. Front. Endocrinol., 2024 September 23; Volume 15 – 2024 https://doi.org/10.3389/fendo.2024.1325286
Categories of the Patient-Specific Functional Scale Activities in Chronic Neck Pain and Their Relationship to the Neck Disability Index. Van Gorp B, Lesnak J, Fleagle T, Hulshizer K, Nielsen-Wise A, Kestel L, Vance C, Sluka KA. Rehabil Res Pract. 2024 Sep 23;2024:3126892. doi: 10.1155/2024/3126892. eCollection 2024. PMID: 39351169
A prefrontal-periaqueductal gray pathway differentially engages autonomic, hormonal, and behavioral features of the stress coping response. Skog TD, Johnson SB, Hinz DC, Lingg RT, Schulz EN, Luna JT, Beltz TG, Romig-Martin SA, Gantz SC, Xue B, Johnson AK, Radley JJ. J Neurosci. 2024 Sep 23:e0844242024. doi: 10.1523/JNEUROSCI.0844-24.2024. PMID: 39313320

September 22

Association between cardiorespiratory fitness and trend of age-related rise in arterial stiffness in individuals with and without hypertension or diabetes. Jae SY, Lee KH, Kim HJ, Kunutsor SK, Pierce GL, Hui SS, Kang M. Am J Hypertens. 2024 Sep 22:hpae124. doi: 10.1093/ajh/hpae124. PMID: 39306668

September 19

Saturation mutagenesis-reinforced functional assays for disease-related genes. Ma K, Huang S, Ng KK, Lake NJ, Joseph S, Xu J, Lek A, Ge L, Woodman KG, Koczwara KE, Cohen J, Ho V, O'Connor CL, Brindley MA, Campbell KP, Lek M. Cell. 2024 Sep 19:S0092-8674(24)00976-0. doi: 10.1016/j.cell.2024.08.047. PMID: 39326416
Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs. Conway TP, Vu BG, Beattie SR, Krysan DJ, Moye-Rowley WS. bioRxiv [Preprint]. 2024 Sep 19:2024.09.19.613905. doi: 10.1101/2024.09.19.613905. PMID: 39345512
Social Vulnerability and Receipt of Guideline-Concordant Care among Patients with Colorectal Cancer. Chan K, Palis BE, Cotler JH, Janczewski LM, Weigel RJ, Ko CY, Bentrem DJ. J Am Coll Surg. 2024 Sep 19. doi: 10.1097/XCS.0000000000001193. PMID: 39297529

September 18

Harnessing the synergistic potential of TiO₂-CuSe composites for enhanced photocatalytic and antibacterial activities. Kiran A, Riaz A, Ali Z, Maryam R, Ahmad F, Hussain R, Siddiqui NA, Hussain A, Zulfiqar S, Cochran EW. RSC Adv. 2024 Sep 18;14(40):29636-29647. doi: 10.1039/d4ra05194g. PMID: 39297037
Preventing Site-Specific Calpain Proteolysis of Junctophilin-2 Protects Against Stress-Induced Excitation-Contraction Uncoupling and Heart Failure Development. Wang J, Chen B, Shi Q, Ciampa G, Zhao W, Zhang G, Weiss RM, Peng T, Hall DD, Song LS. Circulation. 2024 Sep 18. doi: 10.1161/CIRCULATIONAHA.124.069329. PMID: 39291390

September 17

Mouse hepatitis virus JHMV I protein is required for maximal virulence. Lowery SA, Schuster N, Wong L-YR, Carrillo T Jr, Peters E, Odle A, Sariol A, Cesarz I, Li P, Perlman S. J Virol. 2024 Sep 17;98(9):e0068024. doi: 10.1128/jvi.00680-24. PMID: 39158347
Pan-beta-coronavirus subunit vaccine prevents SARS-CoV-2 Omicron, SARS-CoV, and MERS-CoV challenge. Wang G, Verma AK, Guan X, Bu F, Odle AE, Li F, Liu B, Perlman S, Du L. J Virol. 2024 Sep 17;98(9):e0037624. doi: 10.1128/jvi.00376-24. PMID: 39189731
Progressive inner retinal neurodegeneration in non-proliferative macular telangiectasia type 2. Amram AL, Whitmore SS, Wang C, Clavell C, Lyons LJ, Rusakevich AM, Han I, Folk J, Boldt HC, Stone EM, Russell SR, Lee K, Abramoff M, Wykoff C, Sohn EH. Br J Ophthalmol. 2024 Sep 17:bjo-2023-325115. doi: 10.1136/bjo-2023-325115. PMID: 39288977
Respiratory syncytial virus infection provides protection against severe acute respiratory syndrome coronavirus challenge. Hartwig SM, Odle A, Wong L-YR, Meyerholz DK, Perlman S, Varga SM. J Virol. 2024 Sep 17;98(9):e0066924. doi: 10.1128/jvi.00669-24. PMID: 39194251

September 13

Machine learning with multiple modalities of brain magnetic resonance imaging data to identify the presence of bipolar disorder. Deng LR, Harmata GIS, Barsotti EJ, Williams AJ, Christensen GE, Voss MW, Saleem A, Rivera-Dompenciel AM, Richards JG, Sathyaputri L, Mani M, Abdolmotalleby H, Fiedorowicz JG, Xu J, Shaffer JJ, Wemmie JA, Magnotta VA. J Affect Disord. 2024 Sep 13:S0165-0327(24)01510-6. doi: 10.1016/j.jad.2024.09.025. PMID: 39278469
The mitochondrial dicarboxylate carrier mediates in vivo hepatic gluconeogenesis. Pape DJ, Falls-Hubert KC, Merrill RA, Ahmed A, Qian Q, McGivney GR, Sobieralski P, Rauckhorst AJ, Yang L, Taylor EB. bioRxiv [Preprint]. 2024 Sep 13:2024.09.12.612761. doi: 10.1101/2024.09.12.612761. PMID: 39314408
Pro-efferocytic nanotherapies reduce vascular inflammation without inducing anemia in a large animal model of atherosclerosis. Bamezai S, Zhang Y, Kumari M, Lotfi M, Alsaigh T, Luo L, Kumar GS, Wang F, Ye J, Puri M, Manchanda R, Paluri S, Adkar SS, Kojima Y, Ingelsson A, Bell CF, Lopez NG, Fu C, Choi RB, Miller Z, Barrios L, Walsh S, Ahmad F, Maegdefessel L, Smith BR, Leeper NJ. Nat Commun. 2024 Sep 13;15(1):8034. doi: 10.1038/s41467-024-52005-1. PMID: 39271657

September 11

Deep Learning Estimation of Small Airways Disease from Inspiratory Chest CT is Associated with FEV₁ Decline in COPD. Chaudhary MFA, Awan HA, Gerard SE, Bodduluri S, Comellas AP, Barjaktarevic IZ, Graham Barr R, Cooper CB, Galban CJ, Han MK, Curtis JL, Hansel NN, Krishnan JA, Menchaca MG, Martinez FJ, Ohar J, Vargas Buonfiglio LG, Paine R 3rd, Bhatt SP, Hoffman EA, Reinhardt JM. medRxiv [Preprint]. 2024 Sep 11:2024.09.10.24313079. doi: 10.1101/2024.09.10.24313079. PMID: 39314974
Efficacy of a cysteine protease inhibitor compared with enalapril in murine heart failure models. Aluja D, Delgado-Tomás S, Barrabés JA, Miró-Casas E, Ruiz-Meana M, Rodríguez-Sinovas A, Benito B, Wang J, Song LS, Ferreira-González I, Inserte J. iScience. 2024 Sep 11;27(10):110935. doi: 10.1016/j.isci.2024.110935. PMID: 39381741

September 10

Characterization of FGF21 Sites of Production and Signaling in Mice. Sullivan AI, Jensen-Cody SO, Claflin KE, Vorhies KE, Flippo KH, Potthoff MJ. Endocrinology. 2024 Sep 10:bqae120. doi: 10.1210/endocr/bqae120. PMID: 39253796
Il-13 induces loss of CFTR in ionocytes and reduces airway epithelial fluid absorption. Romano Ibarra GS, Lei L, Yu W, Thurman AL, Gansemer ND, Meyerholz DK, Pezzulo AA, McCray PB, Thornell IM, Stoltz DA. J Clin Invest. 2024 Sep 10:e181995. doi: 10.1172/JCI181995. PMID: 39255033
IRS2 Signaling Protects Against Stress-Induced Arrhythmia by Maintaining Ca²⁺ Homeostasis. Shi Q, Wang J, Malik H, Li X, Streeter J, Sharafuddin J, Weatherford E, Stein D, Itan Y, Chen B, Hall D, Song LS, Abel ED. Circulation. 2024 Sep 10. doi: 10.1161/CIRCULATIONAHA.123.065048. PMID: 39253856
The pH-sensitive translocation of V-ATPase in the small airway of cystic fibrosis pigs. Villacreses R, Thornell IM, Li X, Mather SE, Urbano J, Stoltz DA, Zabner J. Am J Physiol Lung Cell Mol Physiol. 2024 Sep 10. doi: 10.1152/ajplung.00147.2024. PMID: 39254087
Pituitary adenylate cyclase-activating polypeptide signalling as a therapeutic target in migraine. Ashina H, Christensen RH, Hay DL, Pradhan AA, Hoffmann J, Reglodi D, Russo AF, Ashina M. Nat Rev Neurol. 2024 Sep 10. doi: 10.1038/s41582-024-01011-4. PMID: 39256637. Review.

September 9

High ionic strength vector formulations enhance gene transfer to airway epithelia. Cooney AL, Loza LM, Najdawi K, Brommel CM, McCray PB Jr, Sinn PL. Nucleic Acids Res. 2024 Sep 9;52(16):9369-9383. doi: 10.1093/nar/gkae640. PMID: 39077931

September 5

Dual-role epitope on SARS-CoV-2 spike enhances and neutralizes viral entry across different variants. Ye G, Bu F, Pan R, Mendoza A, Saxena D, Zheng J, Perlman S, Liu B, Li F. PLoS Pathog. 2024 Sep 5;20(9):e1012493. doi: 10.1371/journal.ppat.1012493. PMID: 39236072

September 4

Overlapping coactivator function is required for transcriptional activation by the Candida glabrata Pdr1 transcription factor. Conway TP, Simonicova L, Moye-Rowley WS. Genetics. 2024 Sep 4;228(1):iyae115. doi: 10.1093/genetics/iyae115. PMID: 39028831

September 2

TRAF3 regulates STAT6 activation and T helper cell differentiation by modulating the phosphatase PTP1B. Arkee T, Hornick EL, Bishop GA. J Biol Chem. 2024 Sep 2:107737. doi: 10.1016/j.jbc.2024.107737. PMID: 39233229

September 1, 2024

August 30

The epigenetic signatures of opioid addiction and physical dependence are prevented by D-cysteine ethyl ester and betaine. McDonough J, Singhal NK, Getsy PM, Knies K, Knauss ZT, Mueller D, Bates JN, Damron DS, Lewis SJ. Front Pharmacol. 2024 Aug 30;15:1416701. doi: 10.3389/fphar.2024.1416701. PMID: 39281282

August 29

Examining the effect of prescription drug monitoring program integration and mandatory use policies on the distribution of methadone and buprenorphine for opioid use disorder, United States, 2009-2021. Johnson CE, Wehby GL, Chrischilles EA, Arndt S, Carnahan RM. Drug Alcohol Depend. 2024 Aug 29;264:112432. doi: 10.1016/j.drugalcdep.2024.112432. PMID: 39241503

August 28

Local Synthesis of Estradiol in the Rostral Ventromedial Medulla Protects against Widespread Muscle Pain in Male Mice. Plumb AN, Lesnak JB, Kolling LJ, Marcinkiewcz CA, Sluka KA. eNeuro. 2024 Aug 28;11(8):ENEURO.0332-24.2024. doi: 10.1523/ENEURO.0332-24.2024. PMID: 39111835
Respiratory syncytial virus infection provides protection against severe acute respiratory syndrome coronavirus challenge. Hartwig SM, Odle A, Wong L-YR, Meyerholz DK, Perlman S, Varga SM. J Virol. 2024 Aug 28:e0066924. doi: 10.1128/jvi.00669-24. PMID: 39194251

August 27

Pan-beta-coronavirus subunit vaccine prevents SARS-CoV-2 Omicron, SARS-CoV, and MERS-CoV challenge. Wang G, Verma AK, Guan X, Bu F, Odle AE, Li F, Liu B, Perlman S, Du L. J Virol. 2024 Aug 27:e0037624. doi: 10.1128/jvi.00376-24. PMID: 39189731

August 26

The cell-permeant antioxidant D-thiol ester D-cysteine ethyl ester overcomes physical dependence to morphine in male Sprague Dawley rats. Getsy PM, Coffee GA, Bates JN, Parran T, Hoffer L, Baby SM, MacFarlane PM, Knauss ZT, Damron DS, Hsieh YH, Bubier JA, Mueller D, Lewis SJ. Front Pharmacol. 2024 Aug 26;15:1444574. doi:10.3389/fphar.2024.1444574.PMID: 39253377

August 23

Every Crisis Is an Opportunity: Advancing Blood Culture Stewardship During a Blood Culture Bottle Shortage. Ryder JH, Van Schooneveld TC, Diekema DJ, Fabre V. Open Forum Infect Dis. 2024 Aug 23;11(9):ofae479. doi: 10.1093/ofid/ofae479. PMID: 39238843
Radiomics Based Differentiation of Glioblastoma and Metastatic Disease: Impact of Different T1-Contrast Enhanced Sequences on Radiomic Features and Model Performance. Bathla G, Zamboni CG, Larson N, Liu Y, Zhang H, Lee NH, Agarwal AK, Soni N, Sonka M. AJNR Am J Neuroradiol. 2024 Aug 23:ajnr.A8470. doi: 10.3174/ajnr.A8470. PMID: 39179298

August 22

Evaluating the role of sex-related structure-function differences on airway aerosol transport and deposition. Jin G, Kumar H, Clark AR, Burrowes KS, Hoffman EA, Tawhai MH. J Appl Physiol (1985). 2024 Aug 22. doi: 10.1152/japplphysiol.00898.2023. PMID: 39169840
Spectrum of inflammatory manifestations in patients with NOD2 high-risk alleles. Lozano-Chinga MM, Walsh M, Harrison B, Ballas ZK. Ann Allergy Asthma Immunol. 2024 Aug 22:S1081-1206(24)00530-1. doi: 10.1016/j.anai.2024.08.017. PMID: 39181392

August 21

Development and Initial Characterization of Pigs with DNAI1 Mutations and Primary Ciliary Dyskinesia. Abou Alaiwa MA, Hilkin BM, Price MP, Gansemer ND, Rector MR, Stroik MR, Powers LS, Whitworth KM, Samuel MS, Jain A, Ostedgaard LS, Ernst SE, Philibert W, Boyken LD, Moninger TO, Karp PH, Hornick DB, Sinn PL, Fischer AJ, Pezzulo AA, McCray PB Jr, Meyerholz DK, Zabner J, Prather RS, Welsh MJ, Stoltz DA. bioRxiv [Preprint]. 2024 Aug 21:2024.05.22.594822. doi: 10.1101/2024.05.22.594822. PMID: 39229081
Muscle-derived IL-1β regulates EcSOD expression via the NBR1-p62-Nrf2 pathway in muscle during cancer cachexia. Yamada M, Warabi E, Oishi H, Lira VA, Okutsu M. J Physiol. 2024 Aug 21. doi: 10.1113/JP286460. PMID: 39167700

August 20

CT strain metrics allow for earlier diagnosis of bronchiolitis obliterans syndrome after hematopoietic cell transplant. Sharifi H, Bertini CD, Alkhunaizi M, Hernandez MP, Musa Z, Borges C, Turk I, Bashoura L, Dickey BF, Cheng GS, Yanik GA, Galban C, Guo HH, Godoy M, Reinhardt J, Hoffman E, Castro M, Rondon G, Alousi A, Champlin RE, Shpall EJ, Lu Y, Peterson SW, Datta K, Nicolls M, Hsu JL, Sheshadri A. Blood Adv. 2024 Aug 20:bloodadvances.2024013748. doi: 10.1182/bloodadvances.2024013748. PMID: 39163616

August 19

Mouse hepatitis virus JHMV I protein is required for maximal virulence. Lowery SA, Schuster N, Wong L-YR, Carrillo T Jr, Peters E, Odle A, Sariol A, Cesarz I, Li P, Perlman S. J Virol. 2024 Aug 19:e0068024. doi: 10.1128/jvi.00680-24. PMID: 39158347

August 16

Design of the SPIROMICS Study of Early COPD Progression: SOURCE Study. Curtis JL, Bateman LA, Murray S, Couper DJ, Labaki WW, Freeman CM, Arnold KB, Christenson SA, Alexis NE, Kesimer M, Boucher RC, Kaner RJ, Barjaktarevic I, Cooper CB, Hoffman EA, Barr RG, Bleecker ER, Bowler RP, Comellas A, Dransfield MT, Freedman MB, Hansel NN, Krishnan JA, Marchetti N, Meyers DA, Ohar J, O'Neal WK, Ortega VE, Paine Iii R, Peters SP, Smith BM, Wedzicha JA, Wells JM, Woodruff PG, Han MK, Martinez FJ. Chronic Obstr Pulm Dis. 2024 Aug 16. doi: 10.15326/jcopdf.2023.0490. PMID: 39159077
The headache research priorities: Research goals from the American Headache Society and an international multistakeholder expert group. Schwedt TJ, Pradhan AA, Oshinsky ML, Brin MF, Rosen H, Lalvani N, Charles A, Ashina M, Do TP, Burstein R, Gelfand AA, Dodick DW, Pozo-Rosich P, Lipton RB, Ailani J, Szperka CL, Charleston L 4th, Digre KB, Russo AF, Buse DC, Powers SW, Tassorelli C, Goadsby PJ; Headache Research Priorities Working Group Members. Headache. 2024 Aug 16. doi: 10.1111/head.14797. PMID: 39149968

August 15

Minimal phenotypes in transgenic mice with the human LOXL1/LOXL1-AS1 locus associated with exfoliation glaucoma. Meyer KJ, Mercer HE, Roos BR, Fingert JH, Anderson MG. Vision Res. 2024 Aug 15;223:108464. doi: 10.1016/j.visres.2024.108464. PMID: 39151208

August 14

Identification of In Vivo Internalizing Cardiac-Specific RNA Aptamers. Narayan C, Lin LH, Barros MN, Gilbert TC, Brown CR, Reddin D, London B, Chen Y, Wilson ME, Streeter J, Thiel WH. bioRxiv [Preprint]. 2024 Aug 14:2024.08.13.607054. doi: 10.1101/2024.08.13.607054. PMID: 39185150
Mechanical ventilation guided by driving pressure optimizes local pulmonary biomechanics in an ovine model. Lagier D, Zeng C, Kaczka DW, Zhu M, Grogg K, Gerard SE, Reinhardt JM, Ribeiro GCM, Rashid A, Winkler T, Vidal Melo MF. Sci Transl Med. 2024 Aug 14;16(760):eado1097. doi: 10.1126/scitranslmed.ado1097. PMID: 39141699

August 13

Challenging the role of a NOX4-Piezo1 axis in neutrophil bactericidal function. Knaus UG, Clark RA, Nauseef WM, Dinauer MC, Leto TL, Jaquet V. Immunity. 2024 Aug 13;57(8):1716-1718. doi: 10.1016/j.immuni.2024.07.012.PMID: 39142268
MIRO1 controls energy production and proliferation of smooth muscle cells. Qian L, Koval OM, Endoni BT, Juhr D, Stein CS, Allamargot C, Lin LH, Guo DF, Rahmouni K, Boudreau RL, Streeter J, Thiel WH, Grumbach IM. bioRxiv [Preprint]. 2024 Aug 13:2024.08.13.607854. doi: 10.1101/2024.08.13.607854. PMID: 39185180
A Novel Artificial Intelligence-based Parameterization Approach of the Stromal Landscape in Merkel Cell Carcinoma: a Multi-Institutional Study. Bui CM, Le MK, Kawai M, Vuong HG, Rybski KJ, Mannava K, Kondo T, Okamoto T, Laageide L, Swick B, Balzer B, Smoller BR. Lab Invest. 2024 Aug 13:102123. doi: 10.1016/j.labinv.2024.102123. PMID: 39147033

August 10

microRNA-1 Regulates Metabolic Flexibility in Skeletal Muscle via Pyruvate Metabolism. Ismaeel A, Peck BD, Montgomery MM, Burke BI, Goh J, Kang G, Franco AB, Xia Q, Goljanek-Whysall K, McDonagh B, McLendon JM, Koopmans PJ, Jacko D, Schaaf K, Bloch W, Gehlert S, Wen Y, Murach KA, Peterson CA, Boudreau RL, Fisher-Wellman KH, McCarthy JJ. bioRxiv [Preprint]. 2024 Aug 10:2024.08.09.607377. doi: 10.1101/2024.08.09.607377. PMID: 3914934

August 8

Mutant Huntingtin Drives Development of an Advantageous Brain Early in Life: Evidence in Support of Antagonistic Pleiotropy. Neema M, Schultz JL, Langbehn DR, Conrad AL, Epping EA, Magnotta VA, Nopoulos PC. Ann Neurol. 2024 Aug 8. doi: 10.1002/ana.27046. PMID: 39115048
A reciprocal relationship between mitochondria and lipid peroxidation determines the chondrocyte intracellular redox environment. Hines MR, Gomez-Contreras PC, Liman S, Wilson AM, Lu KJ, O'Neill JA, Fisher JS, Fredericks DC, Wagner BA, Buettner GR, Van Remmen H, Coleman MC. Redox Biol. 2024 Aug 8;75:103306. doi: 10.1016/j.redox.2024.103306. PMID: 39133964

August 7

Astrocyte Mitochondria Are a Sensitive Target of PCB52 and its Human-Relevant Metabolites. Paranjape N, Strack S, Lehmler HJ, Doorn JA. ACS Chem Neurosci. 2024 Aug 7;15(15):2729-2740. doi: 10.1021/acschemneuro.4c00116. PMID: 38953493
Hospitalizations among family members increase the risk of MRSA infection in a household. Miller AC, Arakkal AT, Sewell DK, Segre AM, Adhikari B, Polgreen PM; CDC MInD-Healthcare Group. Infect Control Hosp Epidemiol. 2024 Aug 7:1-7. doi: 10.1017/ice.2024.106. PMID: 39106984
Local synthesis of estradiol in the rostral ventromedial medulla protects against widespread muscle pain in male mice. Plumb AN, Lesnak JB, Kolling LJ, Marcinkiewcz CA, Sluka KA. eNeuro. 2024 Aug 7:ENEURO.0332-24.2024. doi: 10.1523/ENEURO.0332-24.2024. PMID: 39111835

August 6

ANGPTL4 suppresses clear cell renal cell carcinoma via inhibition of lysosomal acid lipase. Jin Z, De U, Tithi TI, Kleberg J, Nataraj A, Jolley E, Carelock ME, Davies BS, Zhang W, Kolb R. Cancer Res Commun. 2024 Aug 6. doi: 10.1158/2767-9764.CRC-24-0016. PMID: 39105498
Demonstration of the pathogenicity of a common non-exomic mutation in ABCA4 using iPSC-derived retinal organoids and retrospective clinical data. Burnight ER, Fenner BJ, Han IC, DeLuca AP, Whitmore SS, Bohrer LR, Andorf JL, Sohn EH, Mullins RF, Tucker BA, Stone EM. Hum Mol Genet. 2024 Aug 6;33(16):1379-1390. doi: 10.1093/hmg/ddad176. PMID: 37930186
The highly metastatic 4T1 breast carcinoma model possesses features of a hybrid epithelial-mesenchymal phenotype. Herndon ME, Ayers M, Gibson-Corley K, Wendt MK, Wallrath LL, Henry MD, Stipp CS. Dis Model Mech. 2024 Aug 6:dmm.050771. doi: 10.1242/dmm.050771. PMID: 39104192
Mucociliary Clearance is Impaired in Small Airways of Cystic Fibrosis Pigs. Stewart CG, Hilkin BM, Gansemer ND, Adam RJ, Dick DW, Sunderland JJ, Stoltz DA, Zabner J, Abou Alaiwa MH. Am J Physiol Lung Cell Mol Physiol. 2024 Aug 6. doi: 10.1152/ajplung.00010.2024. PMID: 39104314
A Patch Wearable Cardioverter-Defibrillator for Patients at Risk of Sudden Cardiac Arrest. Hummel J, Houmsse M, Tomassoni G, Nair D, Romero J, Hargrove J, Mathews K, Thakkar AB, Ullery S, Eapen ZJ, Kumar UN, Mehran R, Butler J; Jewel IDE Study Investigators. J Am Coll Cardiol. 2024 Aug 6;84(6):525-536. doi: 10.1016/j.jacc.2024.04.063. PMID: 39084827
Structural basis for mouse receptor recognition by bat SARS2-like coronaviruses. Zhang W, Shi K, Hsueh FC, Mendoza A, Ye G, Huang L, Perlman S, Aihara H, Li F. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2322600121. doi: 10.1073/pnas.2322600121. PMID: 39083418

August 5

An Approach to Successful Development of Clinician-Scientists in Neurology: The NINDS R25 Experience. Josephson SA, Tennekoon MS, Carmichael ST, Cash SS, Detre JA, Hillis AE, Pennell PB, Pomeroy SL, Richerson GB, Sansing LH, Korn SJ. Ann Neurol. 2024 Aug 5. doi: 10.1002/ana.27050. PMID: 39099460

August 4

Joint effect of rheumatoid arthritis and diet quality on cardiovascular and mortality outcomes: insights from the Women's Health Initiative. Malani K, Pradhan S, Roberts M, Saquib N, Snetselaar L, Shadyab A, Eaton CB. Clin Rheumatol. 2024 Aug 4. doi: 10.1007/s10067-024-07092-2. PMID: 39098912

August 2

Urine dipstick blood and acute kidney injury in infants undergoing cardiopulmonary bypass. Strong AE, Zee J, Laskin BL, Howarth K, Blinder J, Chrischilles EA, Erez DL, Denburg MR. Pediatr Nephrol. 2024 Aug 2. doi: 10.1007/s00467-024-06464-9. PMID: 39093456

August 1

July 31

Exercise effects on brain health and learning from minutes to months: The brain EXTEND trial. Voss MW, Oehler C, Daniels W, Sodoma M, Madero B, Kent J, Jain S, Jung M, Nuckols VR, DuBose LE, Davis KG, O'Deen A, Hamilton C, Baller K, Springer J, Rivera-Dompenciel A, Pipoly M, Muellerleile M, Nagarajan N, Bjarnason T, Harb N, Lin LC, Magnotta V, Hazeltine E, Long JD, Pierce GL. Contemp Clin Trials. 2024 Jul 31:107647. doi: 10.1016/j.cct.2024.107647. PMID: 39095013
A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria. Faniyan TS, Zhang X, Morgan DA, Robles J, Bathina S, Brookes PS, Rahmouni K, Perry RJ, Chhabra KH. Elife. 2024 Jul 31;12:RP91540. doi: 10.7554/eLife.91540. PMID: 39082939

July 30

Gene-specific transcriptional activation by the Aspergillus fumigatus AtrR factor requires a conserved C-terminal domain. Ror S, Stamnes MA, Moye-Rowley WS. mSphere. 2024 Jul 30;9(7):e0042524. doi: 10.1128/msphere.00425-24. PMID: 3897576
High ionic strength vector formulations enhance gene transfer to airway epithelia. Cooney AL, Loza LM, Najdawi K, Brommel CM, McCray PB Jr, Sinn PL. Nucleic Acids Res. 2024 Jul 30:gkae640. doi: 10.1093/nar/gkae640. PMID: 39077931

July 25

Eosinophil expression of triggering receptor expressed on myeloid cells 1 (TREM-1) restricts type 2 lung inflammation. Bowen JL, Keck K, Baruah S, Nguyen KH, Thurman AL, Pezzulo AA, Klesney-Tait J. J Leukoc Biol. 2024 Jul 25;116(2):409-423. doi: 10.1093/jleuko/qiae061. PMID: 38547428
TRAF3 regulation of proximal TLR signaling in B cells. Ybarra TK, Bishop GA. J Leukoc Biol. 2024 Jul 25;116(2):210-223. doi: 10.1093/jleuko/qiae038. PMID: 38489541
Universal subunit vaccine protects against multiple SARS-CoV-2 variants and SARS-CoV. Wang G, Verma AK, Shi J, Guan X, Meyerholz DK, Bu F, Wen W, Liu B, Li F, Perlman S, Du L. NPJ Vaccines. 2024 Jul 25;9(1):133. doi: 10.1038/s41541-024-00922-z. PMID: 39054338
Upregulation of Fatty Acid Synthesis Genes in the Livers of Adolescent Female Rats Caused by Inhalation Exposure to PCB52 (2,2',5,5'-Tetrachlorobiphenyl). Helm-Kwasny BK, Bullert A, Wang H, Chimenti MS, Adamcakova-Dodd A, Jing X, Li X, Meyerholz DK, Thorne PS, Lehmler HJ, Ankrum JA, Klingelhutz AJ. Environ Toxicol Pharmacol. 2024 Jul 25:104520. doi: 10.1016/j.etap.2024.104520. PMID: 39067718

July 24

A Light-Responsive Neural Circuit Suppresses Feeding. Liu H, Qu N, Gonzalez NV, Palma MA, Chen H, Xiong J, Choubey A, Li Y, Li X, Yu M, Liu H, Tu L, Zhang N, Yin N, Conde KM, Wang M, Bean JC, Han J, Scarcelli NA, Yang Y, Saito K, Cui H, Tong Q, Sun Z, Wang C, Cai X, Lu L, He Y, Xu Y. J Neurosci. 2024 Jul 24;44(30):e2192232024. doi: 10.1523/JNEUROSCI.2192-23.2024. PMID: 38897723
SOX6 expression and aneurysms of the thoracic and abdominal aorta. Carmona-Berrio D, Adarve-Rengifo I, Marshall AG, Vue Z, Hall DD, Miller-Fleming TW, Actkins KV, Beasley HK, Almonacid PM, Barturen-Larrea P, Wells QS, Lopez MG, Garza-Lopez E, Dai DF, Shao J, Neikirk K, Billings FT 4th, Curci JA, Cox NJ, Gama V, Hinton A Jr, Gomez JA. iScience. 2024 Jul 24;27(9):110436. doi: 10.1016/j.isci.2024.110436. PMID: 39262802

July 23

Mutations in nonstructural proteins essential for pathogenicity in SARS-CoV-2-infected mice. Pan R, Li P, Meyerholz DK, Perlman S. J Virol. 2024 Jul 23;98(7):e0058424. doi: 10.1128/jvi.00584-24. PMID: 38888344
Ultra-low dose hip CT-based automated measurement of volumetric bone mineral density at proximal femoral subregions. Zhang X, Nadeem SA, DiCamillo PA, Shibli-Rahhal A, Regan EA, Barr RG, Hoffman EA, Comellas AP, Saha PK. Med Phys. 2024 Jul 23. doi: 10.1002/mp.17319. PMID: 39042053

July 20

"Where are they now?" Catching up with the 2019 AAAAI Faculty Development Awardees. Ballas ZK. J Allergy Clin Immunol. 2024 Jul 20:S0091-6749(24)00735-8. doi: 10.1016/j.jaci.2024.07.007. PMID: 39038587

July 19

Overlapping coactivator function is required for transcriptional activation by the Candida glabrata Pdr1 transcription factor. Conway TP, Simonicova L, Moye-Rowley WS. Genetics. 2024 Jul 19:iyae115. doi: 10.1093/genetics/iyae115. PMID: 39028831

July 17

The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors. Dravillas CE, Coleman SS, Hoyd R, Caryotakis G, Denko L, Chan CHF, Churchman ML, Denko N, Dodd RD, Eljilany I, Hardikar S, Husain M, Ikeguchi AP, Jin N, Ma Q, McCarter MD, Osman AEG, Robinson LA, Singer EA, Tinoco G, Ulrich CM, Zakharia Y, Spakowicz D, Tarhini AA, Tan AC. Cancer Res Commun. 2024 Jul 17. doi: 10.1158/2767-9764.CRC-23-0170. PMID: 39015091

July 16

Association of Diet Quality with Risk of Incident Rheumatoid Arthritis in the Women's Health Initiative. Malani K, Pradhan S, Madani MM, Roberts MB, Shadyab A, Allison M, Brasky TM, Schnatz PF, Snetselaar L, Eaton CB. J Acad Nutr Diet. 2024 Jul 16:S2212-2672(24)00553-7. doi: 10.1016/j.jand.2024.07.009. PMID: 39025233
A balance between innovation and biosafety. Perlman S. Proc Natl Acad Sci U S A. 2024 Jul 16;121(29):e2410451121. doi: 10.1073/pnas.2410451121. PMID: 38976743

July 15

Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in Chronic Obstructive Pulmonary Disease. Opron K, Begley LA, Erb-Downward JR, Li G, Alexis NE, Barjaktarevic I, Barr RG, Bleecker ER, Boucher R, Bowler RP, Christenson SA, Comellas AP, Criner G, Cooper CB, Couper D, Galban CJ, Han MK, Hastie A, Hatt C, Hoffman EA, Kaner RJ, Kesimer M, Krishnan JA, LaFon DC, Martinez FJ, Ortega VE, Peters SP, Paine R 3rd, Putcha N, Woodruff PG, Huffnagle GB, Kozik AJ, Curtis JL, Huang YJ; SPIROMICS Investigators. Am J Respir Crit Care Med. 2024 Jul 15;210(2):186-200. doi: 10.1164/rccm.202303-0489OC. PMID: 38261629

July 14

Association between renin-angiotensin antagonism and COVID-19-related mortality in patients with essential hypertension: A single center, retrospective cohort study. Kamalumpundi V, Kawasaki S, Cheng L, Meyers EE, Shams E, Ofori O, Eddin A, Correia MLG. J Clin Hypertens (Greenwich). 2024 Jul 14. doi: 10.1111/jch.14869. PMID: 39003579

July 13

Pathogen-Agnostic Advanced Molecular Diagnostic Testing for Difficult-to-Diagnose Clinical Syndromes-Results of an Emerging Infections Network Survey of Frontline US Infectious Disease Clinicians, May 2023. Rao PS, Downie DL, David-Ferdon C, Beekmann SE, Santibanez S, Polgreen PM, Kuehnert M, Courtney S, Lee JS, Chaitram J, Salerno RM, Gundlapalli AV. Open Forum Infect Dis. 2024 Jul 13;11(8):ofae395. doi: 10.1093/ofid/ofae395. PMID: 39113826

July 12

A confusion of pathways: Discerning cell death mechanisms in SARS-CoV-2 infection. Wong LR, Perlman S. Sci Immunol. 2024 Jul 12;9(97):eadp8170. doi: 10.1126/sciimmunol.adp8170. PMID: 38996011. Review.
An MITF- and mTOR-dependent FLCN pathway suppresses TFE3-driven metastasis in melanoma. Chang J, Campbell-Hanson KR, Vanneste M, Yevdash J, Bartschat NI, Jiang J, Bhinu A, Helverson A, Henry MD, Steingrímsson E, Weigel RJ, Cornell RA, Kenny C. bioRxiv [Preprint]. 2024 Jul 12:2024.07.11.603140. doi: 10.1101/2024.07.11.603140. PMID: 39026725

July 11

An Improved Postprocessing Method to Mitigate the Macroscopic Cross-Slice B₀ Field Effect on R2* Measurements in the Mouse Brain at 7T. Lee CY, Thedens DR, Lullmann O, Steinbach EJ, Tamplin MR, Petronek MS, Grumbach IM, Allen BG, Harshman LA, Magnotta VA. Tomography. 2024 Jul 11;10(7):1074-1088. doi: 10.3390/tomography10070081. PMID: 39058053
Parameter Estimation and Identifiability in Kinetic Flux Profiling Models of Metabolism. Guppy B, Mitchell C, Taylor EB. ArXiv [Preprint]. 2024 Jul 11:arXiv:2407.08844v1. PMID: 39040651

July 10

Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells. Sousa AA, Hemez C, Lei L, Traore S, Kulhankova K, Newby GA, Doman JL, Oye K, Pandey S, Karp PH, McCray PB Jr, Liu DR. Nat Biomed Eng. 2024 Jul 10. doi: 10.1038/s41551-024-01233-3. PMID: 38987629

July 9

Corrigendum: Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors. Paudel SN, Hutzen BJ, Miller KE, Garfinkle EAR, Chen CY, Wang PY, Glaspell AM, Currier MA, Ringwalt EM, Boon L, Mardis ER, Cairo MS, Ratner N, Dodd RD, Cassady KA, Cripe TP. Front Immunol. 2024 Jul 9;15:1456897. doi: 10.3389/fimmu.2024.1456897. PMID: 39044814
Incidence and Types of Cardiac Arrhythmias in the Peri-Ictal Period in Patients Having a Generalized Convulsive Seizure. Vilella L, Miyake CY, Chaitanya G, Hampson JP, Omidi SJ, Ochoa-Urrea M, Talavera B, Mancera O, Hupp NJ, Hampson JS, Rani MRS, Lacuey N, Tao S, Sainju RK, Friedman D, Nei M, Scott CA, Gehlbach B, Schuele SU, Ogren JA, Harper RM, Diehl B, Bateman LM, Devinsky O, Richerson GB, Zhang GQ, Lhatoo SD. Neurology. 2024 Jul 9;103(1):e209501. doi: 10.1212/WNL.0000000000209501. PMID: 38870452

July 8

Gene-specific transcriptional activation by the Aspergillus fumigatus AtrR factor requires a conserved C-terminal domain. Ror S, Stamnes MA, Moye-Rowley WS. mSphere. 2024 Jul 8:e0042524. doi: 10.1128/msphere.00425-24. PMID: 38975761

July 5

Achievement of LDL-C <55 mg/dL among US Adults : Findings from the cvMOBIUS2 Registry. Navar AM, Shah NP, Shrader P, Thomas LE, Ahmad Z, Allred C, Chamberlain AM, Chrischilles EA, Dhalwani N, Effron MB, Hayek S, Jones LK, Kalich B, Shapiro MD, Wójcik C, Peterson ED. Am Heart J. 2024 Jul 5:S0002-8703(24)00165-0. doi: 10.1016/j.ahj.2024.06.012. PMID: 38972336
A new path to migraine. Russo AF, Iliff JJ. Science. 2024 Jul 5;385(6704):28-29. doi: 10.1126/science.adq3498. PMID: 38963860

July 4

IL-13 decreases susceptibility to airway epithelial SARS-CoV-2 infection but increases disease severity in vivo. Ghimire S, Xue B, Li K, Gannon RM, Wohlford-Lenane CL, Thurman AL, Gong H, Necker GC, Zheng J, Meyerholz DK, Perlman S, McCray PB Jr, Pezzulo AA. bioRxiv [Preprint]. 2024 Jul 4:2024.07.03.601941. doi: 10.1101/2024.07.03.601941. PMID: 39005257

July 3

Preventive Service Usage and New Chronic Disease Diagnoses: Using PCORnet Data to Identify Emerging Trends, United States, 2018-2022. Jackson SL, Lekiachvili A, Block JP, Richards TB, Nagavedu K, Draper CC, Koyama AK, Womack LS, Carton TW, Mayer KH, Rasmussen SA, Trick WE, Chrischilles EA, Weiner MG, Podila PSB, Boehmer TK, Wiltz JL; PCORnet Network Partners. Prev Chronic Dis. 2024 Jul 3;21:E49. doi: 10.5888/pcd21.230415. PMID: 38959375

July 2

Astrocyte Mitochondria Are a Sensitive Target of PCB52 and its Human-Relevant Metabolites. Paranjape N, Strack S, Lehmler HJ, Doorn JA. ACS Chem Neurosci. 2024 Jul 2. doi: 10.1021/acschemneuro.4c00116. PMID: 38953493
Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression. Qian Q, Li M, Zhang Z, Davis SW, Rahmouni K, Norris AW, Cao H, Ding WX, Hotamisligil GS, Yang L. Cell Metab. 2024 Jul 2;36(7):1550-1565.e9. doi: 10.1016/j.cmet.2024.04.014. PMID: 38718793
Short-Term Statin Treatment Reduces, and Long-Term Statin Treatment Abolishes, Chronic Vascular Injury by Radiation Therapy. Ait-Aissa K, Guo X, Klemmensen M, Juhr D, Leng LN, Koval OM, Grumbach IM. J Am Heart Assoc. 2024 Jul 2;13(13):e033558. doi: 10.1161/JAHA.123.033558. PMID: 38904226
A Survey of Infection Prevention and Animal Assisted Activity Policies in Healthcare Facilities - United States, 2023. Ben-Aderet MA, Louis S, Grein JD, Beekmann SE, Polgreen PM, Uslan DZ. Am J Infect Control. 2024 Jul 2:S0196-6553(24)00583-2. doi: 10.1016/j.ajic.2024.06.024. PMID: 38964660

July 1

June 27

Dysanapsis Genetic Risk Predicts Lung Function Across the Lifespan. Debban CL, Ambalavanan A, Ghosh A, Li Z, Buschur KL, Ma Y, George E, Pistenmaa C, Bertoni AG, Oelsner EC, Michos ED, Moraes TJ, Jacobs DR Jr, Christenson S, Bhatt SP, Kaner RJ, Simons E, Turvey SE, Vameghestahbanati M, Engert JC, Kirby M, Bourbeau J, Tan WC, Gabriel SB, Gupta N, Woodruff PG, Subbarao P, Ortega VE, Bleecker ER, Meyers DA, Rich SS, Hoffman EA, Barr RG, Cho MH, Bossé Y, Duan Q, Manichaikul A, Smith BM. Am J Respir Crit Care Med. 2024 Jun 27. doi: 10.1164/rccm.202401-0011OC. PMID: 38935874
Increased Muc5AC and Decreased Ciliated Cells in Severe Asthma Partially Restored by Inhibition of IL-4Rα Receptor. Boomer J, Choi J, Alsup A, McGregor MC, Lieu J, Johnson C, Hall C, Shi X, Kim T, Goss C, Lew D, Christenson S, Woodruff PG, Hastie A, Mauger D, Wenzel SE, Hoffman EA, Schechtman KB, Castro M. Am J Respir Crit Care Med. 2024 Jun 27. doi: 10.1164/rccm.202307-1266OC. PMID: 38935626
Systematic data quality assessment of electronic health record data to evaluate study-specific fitness: Report from the PRESERVE research study. Razzaghi H, Goodwin Davies A, Boss S, Bunnell HT, Chen Y, Chrischilles EA, Dickinson K, Hanauer D, Huang Y, Ilunga KTS, Katsoufis C, Lehmann H, Lemas DJ, Matthews K, Mendonca EA, Morse K, Ranade D, Rosenman M, Taylor B, Walters K, Denburg MR, Forrest CB, Bailey LC. PLOS Digit Health. 2024 Jun 27;3(6):e0000527. doi: 10.1371/journal.pdig.0000527. PMID: 38935590
White-opaque switching in Candida albicans: cell biology, regulation, and function. Soll DR. Microbiol Mol Biol Rev. 2024 Jun 27;88(2):e0004322. doi: 10.1128/mmbr.00043-22. PMID: 38546228. Review.

June 26

Changes in the Proteome of the Circle of Willis during Aging Reveal Signatures of Vascular Disease. Subramanian V, Juhr D, Johnson LS, Yem JB, Giansanti P, Grumbach IM. Oxid Med Cell Longev. 2024 Jun 26;2024:4887877. doi: 10.1155/2024/4887877. PMID: 38962180

June 25

Analyzing the relative importance of habitat quantity and quality for boosting pollinator populations in agricultural landscapes. Fijen TPM, Bishop GA, Ganuza C, Scheper J, Kleijn D. Conserv Biol. 2024 Jun 25:e14317. doi: 10.1111/cobi.14317. PMID: 38923557
For the Love of the Game: Calculating the Premium Associated with Academic Surgical Practice. Grimsley EA, Anderson DO, Kendall MA, Zander T, Parikh R, Weigel RJ, Kuo PC. Ann Surg. 2024 Jun 25. doi: 10.1097/SLA.0000000000006414. PMID: 38916098
Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors. Paudel SN, Hutzen BJ, Miller KE, Garfinkle EAR, Chen CY, Wang PY, Glaspell AM, Currier MA, Ringwalt EM, Boon L, Mardis ER, Cairo MS, Ratner N, Dodd RD, Cassady KA, Cripe TP. Front Immunol. 2024 Jun 25;15:1384623. doi: 10.3389/fimmu.2024.1384623. PMID: 39044819

June 24

Brain-derived neurotrophic factor contributes to activity-induced muscle pain in male but not female mice. Hayashi K, Lesnak JB, Plumb AN, Janowski AJ, Smith AF, Hill JK, Sluka KA. Brain Behav Immun. 2024 Jun 24:S0889-1591(24)00459-8. doi: 10.1016/j.bbi.2024.06.019. PMID: 38925417
Tropine exacerbates the ventilatory depressant actions of fentanyl in freely-moving rats. Getsy PM, May WJ, Young AP, Baby SM, Coffee GA, Bates JN, Hsieh YH, Lewis SJ. Front Pharmacol. 2024 Jun 24;15:1405461. doi: 10.3389/fphar.2024.1405461. PMID: 38978984

June 21

Short-Term Statin Treatment Reduces, and Long-Term Statin Treatment Abolishes, Chronic Vascular Injury by Radiation Therapy. Ait-Aissa K, Guo X, Klemmensen M, Juhr D, Leng LN, Koval OM, Grumbach IM. J Am Heart Assoc. 2024 Jun 21:e033558. doi: 10.1161/JAHA.123.033558. PMID: 38904226
State-level factors associated with implementation of prescription drug monitoring program integration and mandatory use policies, United States, 2009-2020. Johnson CE, Chrischilles EA, Arndt S, Carnahan RM. J Am Med Inform Assoc. 2024 Jun 21:ocae160. doi: 10.1093/jamia/ocae160. PMID: 38905012
The tumor microbiome reacts to hypoxia and can influence response to radiation treatment in colorectal cancer. Benej M, Hoyd R, Kreamer M, Wheeler CE, Grencewicz DJ, Choueiry F, Chan CHF, Zakharia Y, Ma Q, Dodd RD, Ulrich CM, Hardikar S, Churchman ML, Tarhini AA, Robinson LA, Singer EA, Ikeguchi AP, McCarter MD, Tinoco G, Husain M, Jin N, Tan AC, Osman AEG, Eljilany I, Riedlinger G, Schneider BP, Benejova K, Kery M, Papandreou I, Zhu J, Denko N, Spakowicz D. Cancer Res Commun. 2024 Jun 21. doi: 10.1158/2767-9764.CRC-23-0367. PMID: 38904265

June 20

The association of structural versus load-dependent large artery stiffness mechanisms with cerebrovascular damage and cortical atrophy in humans. Armstrong MK, Jain S, Nuckols V, Pewowaruk R, Zhang X, DuBose L, Sodoma M, Madero B, Voss MW, Pierce GL. Geroscience. 2024 Jun 20. doi: 10.1007/s11357-024-01254-5. PMID: 38902456
Noninvasive Ventilation for Preoxygenation during Emergency Intubation. Gibbs KW, Semler MW, Driver BE, Seitz KP, Stempek SB, Taylor C, Resnick-Ault D, White HD, Gandotra S, Doerschug KC, Mohamed A, Prekker ME, Khan A, Gaillard JP, Andrea L, Aggarwal NR, Brainard JC, Barnett LH, Halliday SJ, Blinder V, Dagan A, Whitson MR, Schauer SG, Walker JE Jr, Barker AB, Palakshappa JA, Muhs A, Wozniak JM, Kramer PJ, Withers C, Ghamande SA, Russell DW, Schwartz A, Moskowitz A, Hansen SJ, Allada G, Goranson JK, Fein DG, Sottile PD, Kelly N, Alwood SM, Long MT, Malhotra R, Shapiro NI, Page DB, Long BJ, Thomas CB, Trent SA, Janz DR, Rice TW, Self WH, Bebarta VS, Lloyd BD, Rhoads J, Womack K, Imhoff B, Ginde AA, Casey JD; PREOXI Investigators and the Pragmatic Critical Care Research Group. N Engl J Med. 2024 Jun 20;390(23):2165-2177. doi: 10.1056/NEJMoa2313680. PMID: 38869091. Clinical Trial.

June 19

Family-Based Motivational Interviewing and Resource Mobilization to Prevent Obesity: Living Well Together Trial. Laroche HH, Andino J, O'Shea AMJ, Engebretsen B, Rice S, DeJear M Jr, Nicholson C, Yeh HW, Snetselaar L. J Nutr Educ Behav. 2024 Jun 19:S1499-4046(24)00327-0. doi: 10.1016/j.jneb.2024.05.227. PMID: 38904597
A light-responsive neural circuit suppresses feeding. Liu H, Qu N, Gonzalez NV, Palma MA, Chen H, Xiong J, Choubey A, Li Y, Li X, Yu M, Liu H, Tu L, Zhang N, Yin N, Conde KM, Wang M, Bean JC, Han J, Scarcelli NA, Yang Y, Saito K, Cui H, Tong Q, Sun Z, Wang C, Cai X, Lu L, He Y, Xu Y. J Neurosci. 2024 Jun 19:e2192232024. doi: 10.1523/JNEUROSCI.2192-23.2024. PMID: 38897723
The role of GPD1L, a sodium channel interacting gene, in the pathogenesis of Brugada Syndrome. Greiner AM, Mehdi H, Cevan C, Gutmann R, London B. Front Med (Lausanne). 2024 Jun 19;10:1159586. doi: 10.3389/fmed.2023.1159586. PMID: 38962240

June 18

Epithelial responses to CFTR modulators are improved by inflammatory cytokines and impaired by anti-inflammatory drugs. Rehman T, Pezzulo AA, Thurman AL, Zemans RL, Welsh MJ. JCI Insight. 2024 Jun 18:e181836. doi: 10.1172/jci.insight.181836. PMID: 38888974
Mutations in nonstructural proteins essential for pathogenicity in SARS-CoV-2-infected mice. Pan R, Li P, Meyerholz DK, Perlman S. J Virol. 2024 Jun 18:e0058424. doi: 10.1128/jvi.00584-24. PMID: 38888344

June 13

Noninvasive Ventilation for Preoxygenation during Emergency Intubation. Gibbs KW, Semler MW, Driver BE, Seitz KP, Stempek SB, Taylor C, Resnick-Ault D, White HD, Gandotra S, Doerschug KC, Mohamed A, Prekker ME, Khan A, Gaillard JP, Andrea L, Aggarwal NR, Brainard JC, Barnett LH, Halliday SJ, Blinder V, Dagan A, Whitson MR, Schauer SG, Walker JE Jr, Barker AB, Palakshappa JA, Muhs A, Wozniak JM, Kramer PJ, Withers C, Ghamande SA, Russell DW, Schwartz A, Moskowitz A, Hansen SJ, Allada G, Goranson JK, Fein DG, Sottile PD, Kelly N, Alwood SM, Long MT, Malhotra R, Shapiro NI, Page DB, Long BJ, Thomas CB, Trent SA, Janz DR, Rice TW, Self WH, Bebarta VS, Lloyd BD, Rhoads J, Womack K, Imhoff B, Ginde AA, Casey JD; PREOXI Investigators and the Pragmatic Critical Care Research Group. N Engl J Med. 2024 Jun 13. doi: 10.1056/NEJMoa2313680. PMID: 38869091

June 11

Dynamic measurement of airway surface liquid volume with an ex vivo trachea-chip. Scott M, Lei L, Bierstedt KC, McCray PB Jr, Xie Y. Lab Chip. 2024 Jun 11;24(12):3093-3100. doi: 10.1039/d4lc00134f. PMID: 38779981

June 10

Regulator of G protein signaling 6 (RGS6) in dopamine neurons promotes EtOH seeking, behavioral reward, and susceptibility to relapse. Spicer MM, Weber MA, Luo Z, Yang J, Narayanan NS, Fisher RA. Psychopharmacology (Berl). 2024 Jun 10. doi: 10.1007/s00213-024-06631-8. PMID: 38856764

June 8

Sex differences in the association of pretransfusion haemoglobin and cognition in preterm infants. Mostek AMB, Bell EF, Feldman HA, Josephson CD, Georgieff MK, Nopoulos P, Patel RM, Stowell SR, Sola-Visner M, Conrad AL. BMJ Paediatr Open. 2024 Jun 8;8(1):e002541. doi: 10.1136/bmjpo-2024-002541. PMID: 38851221

June 6

Association of Ground Glass Opacities with Systemic Inflammation and Progression of Emphysema. Fortis S, Guo J, Nagpal P, Chaudhary MFA, Newell JD Jr, Gerard SE, Han MK, Kazerooni EA, Martinez FJ, Barjaktarevic IZ, Barr RG, Bodduluri S, Paine Iii R, Awan HA, Schroeder JD, Gravens-Mueller LD, Ortega VE, Anderson WH, Cooper CB, Couper D, Woodruff PG, Bowler RP, Bhatt SP, Hoffman EA, Reinhardt JM, Comellas AP. Am J Respir Crit Care Med. 2024 Jun 6. doi: 10.1164/rccm.202310-1825OC. PMID: 38843116

June 3

A predominately pulmonary activation of complement in a mouse model of severe COVID-19. Szachowicz PJ, Wohlford-Lenane C, Heinen CJ, Ghimire S, Xue B, Boly TJ, Verma A, MašinoviĆ L, Bermick JR, Perlman S, Meyerholz DK, Pezzulo AA, Zhang Y, Smith RJH, McCray PB Jr. bioRxiv [Preprint]. 2024 Jun 3:2024.05.31.596892. doi: 10.1101/2024.05.31.596892. PMID: 38895461
Using a Fitbit-based Walking Game to Improve Physical Activity Among U.S. Veterans. Simmering JE, Polgreen LA, Francis SL, Strom AJ, Segre AM, Polgreen PM. Mil Med. 2024 Jun 3:usae280. doi: 10.1093/milmed/usae280. PMID: 38829720

June 1

May 31

Developing and evaluating the construct validity of a dietary pattern predictive of plasma TMAO and choline. Burns KF, LaMonte MJ, Blair RH, Tabung FK, Rexrode KM, Snetselaar LG, Millen AE. Nutr Metab Cardiovasc Dis. 2024 May 31:S0939-4753(24)00206-0. doi: 10.1016/j.numecd.2024.05.022. PMID: 39003134
Polyanhydride nanovaccine against H3N2 influenza A virus generates mucosal resident and systemic immunity promoting protection. Lopez CE, Zacharias ZR, Ross KA, Narasimhan B, Waldschmidt TJ, Legge KL. NPJ Vaccines. 2024 May 31;9(1):96. doi: 10.1038/s41541-024-00883-3.
Screening for carcinoid heart disease: Trends and future Perspectives. Mouser B, Howe JR, Atari O, Dillon JS, Chandrasekharan C, Parekh KR, Bashir MA. Int J Cardiol Cardiovasc Risk Prev. 2024 May 31;22:200293. doi: 10.1016/j.ijcrp.2024.200293. PMID: 38911359

PMID: 38822003

May 28

Extracellular histones: a unifying mechanism driving platelet-dependent extracellular vesicle release and thrombus formation in COVID-19. Eustes AS, Ahmed A, Swamy J, Patil G, Jensen M, Wilson KM, Kudchadkar S, Wahab A, Perepu U, Miller FJ Jr, Lentz SR, Dayal S. J Thromb Haemost. 2024 May 28:S1538-7836(24)00305-2. doi: 10.1016/j.jtha.2024.05.019. PMID: 38815756
Matriglycan maintains t-tubule structural integrity in cardiac muscle. Hord JM, Anderson ME, Prouty SJ, Melton S, Gastel Z, Zimmerman K, Weiss RM, Campbell KP. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2402890121. doi: 10.1073/pnas.2402890121. PMID: 38771868

May 25

Low Macular Pigment Optical Density Is Associated with Manifest Primary Open-Angle Glaucoma in Older Women. Liu Y, Lawler T, Liu Z, Thuruthumaly C, Vajaranant T, Wallace R, Tinker L, Nalbandyan M, Mares J. Curr Dev Nutr. 2024 May 25;8(6):103789. doi: 10.1016/j.cdnut.2024.103789. PMID: 38974349

May 24

Novel components in the nuclear factor-kappa B (NF-κB) signaling pathways of endothelial cells under hyperglycemic-ischemic conditions. Singh MV, Wong T, Moorjani S, Mani AM, Dokun AO. Front Cardiovasc Med. 2024 May 24;11:1345421. doi: 10.3389/fcvm.2024.1345421. PMID: 38854657
Romiplostim for Treatment of Children and Young Adults With Severe Aplastic Anemia and Myelodysplastic Syndrome. Sharathkumar A, Carr J, Claassen D, Syrbu S, Bhagavathi S, Al-Huniti A, Modi A, Bates M, Mott SL. J Pediatr Hematol Oncol. 2024 May 24. doi: 10.1097/MPH.0000000000002891. PMID: 38787686

May 23

Dynamic measurement of airway surface liquid volume with an ex vivo trachea-chip. Scott M, Lei L, Bierstedt KC, McCray PB Jr, Xie Y. Lab Chip. 2024 May 23. doi: 10.1039/d4lc00134f. PMID: 38779981
Loss of a conserved C-terminal region of the Aspergillus fumigatus AtrR transcriptional regulator leads to a gene-specific defect in target gene expression. Ror S, Stamnes MA, Moye-Rowley WS. bioRxiv [Preprint]. 2024 May 23:2024.05.22.595332. doi: 10.1101/2024.05.22.595332. PMID: 38826412

May 22

Disseminated Mycobacterium chimaera infection successfully treated with a clofazimine-containing regimen and long-term follow-up after discontinuing treatment. Kobayashi T, Ford B, Diekema DJ, Sekar P. IDCases. 2024 May 22;36:e01991. doi: 10.1016/j.idcr.2024.e01991. PMID: 38846029
Pediatric Gastrointestinal Outcomes During the Post-Acute Phase of COVID-19. Zhang D, Stein R, Lu Y, Zhou T, Lei Y, Li L, Chen J, Arnold J, Becich MJ, Chrischilles EA, Chuang CH, Christakis DA, Fort D, Geary CR, Hornig M, Kaushal R, Liebovitz DM, Mosa ASM, Morizono H, Mirhaji P, Dotson JL, Pulgarin C, Sills MR, Suresh S, Williams DA, Baldassano RN, Forrest CB, Chen Y. medRxiv [Preprint]. 2024 May 22:2024.05.21.24307699. doi: 10.1101/2024.05.21.24307699. PMID: 38826331. Preprint.

May 20

Lack of evidence for GWAS signals of exfoliation glaucoma working via monogenic loss-of-function mutation in the nearest gene. Meyer KJ, Fingert JH, Anderson MG. Hum Mol Genet. 2024 May 20:ddae088. doi: 10.1093/hmg/ddae088. PMID: 38770563

May 15

May 14

Arteriovenous metabolomics in pigs reveals CFTR regulation ofmetabolism inmultiple organs. Bae H, Kim BR, Jung S, Le J, van der Heide DM, Yu W, Park SH, Hilkin BM, Gansemer ND, Powers LS, Kang T, Meyerholz DK, Schuster VL, Jang C, Welsh MJ. J Clin Invest. 2024 May 14:e174500. doi: 10.1172/JCI174500. PMID: 38743489
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. Lei R, Qing E, Odle A, Yuan M, Gunawardene CD, Tan TJC, So N, Ouyang WO, Wilson IA, Gallagher T, Perlman S, Wu NC, Wong LR. Nat Commun. 2024 May 14;15(1):4056. doi: 10.1038/s41467-024-48104-8. PMID: 38744813
The influence of sex on activity in voluntary wheel running, forced treadmill running, and open field testing. Janowski AJ, Berardi G, Hayashi K, Plumb AN, Lesnak JB, Khataei T, Martin B, Benson CJ, Sluka KA. Res Sq [Preprint]. 2024 May 14:rs.3.rs-4365992. doi: 10.21203/rs.3.rs-4365992/v1. PMID: 38798501

May 13

Adipocyte-Specific Disruption of the BBSome Causes Metabolic and Autonomic Dysfunction. Zhao Y, Guo DF, Morgan DA, Cho YE, Rahmouni K. Am J Physiol Regul Integr Comp Physiol. 2024 May 13. doi: 10.1152/ajpregu.00039.2024. PMID: 38738295
Driving Mitochondrial Fission Improves Cognitive, but not Motor Deficits in a Mouse Model of Ataxia of Charlevoix-Saguenay. Chen C, Merrill RA, Jong CJ, Strack S. Cerebellum. 2024 May 13. doi: 10.1007/s12311-024-01701-1. PMID: 38735882
Lumbar and Thoracic Vertebrae Segmentation in CT Scans Using a 3D Multi-Object Localization and Segmentation CNN. Xiong X, Graves SA, Gross BA, Buatti JM, Beichel RR. Tomography. 2024 May 13;10(5):738-760. doi: 10.3390/tomography10050057. PMID: 38787017

May 12

Association between Body Iron Status and Cognitive Task Performance in a Nationally Representative Sample of Older Adults. Peng J, Liu B, Tan W, Hu S, Li B, Zhou J, Xu G, Sun Y, Snetselaar LG, Wallace RB, Rong S, Bao W. Aging Dis. 2024 May 12. doi: 10.14336/AD.2019.0064. PMID: 38739935

May 10

Superoxide Dismutase Mimetic Avasopasem Manganese Enhances Radiation Therapy Effectiveness in Soft Tissue Sarcomas and Accelerates Wound Healing. Zaher A, Mapuskar KA, Petronek MS, Tanas MR, Isaacson AL, Dodd RD, Milhem M, Furqan M, Spitz DR, Miller BJ, Beardsley RA, Allen BG. Antioxidants (Basel). 2024 May 10;13(5):587. doi: 10.3390/antiox13050587. PMID: 38790692

May 9

Chest CT-based automated vertebral fracture assessment using artificial intelligence and morphologic features. Nadeem SA, Comellas AP, Regan EA, Hoffman EA, Saha PK. Med Phys. 2024 May 9. doi: 10.1002/mp.17072. PMID: 38721977
Effect of Glycocalyx-targeted Therapy on Vascular Function in Older Adults: A Randomized Controlled Trial. Gimblet CJ, Ernst JW, Bell B, Bos KD, Stroud AK, Wendt LH, Donato AJ, Jalal DI, Pierce GL. J Appl Physiol (1985). 2024 May 9. doi: 10.1152/japplphysiol.00150.2024. PMID: 38722754
Hybrid deep learning and optimal graph search method for optical coherence tomography layer segmentation in diseases affecting the optic nerve. Chen Z, Zhang H, Linton EF, Johnson BA, Choi YJ, Kupersmith MJ, Sonka M, Garvin MK, Kardon RH, Wang JK. Biomed Opt Express. 2024 May 9;15(6):3681-3698. doi: 10.1364/BOE.516045. PMID: 38867777

May 8

Eosinophilic granulomatosis with polyangiitis and its association with montelukast: a case-based review. Alexander G, Moore SA, Lenert PS. Clin Rheumatol. 2024 May 8. doi: 10.1007/s10067-024-07000-8. PMID: 38720163. Review.
Interaction of serotonin/GLP-1 circuitry in a dual preclinical model for psychiatric disorders and metabolic dysfunction. Kolling LJ, Khan K, Wang R, Pierson SR, Hartman BD, Balasubramanian N, Guo DF, Rahmouni K, Marcinkiewcz CA. Psychiatry Res. 2024 May 8;337:115951. doi: 10.1016/j.psychres.2024.115951. PMID: 38735240

May 7

Cardiac monoamine oxidase-A inhibition protects against catecholamine-induced ventricular arrhythmias via enhanced diastolic calcium control. Shi Q, Malik H, Crawford RM, Streeter J, Wang J, Huo R, Shih JC, Chen B, Hall D, Abel ED, Song LS, Anderson EJ. Cardiovasc Res. 2024 May 7;120(6):596-611. doi: 10.1093/cvr/cvae012. PMID: 38198753
Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and mice. Witmer NH, Linzer CR, Boudreau RL. Cell Metab. 2024 May 7;36(5):879-881. doi: 10.1016/j.cmet.2024.02.008. PMID: 38471509

May 4

Anticipating a MERS-like coronavirus as a potential pandemic threat. Zumla A, Peiris M, Memish ZA, Perlman S. Lancet. 2024 May 4;403(10438):1729-1731. doi: 10.1016/S0140-6736(24)00641-X. PMID: 38604210

May 3

Novel methodology for nonfluoroscopic wire visualization during pulsed field ablation for the treatment of atrial fibrillation. Alzahrani A, Farjo P, Powers EM, Hodgson-Zingman D, Bailin S, Dominic P. Heart Rhythm. 2024 May 3:S1547-5271(24)02527-X. doi: 10.1016/j.hrthm.2024.04.093. PMID: 38704077
Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression. Qian Q, Li M, Zhang Z, Davis SW, Rahmouni K, Norris AW, Cao H, Ding WX, Hotamisligil GS, Yang L. Cell Metab. 2024 May 3:S1550-4131(24)00134-7. doi: 10.1016/j.cmet.2024.04.014. PMID: 38718793

May 2

Gammaherpesvirus infection triggers the formation of tRNA fragments from premature tRNAs. Manning AC, Bashir MM, Jimenez AR, Upton HE, Collins K, Lowe TM, Tucker JM. bioRxiv [Preprint]. 2024 May 2:2024.05.01.592122. doi: 10.1101/2024.05.01.592122. PMID: 38746336

May 1

April 30

The Influence of a Genetic Variant in CCDC78 on LMNA-Associated Skeletal Muscle Disease. Mohar NP, Cox EM, Adelizzi E, Moore SA, Mathews KD, Darbro BW, Wallrath LL. Int J Mol Sci. 2024 Apr 30;25(9):4930. doi: 10.3390/ijms25094930. PMID: 38732148

April 29

Best practice guidelines on genetic diagnostics of facioscapulohumeral muscular dystrophy: Update of the 2012 guidelines. Giardina E, Camaño P, Burton-Jones S, Ravenscroft G, Henning F, Magdinier F, van der Stoep N, van der Vliet PJ, Bernard R, Tomaselli PJ, Davis MR, Nishino I, Oflazer P, Race V, Vishnu VY, Williams V, Sobreira CFR, van der Maarel SM, Moore SA, Voermans NC, Lemmers RJLF. Clin Genet. 2024 Apr 29. doi: 10.1111/cge.14533. PMID: 38685133. Review.
Risk of Adverse Cardiovascular Outcomes in Postmenopausal Women with Inflammatory Bowel Disease. Greywoode R, Larson J, Peraza J, Clark R, Allison MA, Chaudhry NA, Schnatz PF, Shadyab AH, Wallace RB, Wassertheil-Smoller S. Dig Dis Sci. 2024 Apr 29. doi: 10.1007/s10620-024-08348-2. PMID: 38684633

April 26

Clinical Review of Juvenile Huntington's Disease. Oosterloo M, Touze A, Byrne LM, Achenbach J, Aksoy H, Coleman A, Lammert D, Nance M, Nopoulos P, Reilmann R, Saft C, Santini H, Squitieri F, Tabrizi S, Burgunder JM, Quarrell O; Pediatric Huntington Disease Working Group of the European Huntington Disease Network. J Huntingtons Dis. 2024 Apr 26. doi: 10.3233/JHD-231523. PMID: 38669553, Review.

April 23

NR2E3 loss disrupts photoreceptor cell maturation and fate in human organoid models of retinal development. Mullin NK, Bohrer LR, Voigt AP, Lozano LP, Wright AT, Bonilha VL, Mullins RF, Stone EM, Tucker BA.J Clin Invest. 2024 Apr 23:e173892. doi: 10.1172/JCI173892. PMID: 38652563
Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism. Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Lang MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K. J Clin Invest. 2024 Apr 23:e167371. doi: 10.1172/JCI167371. PMID: 38652544

April 22

Effect of the Mitochondrial Transaminase (GOT2) on Membrane Potential Sensitive Respiration in Mitochondria of Differentiated C2C12 Muscle Cells. Som R, Fink BD, Yu L, Sivitz WI. Am J Physiol Cell Physiol. 2024 Apr 22. doi: 10.1152/ajpcell.00576.2023. PMID: 38646781
In utero and postnatal ivacaftor/lumacaftor therapy rescues multiorgan disease in CFTR-F508del ferrets. Evans IA, Sun X, Liang B, Vegter AR, Guo L, Lynch TJ, Zhang Y, Zhang Y, Yi Y, Yang Y, Feng Z, Park SY, Shonka A, McCumber H, Qi L, Wu P, Liu G, Lacina A, Wang K, Gibson-Corley KN, Meyerholz DK, Limoli DH, Rosen BH, Yan Z, Bartels DJ, Engelhardt JF. JCI Insight. 2024 Apr 22;9(8):e157229. doi: 10.1172/jci.insight.157229. PMID: 38646935
The Reducing Agent Dithiothreitol Modulates the Ventilatory Responses That Occur in Freely Moving Rats during and following a Hypoxic-Hypercapnic Challenge. Getsy PM, Coffee GA, May WJ, Baby SM, Bates JN, Lewis SJ. Antioxidants (Basel). 2024 Apr 22;13(4):498. doi: 10.3390/antiox13040498. PMID: 38671945

April 20

L-NAC and L-NAC methyl ester prevent and overcome physical dependence to fentanyl in male rats. Bates JN, Baby SM, Getsy PM, Coffee GA, Hsieh YH, Knauss ZT, Dahan A, Bubier JA, MacFarlane PM, Mueller D, Lewis SJ. Sci Rep. 2024 Apr 20;14(1):9091. doi: 10.1038/s41598-024-59551-0. PMID: 38643270

April 19

A method for analyzing AFM force mapping data obtained from soft tissue cryosections. Wong CA, Fraticelli Guzmán NS, Read AT, Hedberg-Buenz A, Anderson MG, Feola AJ, Sulchek T, Ethier CR. J Biomech. 2024 Apr 19;168:112113. doi: 10.1016/j.jbiomech.2024.112113. PMID: 38648717

April 18

Fentanyl activates opposing opioid and non-opioid receptor systems that control breathing. Baby SM, May WJ, Getsy PM, Coffee GA, Nakashe T, Bates JN, Levine A, Lewis SJ. Front Pharmacol. 2024 Apr 18;15:1381073. doi: 10.3389/fphar.2024.1381073. PMID: 38698814
Molecular determinants and signaling effects of PKA RIα phase separation. Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, Zhang J. Mol Cell. 2024 Apr 18;84(8):1570-1584.e7. doi: 10.1016/j.molcel.2024.03.002. PMID: 38537638

April 16

Biomechanical evaluation of flash-frozen and cryo-sectioned papillary muscle samples by using sinusoidal analysis: cross-bridge kinetics and the effect of partial Ca²⁺ activation. Xi J, Feng HZ, Jin JP, Yuan J, Kawai M. J Muscle Res Cell Motil. 2024 Apr 16. doi: 10.1007/s10974-024-09667-7. PMID: 38625452

April 15

Improved pulmonary function and exercise tolerance despite persistent pulmonary fibrosis over 1 year after severe COVID-19 infection. McGroder CF, Salvatore MM, D'Souza BM, Hoffman EA, Baldwin MR, Garcia CK. Thorax. 2024 Apr 15;79(5):472-475. doi: 10.1136/thorax-2023-220370. PMID: 38514184

April 13

Exploratory Study on COPD Phenotypes and their Progression: Integrating SPECT and qCT Imaging Analysis. Li F, Zhang X, Comellas AP, Hoffman EA, Graham MM, Lin CL. medRxiv. 2024 Apr 13:2024.04.10.24305577. doi: 10.1101/2024.04.10.24305577. PMID: 38645219

April 12

Expedited Exome Reanalysis Following Deep Phenotyping and Muscle Biopsy in Suspected Mitochondrial Disorder. Pickup E, Moore SA, Suwannarat P, Grant C, Ah Mew N, Gropman A, Sen K. Pediatr Neurol. 2024 Apr 12;156:178-181. doi: 10.1016/j.pediatrneurol.2024.04.007. PMID: 38788280
Monovalent SARS-CoV-2 mRNA Vaccine Does not Boost Omicron-Specific Immune Response in Diabetic and Control Pediatric Patients. Sariol A, Vickers MA, Christensen SM, Weiskopf D, Sette A, Norris AW, Tansey MJ, Pinnaro CT, Perlman S. J Infect Dis. 2024 Apr 12;229(4):1059-1067. doi: 10.1093/infdis/jiad366. PMID: 37624979

April 11

Pancreatic enzymes digest obstructive meconium from cystic fibrosis pig intestines. Gangadharan Nambiar G, Gonzalez Szachowicz S, Zirbes CF, Hill JJ, Powers LS, Meyerholz DK, Thornell IM, Stoltz DA, Fischer AJ. Front Pediatr. 2024 Apr 11;12:1387171. doi: 10.3389/fped.2024.1387171. PMID: 38665380

April 9

Chronic obstructive pulmonary disease (COPD) and COPD-like phenotypes. Fortis S, Georgopoulos D, Tzanakis N, Sciurba F, Zabner J, Comellas AP. Front Med (Lausanne). 2024 Apr 9;11:1375457. doi: 10.3389/fmed.2024.1375457. PMID: 38654838
Distribution of 2,2',5,5'-Tetrachlorobiphenyl (PCB52) Metabolites in Adolescent Rats after Acute Nose-Only Inhalation Exposure. Bullert AJ, Li X, Gautam B, Wang H, Adamcakova-Dodd A, Wang K, Thorne PS, Lehmler HJ. Environ Sci Technol. 2024 Apr 9;58(14):6105-6116. doi: 10.1021/acs.est.3c09527. PMID: 38547313
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Tan TJC, Verma AK, Odle A, Lei R, Meyerholz DK, Matreyek KA, Perlman S, Wong LR, Wu NC. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2317222121. doi: 10.1073/pnas.2317222121. PMID: 38557175

April 8

Anticipating a MERS-like coronavirus as a potential pandemic threat. Zumla A, Peiris M, Memish ZA, Perlman S. Lancet. 2024 Apr 8:S0140-6736(24)00641-X. doi: 10.1016/S0140-6736(24)00641-X. PMID: 38604210

April 6

Effects of transcutaneous electrical nerve stimulation on pain, function, and descending inhibition in people with non-specific chronic low-back pain: a study protocol for a randomized crossover trial. Liebano RE, Sluka KA, Roy J, Savinelli M, Dailey DL, Riley SP. Trials. 2024 Apr 6;25(1):242. doi: 10.1186/s13063-024-08089-7. PMID: 38582874

April 5

Editorial: Alternative and expanding views on central respiratory chemoreception in health and disease. Eugenín J, Richerson GB. Front Physiol. 2024 Apr 5;15:1403768. doi:10.3389/fphys.2024.1403768. PMID: 3864569
Lipophilic analogues of D-cysteine prevent and reverse physical dependence to fentanyl in male rats. Bates JN, Getsy PM, Coffee GA, Baby SM, MacFarlane PM, Hsieh YH, Knauss ZT, Bubier JA, Mueller D, Lewis SJ. Front Pharmacol. 2024 Apr 5;14:1336440. doi: 10.3389/fphar.2023.1336440. PMID: 38645835

April 4

Association between survival and number of shocks for pulseless ventricular arrhythmias during pediatric in-hospital cardiac arrest in a national registry. Haskell SE, Hoyme D, Bridget Zimmerman M, Reeder R, Girotra S, Raymond TT, Samson RA, Berg M, Berg RA, Nadkarni V, Atkins DL; American Heart Association's Get With The Guidelines® - Resuscitation Investigators. Resuscitation. 2024 Apr 4:110200. doi: 10.1016/j.resuscitation.2024.110200. PMID: 38582444

April 3

Air Pollution Exposure and Interstitial Lung Features in SPIROMICS Participants with COPD. Baddour NA, Paulin LM, Gassett AJ, Woo H, Hoffman EA, Newell JD Jr, Woodruff PG, Pirozzi CS, Barjaktarevic I, Barr RG, O'Neal W, Han MK, Martinez FJ, Peters SP, Hastie AT, Hansel NN, Ortega VE, Kaufman JD, Sack CS. Ann Am Thorac Soc. 2024 Apr 3. doi: 10.1513/AnnalsATS.202308-741OC. PMID: 38568439
The Associations between Intakes of One-Carbon Metabolism-Related Vitamins and Breast Density among Young Women. Han E, Van Horn L, Snetselaar L, Shepherd JA, Park YJ, Kim H, Jung S, Dorgan JF. Cancer Epidemiol Biomarkers Prev. 2024 Apr 3;33(4):567-575. doi: 10.1158/1055-9965.EPI-23-1279. PMID: 38270539
Coagulation and platelet biology at the intersection of health and disease: illustrated capsules of the 11th Symposium on Hemostasis at the University of North Carolina. Aleman M, Arepally GM, Baglin T, Buitrago L, Davizon-Castillo P, Dayal S, Flick MJ, Gerber G, Hisada Y, Kolev K, O'Loghlen A, Rezaie AR, Sparkenbaugh EM, Stavrou EX, Ünlü B, Vercellotti GM. Res Pract Thromb Haemost. 2024 Apr 3;8(3):102395. doi: 10.1016/j.rpth.2024.102395. PMID: 38699410

April 1

March 30

Posterior Ankle Impingement: It's Not Only About the Os Trigonum. Mansur NSB, Femino JE, Chinnakkannu K, Fayed A, Glass N, Phisitkul P, Amendola A. Foot Ankle Orthop. 2024 Mar 30;9(1):24730114241241326. doi: 10.1177/24730114241241326. PMID: 38559392

March 29

Renal Complications in Patients with Predominantly Antibody Deficiency in the United States Immune Deficiency Network (USIDNET). Materne E, Zhou B, DiGiacomo D, Farmer JR, Fuleihan R, Sullivan KE, Cunningham-Rundles C, Ballas ZK, Suez D; USIDNET Consortium; Barmettler S. J Allergy Clin Immunol. 2024 Mar 29:S0091-6749(24)00326-9. doi: 10.1016/j.jaci.2024.03.014. PMID: 38555979

March 28

Daily versus three times weekly dosing for treatment of iron deficiency nonanemia in NCAA Division 1 female athletes. Schulte J, Peterson K, Thomsen T, Lentz S, Hall M, Slayman T. PM R. 2024 Mar 28. doi: 10.1002/pmrj.13172. PMID: 38545733
Distribution of 2,2',5,5'-Tetrachlorobiphenyl (PCB52) Metabolites in Adolescent Rats after Acute Nose-Only Inhalation Exposure. Bullert AJ, Li X, Gautam B, Wang H, Adamcakova-Dodd A, Wang K, Thorne PS, Lehmler HJ. Environ Sci Technol. 2024 Mar 28. doi: 10.1021/acs.est.3c09527. PMID: 38547313
Durable transgene expression and efficient re-administration after rAAV2.5T-mediated fCFTRΔR gene delivery to adult ferret lungs. Tang Y, Ebadi M, Lei J, Feng Z, Fakhari S, Wu P, Smith MD, Limberis MP, Kolbeck R, Excoffon KJ, Yan Z, Engelhardt JF. Mol Ther Methods Clin Dev. 2024 Mar 28;32(2):101244. doi: 10.1016/j.omtm.2024.101244. PMID: 38638546
Eosinophil expression of Triggering receptor expressed on myeloid cells-1 (TREM-1) restricts type 2 lung inflammation. Bowen JL, Keck K, Baruah S, Nguyen KH, Thurman AL, Pezzulo AA, Klesney-Tait J. J Leukoc Biol. 2024 Mar 28:qiae061. doi: 10.1093/jleuko/qiae061. PMID: 38547428
White-opaque switching in Candida albicans: cell biology, regulation, and function. Soll DR. Microbiol Mol Biol Rev. 2024 Mar 28:e0004322. doi: 10.1128/mmbr.00043-22. PMID: 38546228. Review.

March 27

Impact of metagenomic next-generation sequencing on clinical decision-making at an academic medical center, a retrospective study, Iowa, 2020-2022. Olthoff M, Kobayashi T, Parsons MG, Ford B, Prasidthrathsint K, Non L, Salinas JL, Diekema DJ, Ince D. Antimicrob Steward Healthc Epidemiol. 2024 Mar 27;4(1):e39. doi: 10.1017/ash.2024.31. PMID: 38562514
Neural Circuits Underlying Reciprocal Cardiometabolic Crosstalk: 2023 Arthur C. Corcoran Memorial Lecture. Rahmouni K. Hypertension. 2024 Mar 27. doi: 10.1161/HYPERTENSIONAHA.124.22066. PMID: 38533662. Review.

March 26

Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance. Palma FR, Coelho DR, Pulakanti K, Sakiyama MJ, Huang Y, Ogata FT, Danes JM, Meyer A, Furdui CM, Spitz DR, Gomes AP, Gantner BN, Rao S, Backman V, Bonini MG. Cell Rep. 2024 Mar 26;43(3):113897. doi: 10.1016/j.celrep.2024.113897. PMID: 38493478
Vessel and Airway Characteristics in One-Year CT-defined Rapid Emphysema Progression: SPIROMICS. Gerard SE, Dougherty TM, Nagpal P, Jin D, Han MK, Newell JD Jr, Saha PK, Comellas AP, Cooper CB, Couper D, Fortis S, Guo J, Hansel NN, Kanner RE, Kazeroni EA, Martinez FJ, Motahari A, Paine Iii R, Rennard S, Schroeder JD, Woodruff PG, Barr RG, Smith BM, Hoffman EA. Ann Am Thorac Soc. 2024 Mar 26. doi: 10.1513/AnnalsATS.202304-383OC. PMID: 38530051

March 25

The Increase in Household Transmission of Pertussis Associated With Diagnostic Delays. Arakkal AT, Cavanaugh JE, Polgreen PM, Miller AC. Pediatr Infect Dis J. 2024 Mar 25. doi: 10.1097/INF.0000000000004302. PMID: 38534962

March 23

Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma. Patil SV, Kaipa BR, Ranshing S, Sundaresan Y, Millar JC, Nagarajan B, Kiehlbauch C, Zhang Q, Jain A, Searby CC, Scheetz TE, Clark AF, Sheffield VC, Zode GS. Sci Rep. 2024 Mar 23;14(1):6958. doi: 10.1038/s41598-024-57286-6. PMID: 38521856

March 22

Molecular determinants and signaling effects of PKA RIα phase separation. Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, Zhang J. Mol Cell. 2024 Mar 22:S1097-2765(24)00184-9. doi: 10.1016/j.molcel.2024.03.002. PMID: 38537638

March 21

Depressive symptoms and antidepressant use in relation to white blood cell count among postmenopausal women from the Women's Health Initiative. Beydoun HA, Beydoun MA, Wassertheil-Smoller S, Saquib N, Manson JE, Snetselaar L, Weiss J, Zonderman AB, Brunner R. Transl Psychiatry. 2024 Mar 21;14(1):157. doi: 10.1038/s41398-024-02872-5. PMID: 38514652
Improved pulmonary function and exercise tolerance despite persistent pulmonary fibrosis over 1 year after severe COVID-19 infection. McGroder CF, Salvatore MM, D'Souza BM, Hoffman EA, Baldwin MR, Garcia CK. Thorax. 2024 Mar 21:thorax-2023-220370. doi: 10.1136/thorax-2023-220370. PMID: 38514184

March 20

The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort. Suri R, Markovic D, Woo H, Arjomandi M, Barr RG, Bowler RP, Criner G, Curtis JL, Dransfield MT, Drummond MB, Fortis S, Han MK, Hoffman EA, Kaner RJ, Kaufman JD, Krishnan JA, Martinez FJ, Ohar J, Ortega VE, Paine Iii R, Soler X, Woodruff PG, Hansel NN, Cooper CB, Tashkin DP, Buhr RG, Barjaktarevic IZ. Am J Respir Crit Care Med. 2024 Mar 20. doi: 10.1164/rccm.202310-1965OC. PMID: 38507607

March 18

Pharmacologic Ascorbate Radiosensitizes Pancreatic Cancer but Radioprotects Normal Tissue: The Role of Oxidative Stress-Induced Lipid Peroxidation. Chen GY, O'Leary BR, Du J, Carroll RS, Steers GJ, Buettner GR, Cullen JJ. Antioxidants (Basel). 2024 Mar 18;13(3):361. doi: 10.3390/antiox13030361. PMID: 38539894

March 15

Circadian Mechanisms in Cardiovascular and Cerebrovascular Disease. Lo EH, Faraci FM. Circ Res. 2024 Mar 15;134(6):615-617. doi: 10.1161/CIRCRESAHA.124.324462. PMID: 38484030. Review.
Comparing multiple infection control measures in a nursing home setting: a simulation study. Li H, Sewell DK, Herman T, Pemmeraju SV, Segre AM, Miller AC, Polgreen PM; CDC MInD-Healthcare Group. Infect Control Hosp Epidemiol. 2024 Mar 15:1-8. doi: 10.1017/ice.2024.43. PMID: 38487822
Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance. Palma FR, Coelho DR, Pulakanti K, Sakiyama MJ, Huang Y, Ogata FT, Danes JM, Meyer A, Furdui CM, Spitz DR, Gomes AP, Gantner BN, Rao S, Backman V, Bonini MG. Cell Rep. 2024 Mar 15;43(3):113897. doi: 10.1016/j.celrep.2024.113897. PMID: 38493478
Hypertension: Causes and Consequences of Circadian Rhythms in Blood Pressure. Faraci FM, Scheer FAJL. Circ Res. 2024 Mar 15;134(6):810-832. doi: 10.1161/CIRCRESAHA.124.323515. PMID: 38484034. Review.
TRAF3 regulation of proximal TLR signaling in B cells. Ybarra TK, Bishop GA. J Leukoc Biol. 2024 Mar 15:qiae038. doi: 10.1093/jleuko/qiae038. PMID: 38489541
Transcatheter mitral valve-in-valve explant: Lessons learned. Bashir MA, Horwitz PA, Singhal A, Panos AL, Nasr A. JTCVS Tech. 2024 Mar 15;25:63-66. doi: 10.1016/j.xjtc.2024.03.007. PMID: 38899097

March 14

Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination. Fumagalli V, Ravà M, Marotta D, Di Lucia P, Bono EB, Giustini L, De Leo F, Casalgrandi M, Monteleone E, Mouro V, Malpighi C, Perucchini C, Grillo M, De Palma S, Donnici L, Marchese S, Conti M, Muramatsu H, Perlman S, Pardi N, Kuka M, De Francesco R, Bianchi ME, Guidotti LG, Iannacone M. Nat Immunol. 2024 Mar 14. doi: 10.1038/s41590-024-01787-z. PMID: 38486021

March 13

Protein Kinase A in neurological disorders. Glebov-McCloud AGP, Saide WS, Gaine ME, Strack S. J Neurodev Disord. 2024 Mar 13;16(1):9. doi: 10.1186/s11689-024-09525-0. PMID: 38481146. Review.

March 11

MINIMAL CLINICALLY IMPORTANT CHANGE OF MOVEMENT PAIN IN MUSCULOSKELETAL PAIN CONDITIONS. Fleagle TR, Post AA, Dailey DL, Vance CGT, Zimmerman MB, Bayman EO, Crofford LJ, Sluka KA, Chimenti RL. J Pain. 2024 Mar 11:S1526-5900(24)00424-3. doi: 10.1016/j.jpain.2024.03.003. PMID: 38479557
The accuracy of detailed analysis of optical coherence tomography in detection of plaque lipid content: dual-imaging study with optical coherence tomography and near-infrared spectroscopy. Kopriva K, Chen Z, Mates M, Holy F, Stekla B, Vesela M, Pudil J, Chval M, Wahle A, Sonka M, Kovarnik T. Acta Cardiol. 2024 Mar 11:1-9. doi: 10.1080/00015385.2024.2324214. PMID: 38465606

March 8

Guiding principles on the education and practice of theranostics. Pascual TNB, Paez D, Iagaru A, Gnanasegaran G, Lee ST, Sathekge M, Buatti JM, Giammarile F, Al-Ibraheem A, Pardo MA, Baum RP, De Bari B, Ben-Haim S, Blay JY, Brink A, Estrada-Lobato E, Fanti S, Golubic AT, Hatazawa J, Israel O, Kiess A, Knoll P, Louw L, Mariani G, Mirzaei S, Orellana P, Prior JO, Urbain JL, Vichare S, Vinjamuri S, Virgolini I, Scott AM. Eur J Nucl Med Mol Imaging. 2024 Mar 8. doi: 10.1007/s00259-024-06657-2. PMID: 38453729
A T cell-based SARS-CoV-2 spike protein vaccine provides protection without antibodies. Shi J, Zheng J, Zhang X, Tai W, Compas R, Deno J, Jachym N, Verma AK, Wang G, Guan X, Odle AE, Wan Y, Li F, Perlman S, Qiao L, Du L. JCI Insight. 2024 Mar 8;9(5):e155789. doi: 10.1172/jci.insight.155789. PMID: 38456504

March 7

Candida auris screening practices at healthcare facilities in the United States: An Emerging Infections Network survey. Hennessee IP, Forsberg K, Beekmann SE, Polgreen PM, Gold JAW, Lyman M. Infect Control Hosp Epidemiol. 2024 Mar 7:1-4. doi: 10.1017/ice.2024.5. PMID: 38449379

March 6

Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and mice. Witmer NH, Linzer CR, Boudreau RL. Cell Metab. 2024 Mar 6:S1550-4131(24)00054-8. doi: 10.1016/j.cmet.2024.02.008. PMID: 38471509

March 5

Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage. Jain A, Kim BR, Yu W, Moninger TO, Karp PH, Wagner BA, Welsh MJ. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2318771121. doi: 10.1073/pnas.2318771121. PMID: 38416686

March 4

Infectious Diseases Physician Management of Cryptococcal Meningitis in North America-Is Single High-Dose Liposomal Amphotericin B Being Used? Bahr NC, Beekmann SE, Polgreen PM, Walker JB, Spec A, Boulware DR, Baddley JW. Open Forum Infect Dis. 2024 Mar 4;11(6):ofae120. doi: 10.1093/ofid/ofae120. PMID: 38887490

March 1

February 29

Airway tree caliber heterogeneity and airflow obstruction among older adults. Vameghestahbanati M, Kingdom L, Hoffman EA, Kirby M, Allen NB, Angelini E, Bertoni A, Hamid Q, Hogg JC, Jacobs DR Jr, Laine A, Maltais F, Michos ED, Sack C, Sin D, Watson KE, Wysoczanksi A, Couper D, Cooper C, Han M, Woodruff P, Tan WC, Bourbeau J, Barr RG, Smith BM. J Appl Physiol (1985). 2024 Feb 29. doi: 10.1152/japplphysiol.00694.2022. PMID: 38420676

February 28

ATF4-dependent increase in mitochondrial-endoplasmic reticulum tethering following OPA1 deletion in skeletal muscle. Hinton A Jr, Katti P, Mungai M, Hall DD, Koval O, Shao J, Vue Z, Lopez EG, Rostami R, Neikirk K, Ponce J, Streeter J, Schickling B, Bacevac S, Grueter C, Marshall A, Beasley HK, Do Koo Y, Bodine SC, Nava NGR, Quintana AM, Song LS, Grumbach IM, Pereira RO, Glancy B, Abel ED. J Cell Physiol. 2024 Feb 28. doi: 10.1002/jcp.31204. PMID: 38419397
Biomarker-assessed total energy intake and its cohort study association with all-cause mortality in postmenopausal females. Prentice RL, Aragaki AK, Zheng C, Manson JE, Tinker LF, Ravelli MN, Mossavar-Rahmani Y, Wallace RB, Tooze JA, Johnson KC, Lampe JW, Neuhouser ML, Schoeller DA. Am J Clin Nutr. 2024 Feb 28:S0002-9165(24)00166-7. doi: 10.1016/j.ajcnut.2024.02.020. PMID: 38428741

February 27

A model for stimulation of enzyme activity by a competitive inhibitor based on the interaction of terazosin and phosphoglycerate kinase 1. Riley MJ, Mitchell CC, Ernst SE, Taylor EB, Welsh MJ. Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2318956121. doi: 10.1073/pnas.2318956121. PMID: 38377207

February 23

Prevalence of frequent premature ventricular contractions and nonsustained ventricular tachycardia in older women screened for atrial fibrillation in the Women's Health Initiative. Gomez SE, Larson J, Hlatky MA, Rodriguez F, Wheeler M, Greenland P, LaMonte M, Froelicher V, Stefanick ML, Wallace R, Kooperberg C, Tinker LF, Schoenberg J, Soliman EZ, Vitolins MZ, Saquib N, Nuño T, Haring B, Perez MV. Heart Rhythm. 2024 Feb 23:S1547-5271(24)00212-1. doi: 10.1016/j.hrthm.2024.02.040. PMID: 38403238

February 22

Establishment and characterization of turtle liver organoids provides a potential model to decode their unique adaptations. Zdyrski C, Gabriel V, Gessler TB, Ralston A, Sifuentes-Romero I, Kundu D, Honold S, Wickham H, Topping NE, Sahoo DK, Bista B, Tamplin J, Ospina O, Piñeyro P, Arriaga M, Galan JA, Meyerholz DK, Allenspach K, Mochel JP, Valenzuela N. Commun Biol. 2024 Feb 22;7(1):218. doi: 10.1038/s42003-024-05818-1. PMID: 38388772

February 21

Altered 5-HT2A/C receptor binding in the medulla oblongata in the sudden infant death syndrome (SIDS): Part II. Age-associated alterations in serotonin receptor binding profiles within medullary nuclei supporting cardiorespiratory homeostasis. Cummings KJ, Leiter JC, Trachtenberg FL, Okaty BW, Darnall RA, Haas EA, Harper RM, Nattie EE, Krous HF, Mena OJ, Richerson GB, Dymecki SM, Kinney HC, Haynes RL. J Neuropathol Exp Neurol. 2024 Feb 21;83(3):144-160. doi: 10.1093/jnen/nlae004. PMID: 38323418
Calpain inhibition protects against atrial fibrillation by mitigating diabetes-associated atrial fibrosis and calcium handling dysfunction in type 2 diabetes mice. Wang Q, Yuan J, Shen H, Zhu Q, Chen B, Wang J, Zhu W, Yorek MA, Hall DD, Wang Z, Song LS. Heart Rhythm. 2024 Feb 21:S1547-5271(24)00208-X. doi: 10.1016/j.hrthm.2024.02.036. PMID: 38395244
Dietary intervention favorably influences physical functioning: the Women's Health Initiative randomized Dietary Modification trial. Chlebowski RT, Aragaki AK, Pan K, Nelson RA, Barac A, Manson JE, Stefanick ML, Ikramuddin FS, Johnson KC, Krok-Schoen JL, Laddu D, Pichardo MS, Snetselaar LG, LeBoff MS, Michael Y. J Acad Nutr Diet. 2024 Feb 21:S2212-2672(24)00091-1. doi: 10.1016/j.jand.2024.02.012. PMID: 38395355

February 20

Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins. Sylvers-Davie KL, Bierstedt KC, Schnieders MJ, Davies BSJ. Sci Rep. 2024 Feb 20;14(1):4246. doi: 10.1038/s41598-024-54705-6. PMID: 38379026
A Phase 2 Randomized Clinical Trial Evaluating 4DCT Ventilation-based Functional Lung Avoidance Radiotherapy for Non-Small Cell Lung Cancer. Baschnagel AM, Flakus MJ, Wallat EM, Wuschner AE, Chappell RJ, Bayliss RA, Kimple RJ, Christensen GE, Reinhardt JM, Bassetti MF, Bayouth JE. Int J Radiat Oncol Biol Phys. 2024 Feb 20:S0360-3016(24)00327-4. doi: 10.1016/j.ijrobp.2024.02.019. PMID: 38387810
Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism. De Solis AJ, Del Río-Martín A, Radermacher J, Chen W, Steuernagel L, Bauder CA, Eggersmann FR, Morgan DA, Cremer AL, Sué M, Germer M, Kukat C, Vollmar S, Backes H, Rahmouni K, Kloppenburg P, Brüning JC. Nat Metab. 2024 Feb 20. doi: 10.1038/s42255-024-00987-z. PMID: 38378998

February 18

Quantitative MRI Evaluation of Ferritin Overexpression in Non-Small-Cell Lung Cancer. Singhania M, Zaher A, Pulliam CF, Bayanbold K, Searby CC, Schoenfeld JD, Mapuskar KA, Fath MA, Allen BG, Spitz DR, Petronek MS.Int J Mol Sci. 2024 Feb 18;25(4):2398. doi: 10.3390/ijms25042398. PMID: 38397073

February 17

Asymptomatic Testing of Hospital Admissions for SARS-CoV-2: Is it OK to Stop? Brust KB, Kobayashi T, Diekema DJ. Clin Infect Dis. 2024 Feb 17;78(2):356-360. doi: 10.1093/cid/ciad423. PMID: 37463415
Gammaherpesvirus infection alters transfer RNA splicing and triggers tRNA cleavage. Manning AC, Bashir MM, Jimenez AR, Upton HE, Collins K, Lowe TM, Tucker JM. bioRxiv [Preprint]. 2024 Feb 17:2024.02.16.580780. doi: 10.1101/2024.02.16.580780. PMID: 38405876

February 15

Defining Parameters That Modulate Susceptibility and Protection to Respiratory Murine Coronavirus MHV1 Infection. Silva EE, Moioffer SJ, Hassert M, Berton RR, Smith MG, van de Wall S, Meyerholz DK, Griffith TS, Harty JT, Badovinac VP. J Immunol. 2024 Feb 15;212(4):563-575. doi: 10.4049/jimmunol.2300434. PMID: 38149923

February 14

Exploratory Analysis of Image-Guided Ionizing Radiation Delivery to Induce Long-Term Iron Accumulation and Ferritin Expression in a Lung Injury Model: Preliminary Results. Zaher A, Duchman B, Ivanovic M, Spitz DR, Furqan M, Allen BG, Petronek MS. Bioengineering (Basel). 2024 Feb 14;11(2):182. doi: 10.3390/bioengineering11020182. PMID: 38391668
Implementation of contact precautions for multidrug-resistant organisms in the post-COVID-19 pandemic era: An updated national Emerging Infections Network (EIN) survey. Howard-Anderson JR, Gottlieb LB, Beekmann SE, Polgreen PM, Jacob JT, Uslan DZ. Infect Control Hosp Epidemiol. 2024 Feb 14:1-6. doi: 10.1017/ice.2024.11. PMID: 38351872
Potent 3CLpro inhibitors effective against SARS-CoV-2 and MERS-CoV in animal models by therapeutic treatment. Li P, Kim Y, Dampalla CS, Nhat Nguyen H, Meyerholz DK, Johnson DK, Lovell S, Groutas WC, Perlman S, Chang K-O. mBio. 2024 Feb 14;15(2):e0287823. doi: 10.1128/mbio.02878-23. PMID: 38126789

February 12

Structure, Function, and Regulation of the Junctophilin Family. Hall DD, Takeshima H, Song LS. Annu Rev Physiol. 2024 Feb 12;86:123-147. doi: 10.1146/annurev-physiol-042022-014926. PMID: 37931168. Review.

February 9

Peripheral Blood Mononuclear Cell Gene Expression Associated with Pulmonary Microvascular Perfusion: The Multi-Ethnic Study of Atherosclerosis Chronic Obstructive Pulmonary Disease Study. Buschur KL, Pottinger TD, Vogel-Claussen J, Powell CA, Aguet F, Allen NB, Ardlie K, Bluemke DA, Durda P, Hermann EA, Hoffman EA, Lima JAC, Liu Y, Malinsky D, Manichaikul A, Motahari A, Post WS, Prince MR, Rich SS, Rotter JI, Smith BM, Tracy RP, Watson K, Winther HB, Lappalainen T, Barr RG. Ann Am Thorac Soc. 2024 Feb 9. doi: 10.1513/AnnalsATS.202305-417OC. PMID: 38335160
Radiation effects on retinal layers revealed by OCT, OCT-A, and perimetry as a function of dose and time from treatment. Tamplin MR, Wang JK, Binkley EM, Garvin MK, Hyer DE, Buatti JM, Boldt HC, Grumbach IM, Kardon RH. Sci Rep. 2024 Feb 9;14(1):3380. doi: 10.1038/s41598-024-53830-6. PMID: 38336828
A splice acceptor variant in RGS6 associated with intellectual disability, microcephaly, and cataracts disproportionately promotes expression of a subset of RGS6 isoforms. Ahlers-Dannen KE, Yang J, Spicer MM, Fu D, DeVore A, Fisher RA. J Hum Genet. 2024 Feb 9. doi: 10.1038/s10038-024-01220-1. PMID: 38332109

February 8

Investigating distributions of inhaled aerosols in the lungs of post-COVID-19 clusters through a unified imaging and modeling approach. Zhang X, Li F, Rajaraman PK, Comellas AP, Hoffman EA, Lin CL. Eur J Pharm Sci. 2024 Feb 8;195:106724. doi: 10.1016/j.ejps.2024.106724. PMID: 38340875
Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma. Huang BK, Elicker BM, Henry TS, Kallianos KG, Hahn LD, Tang M, Heng F, McCulloch CE, Bhakta NR, Majumdar S, Choi J, Denlinger LC, Fain SB, Hastie AT, Hoffman EA, Israel E, Jarjour NN, Levy BD, Mauger DT, Sumino K, Wenzel SE, Castro M, Woodruff PG, Fahy JV, Sarp FTNSARP. JCI Insight. 2024 Feb 8;9(3):e174124. doi: 10.1172/jci.insight.174124. PMID: 38127464

February 7

Altered 5-HT2A/C receptor binding in the medulla oblongata in the sudden infant death syndrome (SIDS): Part II. Age-associated alterations in serotonin receptor binding profiles within medullary nuclei supporting cardiorespiratory homeostasis. Cummings KJ, Leiter JC, Trachtenberg FL, Okaty BW, Darnall RA, Haas EA, Harper RM, Nattie EE, Krous HF, Mena OJ, Richerson GB, Dymecki SM, Kinney HC, Haynes RL. J Neuropathol Exp Neurol. 2024 Feb 7:nlae004. doi: 10.1093/jnen/nlae004. PMID: 38323418
A Comparative Study of Machine Learning and Algorithmic Approaches to Automatically Identify the Yield Point in Normal and Aneurysmal Human Aortic Tissues. Chung T, Kim J, Gueldner P, Vorp DA, Raghavan ML. J Biomech Eng. 2024 Feb 7:1-27. doi: 10.1115/1.4064365. PMID: 38323620
The effect of dietary interventions on inflammatory biomarkers among people with multiple sclerosis: A protocol for systematic review and meta-analysis of randomized controlled trials. Shemirani F, Pingel WR, Titcomb TJ, Salari-Moghaddam A, Arsalandeh F, Saxby SM, Snetselaar LG, Wahls TL. PLoS One. 2024 Feb 7;19(2):e0297510. doi: 10.1371/journal.pone.0297510. PMID: 38324543
Long-term cancer and overall mortality associated with drinking water nitrate in the United States. Mendy A, Thorne PS. Public Health. 2024 Feb 7;228:82-84. doi: 10.1016/j.puhe.2024.01.001. PMID: 38330736

February 6

Interleukin 17A Contributes to Blood-Brain Barrier Disruption of Hypothalamic Paraventricular Nucleus in Rats With Myocardial Infarction. Yu Y, Weiss RM, Wei SG. J Am Heart Assoc. 2024 Feb 6;13(3):e032533. doi: 10.1161/JAHA.123.032533. PMID: 38240234
Survival and neurological outcomes following management of intramedullary spinal metastasis patients: a case series with comprehensive review of the literature. Kritikos M, Vivanco-Suarez J, Teferi N, Lee S, Kato K, Eschbacher KL, Bathla G, Buatti JM, Hitchon PW. Neurosurg Rev. 2024 Feb 6;47(1):75. doi: 10.1007/s10143-024-02308-0. PMID: 38319484. Review.

February 5

A Bioinformatics Tool for Identifying Intratumoral Microbes from the ORIEN Dataset. Wang C, Ma A, Li Y, McNutt ME, Zhang S, Zhu J, Hoyd R, Wheeler CE, Robinson LA, Chan CHF, Zakharia Y, Dodd RD, Ulrich CM, Hardikar S, Churchman ML, Tarhini AA, Singer EA, Ikeguchi AP, McCarter MD, Denko N, Tinoco G, Husain M, Jin N, Osman AEG, Eljilany I, Tan AC, Coleman SS, Denko L, Riedlinger G, Schneider BP, Spakowicz D, Ma Q; exORIEN Consortium. Cancer Res Commun. 2024 Feb 5;4(2):293-302. doi: 10.1158/2767-9764.CRC-23-0213. PMID: 38259095

February 2

Traditional Mexican dietary pattern and cancer risk among women of Mexican descent. Loroña NC, Santiago-Torres M, Lopez-Pentecost M, Garcia L, Shadyab AH, Sun Y, Kroenke CH, Snetselaar LG, Stefanick ML, Neuhouser ML. Cancer Causes Control. 2024 Feb 2. doi: 10.1007/s10552-024-01849-5. PMID: 38305935

February 1

January 31

Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder. Mirza S, Lima CNC, Del Favero-Campbell A, Rubinstein A, Topolski N, Cabrera-Mendoza B, Kovács EHC, Blumberg HP, Richards JG, Williams AJ, Wemmie JA, Magnotta VA, Fiedorowicz JG, Gaine ME, Walss-Bass C, Quevedo J, Soares JC, Fries GR. Transl Psychiatry. 2024 Jan 31;14(1):70. doi: 10.1038/s41398-024-02760-y. PMID: 38296944

January 29

Iron-based biomarkers for personalizing pharmacological ascorbate therapy in glioblastoma: insights from a phase 2 clinical trial. Petronek MS, Bodeker KL, Lee CY, Teferi N, Eschbacher KL, Jones KA, Loeffler BT, Smith BJ, Buatti JM, Magnotta VA, Allen BG. J Neurooncol. 2024 Jan 29. doi: 10.1007/s11060-024-04571-z. PMID: 38285244

January 25

The associations between intakes of one-carbon metabolism-related vitamins and breast density among young women. Han E, Van Horn L, Snetselaar L, Shepherd JA, Park YJ, Kim H, Jung S, Dorgan JF. Cancer Epidemiol Biomarkers Prev. 2024 Jan 25. doi: 10.1158/1055-9965.EPI-23-1279. PMID: 38270539
Characterizing Foxp3⁺ and Foxp3^- T cells in the homeostatic state and after allo-activation: resting CD4⁺Foxp3⁺ Tregs have molecular characteristics of activated T cells. Liu Z, Baines KJ, Niessen NM, Heer MK, Clark D, Bishop GA, Trevillian PR. Front Immunol. 2024 Jan 25;15:1292158. doi: 10.3389/fimmu.2024.1292158. PMID: 38333213
Injectable long-acting ivacaftor-loaded poly (lactide-co-glycolide) microparticle formulations for the treatment of cystic fibrosis: In vitro characterization and in vivo pharmacokinetics in mice. Nakhla DS, Mekkawy AI, Naguib YW, Silva AD, Gao D, Ah Kim J, Alhaj-Suliman SO, Acri TM, Kumar Patel K, Ernst S, Stoltz DA, Welsh MJ, Salem AK. Int J Pharm. 2024 Jan 25;650:123693. doi: 10.1016/j.ijpharm.2023.123693. PMID: 38081555

January 24

Impact of Chronic Obstructive Pulmonary Disease in Patients with Atrial Fibrillation. An Analysis from the GLORIA-AF Registry. Romiti GF, Corica B, Mei DA, Frost F, Bisson A, Boriani G, Bucci T, Olshansky B, Chao TF, Huisman MV, Proietti M, Lip GYH; GLORIA-AF Investigators. Europace. 2024 Jan 24:euae021. doi: 10.1093/europace/euae021. PMID: 38266129

January 23

Adaptation of SARS-CoV-2 to ACE2_H353K mice reveals new spike residues that drive mouse infection. Li K, Verma A, Li P, Ortiz ME, Hawkins GM, Schnicker NJ, Szachowicz PJ, Pezzulo AA, Wohlford-Lenane CL, Kicmal T, Meyerholz DK, Gallagher T, Perlman S, McCray PB Jr. J Virol. 2024 Jan 23;98(1):e0151023. doi: 10.1128/jvi.01510-23. PMID: 38168680
A bioinformatics tool for identifying intratumoral microbes from the ORIEN dataset. Wang C, Ma A, Li Y, McNutt ME, Zhang S, Zhu J, Hoyd R, Wheeler CE, Robinson LA, Chan CHF, Zakharia Y, Dodd RD, Ulrich CM, Hardikar S, Churchman ML, Tarhini AA, Singer EA, Ikeguchi AP, McCarter MD, Denko N, Tinoco G, Husain M, Jin N, Osman AEG, Eljilany I, Tan AC, Coleman SS, Denko L, Riedlinger G, Schneider BP, Spakowicz D, Ma Q. Cancer Res Commun. 2024 Jan 23. doi: 10.1158/2767-9764.CRC-23-0213. PMID: 38259095
High ionic strength vector formulations enhance gene transfer to airway epithelia. Cooney AL, Loza LM, Najdawi K, Brommel CM, McCray PB Jr, Sinn PL. bioRxiv. 2024 Jan 23:2024.01.22.576687. doi: 10.1101/2024.01.22.576687. PMID: 38328187
Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in COPD. Opron K, Begley LA, Erb-Downward JR, Li G, Alexis NE, Barjaktarevic I, Barr RG, Bleecker ER, Boucher R, Bowler RP, Christenson SA, Comellas AP, Criner G, Cooper CB, Couper D, Galban CJ, Han MK, Hastie A, Hatt C, Hoffman EA, Kaner RJ, Kesimer M, Krishnan JA, LaFon DC, Martinez FJ, Ortega VE, Peters SP, Paine Iii R, Putcha N, Woodruff PG, Huffnagle GB, Kozik AJ, Curtis JL, Huang YJ; SPIROMICS Investigators. Am J Respir Crit Care Med. 2024 Jan 23. doi: 10.1164/rccm.202303-0489OC. PMID: 38261629

January 20

Making progress against rare cancers: A case study on neuroendocrine tumors. O'Rorke M, Chrischilles E; NET-PRO Study Investigators. Cancer. 2024 Jan 20. doi: 10.1002/cncr.35184. PMID: 38244195

January 19

Interleukin 17A Contributes to Blood-Brain Barrier Disruption of Hypothalamic Paraventricular Nucleus in Rats With Myocardial Infarction. Yu Y, Weiss RM, Wei SG. J Am Heart Assoc. 2024 Jan 19:e032533. doi: 10.1161/JAHA.123.032533. PMID: 38240234

January 18

ATF4 expression in thermogenic adipocytes is required for cold-induced thermogenesis in mice via FGF21-independent mechanisms. Bjorkman SH, Marti A, Jena J, García-Peña LM, Weatherford ET, Kato K, Koneru J, Chen J, Sood A, Potthoff MJ, Adams CM, Abel ED, Pereira RO. Sci Rep. 2024 Jan 18;14(1):1563. doi: 10.1038/s41598-024-52004-8. PMID: 38238383

January 17

Cystic Fibrosis Carrier States Are Associated With More Severe Cases of Bronchiectasis. Miller AC, Harris LM, Winthrop KL, Cavanaugh JE, Abou Alaiwa MH, Hornick DB, Stoltz DA, Polgreen PM. Open Forum Infect Dis. 2024 Jan 17;11(2):ofae024. doi: 10.1093/ofid/ofae024. PMID: 38390464
Magnetic Resonance Imaging of Iron Metabolism with T2* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM. Petronek MS, Monga V, Bodeker KL, Kwofie M, Lee CY, Mapuskar KA, Stolwijk JM, Zaher A, Wagner BA, Smith MC, Vollstedt S, Brown H, Chandler ML, Lorack AC, Wulfekuhle JS, Sarkaria JN, Flynn RT, Greenlee JDW, Howard MA, Smith BJ, Jones KA, Buettner GR, Cullen JJ, St-Aubin J, Buatti JM, Magnotta VA, Spitz DR, Allen BG. Clin Cancer Res. 2024 Jan 17;30(2):283-293. doi: 10.1158/1078-0432.CCR-22-3952. PMID: 37773633

January 16

Airway Tree Caliber and Susceptibility to Pollution-associated Emphysema: MESA Air and Lung Studies. Sack C, Wang M, Knutson V, Gassett A, Hoffman EA, Sheppard L, Barr RG, Kaufman JD, Smith B. Am J Respir Crit Care Med. 2024 Jan 16. doi: 10.1164/rccm.202307-1248OC. PMID: 38226871
Childhood Non-HDL Cholesterol and LDL Cholesterol and Adult Atherosclerotic Cardiovascular Events. Wu F, Juonala M, Jacobs DR Jr, Daniels SR, Kähönen M, Woo JG, Sinaiko AR, Viikari JSA, Bazzano LA, Burns TL, Steinberger J, Urbina EM, Venn AJ, Raitakari OT, Dwyer T, Magnussen CG. Circulation. 2024 Jan 16;149(3):217-226. doi: 10.1161/CIRCULATIONAHA.123.064296. PMID: 38014550
Vaccine Effectiveness Against Long COVID in Children. Razzaghi H, Forrest CB, Hirabayashi K, Wu Q, Allen A, Rao S, Chen Y, Bunnell HT, Chrischilles EA, Cowell LG, Cummins MR, Hanauer DA, Higginbotham M, Horne BD, Horowitz CR, Jhaveri R, Kim S, Mishkin A, Muszynski JA, Naggie S, Pajor NM, Paranjape A, Schwenk HT, Sills MR, Tedla YG, Williams DA, Bailey C. Pediatrics. 2024 Jan 16. doi: 10.1542/peds.2023-064446. PMID: 38225804

January 13

L-cysteine ethylester reverses the adverse effects of morphine on breathing and arterial blood-gas chemistry while minimally affecting antinociception in unanesthetized rats. Baby SM, May WJ, Young AP, Wilson CG, Getsy PM, Coffee GA, Lewis THJ, Hsieh YH, Bates JN, Lewis SJ. Biomed Pharmacother. 2024 Jan 13;171:116081. doi: 10.1016/j.biopha.2023.116081. PMID: 38219385
Moral Distress, Conscientious Practice, and the Endurance of Ethics in Health Care through Times of Crisis and Calm. Kaldjian LC. J Med Philos. 2024 Jan 13;49(1):11-27. doi: 10.1093/jmp/jhad041. PMID: 37769334

January 12

Immunogenicity and safety of varying dosages of a fifth-wave influenza A/H7N9 inactivated vaccine given with and without AS03 adjuvant in healthy adults. Jackson LA, Stapleton JT, Walter EB, Chen WH, Rouphael NG, Anderson EJ, Neuzil KM, Winokur PL, Smith MJ, Schmader KE, Swamy GK, Thompson AB, Mulligan MJ, Rostad CA, Cross K, Tsong R, Wegel A, Roberts PC. Vaccine. 2024 Jan 12;42(2):295-309. doi: 10.1016/j.vaccine.2023.12.001. PMID: 38105137. Clinical Trial.
Ptpn23 Controls Cardiac T-Tubule Patterning by Promoting the Assembly of Dystrophin-Glycoprotein Complex. Xu C, Zhang G, Wang X, Huang X, Zhang J, Han S, Wang J, Hall DD, Xu R, He F, Chang X, Wang F, Xie W, Wu Z, Song LS, Han P. Circulation. 2024 Jan 12. doi: 10.1161/CIRCULATIONAHA.123.065767. PMID: 38214189
A role for adverse childhood experiences and depression in preeclampsia. Myers M, Gumusoglu S, Brandt D, Stroud A, Hunter SK, Vignato J, Nuckols V, Pierce GL, Santillan MK, Santillan DA. J Clin Transl Sci. 2024 Jan 12;8(1):e25. doi: 10.1017/cts.2023.704. PMID: 38384900

January 11

Control of NAD⁺ homeostasis by autophagic flux modulates mitochondrial and cardiac function. Zhang Q, Li Z, Li Q, Trammell SA, Schmidt MS, Pires KM, Cai J, Zhang Y, Kenny H, Boudina S, Brenner C, Abel ED. EMBO J. 2024 Jan 11. doi: 10.1038/s44318-023-00009-w. PMID: 38212381
Diagnostic stewardship to improve patient outcomes and healthcare-associated infection (HAI) metrics. Singh HK, Claeys KC, Advani SD, Ballam YJ, Penney J, Schutte KM, Baliga C, Milstone AM, Hayden MK, Morgan DJ, Diekema DJ. Infect Control Hosp Epidemiol. 2024 Jan 11:1-7. doi: 10.1017/ice.2023.284. PMID: 38204365
Longitudinal Effects of Glucose-Lowering Medications on β-Cell Responses and Insulin Sensitivity in Type 2 Diabetes: The GRADE Randomized Clinical Trial. Rasouli N, Younes N, Ghosh A, Albu J, Cohen RM, DeFronzo RA, Diaz E, Sayyed Kassem L, Luchsinger JA, McGill JB, Sivitz WI, Tamborlane WV, Utzschneider KM, Kahn SE; GRADE Research Group. Diabetes Care. 2024 Jan 11:dc231070. doi: 10.2337/dc23-1070. PMID: 38211595

January 10

Cardiac MAO-A inhibition protects against catecholamine-induced ventricular arrhythmias via enhanced diastolic calcium control. Shi Q, Malik H, Crawford RM, Streeter J, Wang J, Huo R, Shih JC, Chen B, Hall D, Abel ED, Song LS, Anderson EJ. Cardiovasc Res. 2024 Jan 10:cvae012. doi: 10.1093/cvr/cvae012. PMID: 38198753
Swine models in translational research and medicine. Meyerholz DK, Burrough ER, Kirchhof N, Anderson DJ, Helke KL. Vet Pathol. 2024 Jan 10:3009858231222235. doi: 10.1177/03009858231222235. PMID: 38197394. Review.

January 9

Effects of a Remote Multimodal Intervention Involving Diet, Walking Program, and Breathing Exercise on Quality of Life Among Newly Diagnosed People with Multiple Sclerosis: A Quasi-Experimental Non-Inferiority Pilot Study. Saxby SM, Shemirani F, Crippes LJ, Ehlinger MA, Brooks L, Bisht B, Titcomb TJ, Rubenstein LM, Eyck PT, Hoth KF, Gill C, Kamholz J, Snetselaar LG, Wahls TL. Degener Neurol Neuromuscul Dis. 2024 Jan 9;14:1-14. doi: 10.2147/DNND.S441738. PMID: 38222092. Clinical Trial.

January 8

Impact of Insulin Sensitivity and β-Cell Function Over Time on Glycemic Outcomes in GRADE (Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study): Differential Treatment Effects of Dual Therapy. Utzschneider KM, Younes N, Butera NM, Balasubramanyam A, Bergenstal RM, Barzilay J, DeSouza C, DeFronzo RA, Elasy T, Krakoff J, Kahn SE, Rasouli N, Valencia WM, Sivitz WI; GRADE Research Group. Diabetes Care. 2024 Jan 8:dc231059. doi: 10.2337/dc23-1059. PMID: 38190619

January 5

Treg cell dysfunction and cutaneous exposure to S. aureus underlie eczema in DOCK8 deficiency. Wilkie H, Das M, Pelovitz T, Bainter W, Woods B, Alasharee M, Sobh A, Baris S, Eltan SB, Al-Herz W, Barbouche MR, Ben-Mustapha I, Ben-Ali M, Sallam MTH, Awad A, Lotfy S, El Marsafy A, Ezzelarab M, Farrar M, Schmidt BAR, NandyMazumdar M, Guttman-Yassky E, Sheets A, Vidic KM, Murphy G, Schlievert PM, Chou J, Leyva-Castillo JM, Janssen E, Timilshina M, Geha RS. J Allergy Clin Immunol. 2024 Jan 5:S0091-6749(24)00005-8. doi: 10.1016/j.jaci.2023.12.020. PMID: 38185418

January 4

Structural Predictors of Lung Function Decline in Young Smokers with Normal Spirometry. Ritchie AI, Donaldson GC, Hoffman EA, Allinson JP, Bloom CI, Bolton CE, Choudhury G, Gerard SE, Guo J, Alves-Moreira L, McGarvey L, Sapey E, Stockley RA, Yip KP, Singh D, Wilkinson T, Fageras M, Ostridge K, Jöns O, Bucchioni E, Compton CH, Jones P, Mezzi K, Vestbo J, Calverley PMA, Wedzicha JA. Am J Respir Crit Care Med. 2024 Jan 4. doi: 10.1164/rccm.202307-1203OC. PMID: 38175920

January 3

Adaptation of SARS-CoV-2 to ACE2_H353K mice reveals new spike residues that drive mouse infection. Li K, Verma A, Li P, Ortiz ME, Hawkins GM, Schnicker NJ, Szachowicz PJ, Pezullo A, Wohlford-Lenane CL, Kicmal T, Meyerholz DK, Gallagher T, Perlman S, McCray PB Jr. J Virol. 2024 Jan 3:e0151023. doi: 10.1128/jvi.01510-23. PMID: 38168680

January 2

B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Wu CG, Balakrishnan VK, Merrill RA, Parihar PS, Konovolov K, Chen YC, Xu Z, Wei H, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Chung WK, Honkanen RE, Suzuki A, Huang X, Strack S, Xing Y. Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e2310727120. doi: 10.1073/pnas.2310727120. PMID: 38150499
The Cerebellar Cognitive Affective/Schmahmann Syndrome Scale in Spinocerebellar Ataxias. Selvadurai LP, Perlman SL, Ashizawa T, Wilmot GR, Onyike CU, Rosenthal LS, Shakkottai VG, Paulson HL, Subramony SH, Bushara KO, Kuo SH, Dietiker C, Geschwind MD, Nelson AB, Gomez CM, Opal P, Zesiewicz TA, Hawkins T, Yacoubian TA, Nopoulos PC, Sha SJ, Morrison PE, Figueroa KP, Pulst SM, Schmahmann JD. Cerebellum. 2024 Jan 2. doi: 10.1007/s12311-023-01651-0. PMID: 38165578
Knockdown of the Non-canonical Wnt Gene Prickle2 Leads to Cerebellar Purkinje Cell Abnormalities While Cerebellar-Mediated Behaviors Remain Intact. Abbott PW, Hardie JB, Walsh KP, Nessler AJ, Farley SJ, Freeman JH, Wemmie JA, Wendt L, Kim YC, Sowers LP, Parker KL. Cerebellum. 2024 Jan 2. doi: 10.1007/s12311-023-01648-9. PMID: 38165577
Visualization of Optic Nerve Structural Patterns in Papilledema Using Deep Learning Variational Autoencoders. Wang JR, Linton EF, Johnson BA, Kupersmith MJ, Garvin MK, Kardon RH. Transl Vis Sci Technol. 2024 Jan 2;13(1):13. doi: 10.1167/tvst.13.1.13. PMID: 38231498

January 1

François M. Abboud Cardiovascular Research Center

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